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28 EFFECTS OF PHENOBARBITAL ON CEREBRAL HEMODYNAMICS IN PRETERM NEONATES
We evaluated the effect of phenobarbital (pb) versus placebo (saline) on cerebral hemodynamics in eleven, clinically stable preterm neonates. The mean (+SD) post natal age at study entry was 12 (3) hours. The ...
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Article
EFFECT OF HYPOXIC-ISCHEMIC (H-I) BRAIN DAMAGE ON GLUTAMATE RELEASE AND Dl MARKERS IN THE NEWBORN PIGLET
Glutamate is an important: excitatory aminoacid neurotransmitter that mediates neuronal death. Dopamine has also ben implicated, an endugenous substance in the pathogenesis of H-I brain damage. We studied the ...
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Article
Radioiodinated tracers for the evaluation of dopamine receptors in the neonatal rat brain after hypoxic-ischemic injury
In order to evaluate in vivo single-photon emission tomography (SPET) method of assessing cerebral function after hypoxic-ischemic injury in human neonates, we studied D1 and D2 dopamine receptors in a rat model....
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A PHASE 1 STUDY OF INTRAVENTRICULAR RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR FOR THE TREATMENT OF POSTHEMORRHAGIC HYDROCEPHALUS. • 2278
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EFFECTS OF APNEA AND BRADYCARDIA ON CEREBRAL HAEMODYNAMICS AND ELECTRO-ENCEPHALOGRAM (EEG) in preterm infants. • 1438
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QUANTITATIVE T2 MRI STUDY OF BRAIN INJURIES IN PRETERM INFANTS: CORRELATION WITH NEURODEVELOPMENTAL OUTCOME. † 1030
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EFFECTS OF HYPOXIC-ISCHEMIC (HI) BRAIN INJURY ON DOPAMINE D2 RECEPTORS IN TERM NEWBORNS:A SPECT STUDY. † 1759
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EFFECT OF CEREBRAL HYPOXIA-ISCHEMIA (HI) ON CEREBRAL OXYGEN CONSUMPTION(CMO2) IN NEWBORN PIGLETS DURING THE FIRST TWO DAYS OF CEREBRAL REPERFUSION.† 853
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Quantitative assessment of metabolic changes during brain development with 1H Magnetic Resonance Spectroscopy (MRS) in vivo in two animal models † 957
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Cognitive disturbances in 5 year old premature children : an Event- Related Potential study (ERP) 1335
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Maternal Exposure to LPS Induces Hypomyelination in the Internal Capsule and Programmed Cell Death in the Deep Gray Matter in Newborn Rats
Epidemiologic and experimental findings implicate maternal infection in the etiology of injury to brain white matter, which may lead to cerebral palsy in preterm newborns. In the present study, inflammation an...
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Article
Lamotrigine Is Neuroprotective in the Energy Deficiency Model of MPTP Intoxicated Mice
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) inhibits the mitochondrial complex I of the respiratory chain. This results in ATP and ion homeostasis disturbances, which lead to selective death of the...
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Article
Opening wedge osteotomy of the first cuneiform for the treatment of hallux valgus
We performed an opening wedge osteotomy of the first cuneiform for the correction of all degrees of hallux valgus deformities. A wedge-shaped graft maintained the open wedge osteotomy and decreased the metatar...
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Open AccessNational study on the adequacy of antidotes stocking in Lebanese hospitals providing emergency care
Antidotes stocking is a critical component of hospital care for poisoned patients in emergency. Antidote stocking represents a major health challenge worldwide and in Lebanon. Systematic data monitoring of ant...
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Article
Systematic ultrasound examinations in neonates admitted to NICU: evolution of portal vein thrombosis
The aim of the study was to better describe incidence, risk factors, and the natural evolution of neonatal portal vein thrombosis (PVT).
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Article
Incomplete Gestation has an Impact on Cognitive Abilities in Autism Spectrum Disorder
Extreme prematurity is known as a risk factor for autism spectrum disorder (ASD). However, the association between prematurity and ASD, for children born moderately and late preterm (MLPT) and those born early...
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Article
Are single-donor red blood cell transfusions still relevant for preterm infants?
To explore the worth of a single-donor program for preterm infants through the recipient profile and the impact on donor exposure, red blood cell (RBC) pack waste, storage duration, and transfusion performance.
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Article
Open AccessA plant plasma-membrane H+-ATPase promotes yeast TORC1 activation via its carboxy-terminal tail
The Target of Rapamycin Complex 1 (TORC1) involved in coordination of cell growth and metabolism is highly conserved among eukaryotes. Yet the signals and mechanisms controlling its activity differ among taxa,...
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Duration of mechanical ventilation is more critical for brain growth than postnatal hydrocortisone in extremely preterm infants
Hydrocortisone is used in preterm infants. However, early disruption of growth velocities was observed in infants exposed to hydrocortisone. This retrospective study aimed to explore the postnatal brain growth...
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Open AccessPartial protective effects of melatonin on develo** brain in a rat model of chorioamnionitis
Melatonin has shown promising neuroprotective effects due to its anti-oxidant, anti-inflammatory and anti-apoptotic properties, making it a candidate drug for translation to humans in conditions that compromis...