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    Article

    Zebrafish diras1 Promoted Neurite Outgrowth in Neuro-2a Cells and Maintained Trigeminal Ganglion Neurons In Vivo via Rac1-Dependent Pathway

    The small GTPase Ras superfamily regulates several neuronal functions including neurite outgrowth and neuron proliferation. In this study, zebrafish diras1a and diras1b were identified and were found to be mainly...

    Chi-Wei Yeh, Li-Sung Hsu in Molecular Neurobiology (2016)

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    Article

    Decreased Kruppel-like factor 4 (KLF4) expression may correlate with poor survival in gastric adenocarcinoma

    Kruppel-like factors (KLFs) play either anti- or pro-proliferation roles in different human cancers. Here, we investigated the expression of KLF4 in gastric cancers and its correlation with clinicopathological...

    Li-Sung Hsu, Chien-Pin Chan, Chih-Jung Chen, Shu-Hui Lin in Medical Oncology (2013)

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    Zebrafish rgs4 is essential for motility and axonogenesis mediated by Akt signaling

    The schizophrenia susceptibility gene, Rgs4, is one of the most intensively studied regulators of G-protein signaling members, well known to be fundamental in regulating neurotransmission. However, little is know...

    Yi-Chuan Cheng, Paul J. Scotting, Li-Sung Hsu in Cellular and Molecular Life Sciences (2013)

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    Expression of Krűppel-like factor 5 in gastric cancer and its clinical correlation in Taiwan

    Krűppel-like factors (KLFs), highly conserved zinc-finger proteins, play either anti- or pro-proliferation roles in different human cancers through regulating a wide range of genes’ expression. Here, we invest...

    Maw-Soan Soon, Li-Sung Hsu, Chih-Jung Chen, Pei-Yi Chu, Jia-Hung Liou in Virchows Archiv (2011)

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    Article

    Mutation ofgyrA andparC in clinical isolates ofAcinetobacter baumannii and its relationship with antimicrobial drugs resistance in Taiwan

    Acinetobacter baumannii is a species of non fermentative Gram-negative bacteria commonly found in water and soil. This organism was susceptible to most antibiotics in the 1970s. It has now become...

    Shang-Tao Chien, Chun-Hsiu Lin, Jui-Chen Hsueh, Pei-Ling Li in Annals of Microbiology (2009)

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    Article

    Cloning, expression and chromosomal localization of human Ca2+/calmodulin-dependent protein kinase kinase

    A human cDNA clone encoding the calcium/calmodulin-dependent protein kinase kinase (CaMKK) was isolated by RT-PCR amplification of the fragment corresponding to the conserved kinase catalytic domain followed b...

    Li-Sung Hsu, Ann-** Tsou, Chin-Wen Chi, Chen-Hsen Lee in Journal of Biomedical Science (1998)