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  1. Article

    Open Access

    γ-2 and GSG1L bind with comparable affinities to the tetrameric GluA1 core

    The AMPA-type ionotropic glutamate receptor mediates fast excitatory neurotransmission in the brain. A variety of auxiliary subunits regulate its gating properties, assembly, and trafficking, but it is unknown...

    Chenlu Yu, Hendrik F. P. Runge, Antara Mukhopadhyay… in Cellular & Molecular Biology Letters (2023)

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  2. Article

    Open Access

    AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability

    AMPA-type glutamate receptors (AMPARs), key elements in excitatory neurotransmission in the brain, are macromolecular complexes whose properties and cellular functions are determined by the co-assembled consti...

    Aline Brechet, Rebecca Buchert, Jochen Schwenk, Sami Boudkkazi… in Nature Communications (2017)

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    Article

    Native GABAB receptors are heteromultimers with a family of auxiliary subunits

    A proteomics study of GABAB receptors, the receptors for γ-aminobutyric acid, the main inhibitory neurotransmitter in the brain, throws new light on the origin of their functional diversity. Rather than being het...

    Jochen Schwenk, Michaela Metz, Gerd Zolles, Rostislav Turecek, Thorsten Fritzius… in Nature (2010)

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    Article

    Neuronal nicotinic acetylcholine receptors and autosomal dominant nocturnal frontal lobe epilepsy: a critical review

    Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) is a distinct human epileptic syndrome. In some families, it is associated with mutations of the α4 or the β2 subunit of the neuronal nicotinic acet...

    Bernd Sutor, Gerd Zolles in Pflügers Archiv (2001)