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Article
Open AccessPartial protective effects of melatonin on develo** brain in a rat model of chorioamnionitis
Melatonin has shown promising neuroprotective effects due to its anti-oxidant, anti-inflammatory and anti-apoptotic properties, making it a candidate drug for translation to humans in conditions that compromis...
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Article
Open AccessA plant plasma-membrane H+-ATPase promotes yeast TORC1 activation via its carboxy-terminal tail
The Target of Rapamycin Complex 1 (TORC1) involved in coordination of cell growth and metabolism is highly conserved among eukaryotes. Yet the signals and mechanisms controlling its activity differ among taxa,...
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Article
Open AccessNational study on the adequacy of antidotes stocking in Lebanese hospitals providing emergency care
Antidotes stocking is a critical component of hospital care for poisoned patients in emergency. Antidote stocking represents a major health challenge worldwide and in Lebanon. Systematic data monitoring of ant...
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Article
Lamotrigine Is Neuroprotective in the Energy Deficiency Model of MPTP Intoxicated Mice
The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) inhibits the mitochondrial complex I of the respiratory chain. This results in ATP and ion homeostasis disturbances, which lead to selective death of the...
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Article
Maternal Exposure to LPS Induces Hypomyelination in the Internal Capsule and Programmed Cell Death in the Deep Gray Matter in Newborn Rats
Epidemiologic and experimental findings implicate maternal infection in the etiology of injury to brain white matter, which may lead to cerebral palsy in preterm newborns. In the present study, inflammation an...
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Quantitative assessment of metabolic changes during brain development with 1H Magnetic Resonance Spectroscopy (MRS) in vivo in two animal models † 957
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Cognitive disturbances in 5 year old premature children : an Event- Related Potential study (ERP) 1335
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QUANTITATIVE T2 MRI STUDY OF BRAIN INJURIES IN PRETERM INFANTS: CORRELATION WITH NEURODEVELOPMENTAL OUTCOME. † 1030
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EFFECTS OF HYPOXIC-ISCHEMIC (HI) BRAIN INJURY ON DOPAMINE D2 RECEPTORS IN TERM NEWBORNS:A SPECT STUDY. † 1759
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EFFECT OF CEREBRAL HYPOXIA-ISCHEMIA (HI) ON CEREBRAL OXYGEN CONSUMPTION(CMO2) IN NEWBORN PIGLETS DURING THE FIRST TWO DAYS OF CEREBRAL REPERFUSION.† 853
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A PHASE 1 STUDY OF INTRAVENTRICULAR RECOMBINANT TISSUE PLASMINOGEN ACTIVATOR FOR THE TREATMENT OF POSTHEMORRHAGIC HYDROCEPHALUS. • 2278
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EFFECTS OF APNEA AND BRADYCARDIA ON CEREBRAL HAEMODYNAMICS AND ELECTRO-ENCEPHALOGRAM (EEG) in preterm infants. • 1438
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EFFECT OF HYPOXIC-ISCHEMIC (H-I) BRAIN DAMAGE ON GLUTAMATE RELEASE AND Dl MARKERS IN THE NEWBORN PIGLET
Glutamate is an important: excitatory aminoacid neurotransmitter that mediates neuronal death. Dopamine has also ben implicated, an endugenous substance in the pathogenesis of H-I brain damage. We studied the ...
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Article
28 EFFECTS OF PHENOBARBITAL ON CEREBRAL HEMODYNAMICS IN PRETERM NEONATES
We evaluated the effect of phenobarbital (pb) versus placebo (saline) on cerebral hemodynamics in eleven, clinically stable preterm neonates. The mean (+SD) post natal age at study entry was 12 (3) hours. The ...