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  1. No Access

    Article

    Integration of Transformative Platforms for the Discovery of Causative Genes in Cardiovascular Diseases

    Cardiovascular diseases are the leading cause of morbidity and mortality worldwide. Genome-wide association studies (GWAS) are powerful epidemiological tools to find genes and variants associated with cardiova...

    Haocheng Lu, Jifeng Zhang, Y. Eugene Chen… in Cardiovascular Drugs and Therapy (2021)

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    Article

    Suppression of Vascular Macrophage Activation by Nitro-Oleic Acid and its Implication for Abdominal Aortic Aneurysm Therapy

    Abdominal aortic aneurysm (AAA) is one of the leading causes of death in the developed world and is currently undertreated due to the complicated nature of the disease. Herein, we aimed to address the therapeu...

    Yang Zhao, Ziyi Chang, Guizhen Zhao, Haocheng Lu… in Cardiovascular Drugs and Therapy (2021)

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    Article

    Novel Drug Targets for Atrial Fibrillation Identified Through Mendelian Randomization Analysis of the Blood Proteome

    Novel, effective, and safe preventive therapy targets for AF are still needed. Circulating proteins with causal genetic evidence are promising candidates. We aimed to systematically screen circulating proteins...

    Zuodong Ning, Yunying Huang, Haocheng Lu, Yong Zhou… in Cardiovascular Drugs and Therapy (2023)