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Article
Accelerated Gradient-Free Optimization Methods with a Non-Euclidean Proximal Operator
We propose an accelerated gradient-free method with a non-Euclidean proximal operator associated with the p-norm (1 ⩽ p ⩽ 2). We obtain estimates for the rate of convergence of the method under low noise arising ...
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Article
On the Upper Bound for the Expectation of the Norm of a Vector Uniformly Distributed on the Sphere and the Phenomenon of Concentration of Uniform Measure on the Sphere
We consider the problem of constructing upper bounds for the expectation of the norm of a vector uniformly distributed on the Euclidean unit sphere.
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Article
Ergoferon Increases IL-2 Production by Activated Lymphocytes
We studied the effects of Ergoferon on the production of antiviral cytokine IL-2 by type 1 CD4+T cells. Preincubation of Jurkat cells with Ergoferon increased IL-2 secretion by these cells after stimulation with ...
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Article
Accelerated Directional Search with Non-Euclidean Prox-Structure
We consider smooth convex optimization problems whose full gradient is not available for their numerical solution. In 2011, Yu.E. Nesterov proposed accelerated gradient-free methods for solving such problems. ...
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Article
Reachability of Optimal Convergence Rate Estimates for High-Order Numerical Convex Optimization Methods
The Monteiro–Svaiter accelerated hybrid proximal extragradient method (2013) with one step of Newton’s method used at every iteration for the approximate solution of an auxiliary problem is considered. The Mon...
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Article
Effects of Release-Active Antibodies to CD4 Receptor on the Level of lck-Kinase in Cultured Mononuclear Cells from Human Peripheral Blood
For evaluation of effects of release-active antibodies to CD4 on cultured lymphocytes from human peripheral blood, we measured intracellular content of lck-kinase cell-based ELISA. In cells treated with releas...
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Article
Subetta Enhances Sensitivity of Human Muscle Cells to Insulin
Addition of Subetta to insulin (10 nM) increased insulin-stimulated glucose uptake 43% (p<0.001). Moreover, glucose uptake stimulated by insulin (10 nM) in the presence of Subetta was similar to that stimulated b...
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Article
Open AccessSubetta increases phosphorylation of insulin receptor β-subunit alone and in the presence of insulin
It has been previously shown that Subetta (a drug containing released-active forms of antibodies to the insulin receptor β-subunit and antibodies to endothelial nitric oxide synthase) stimulated insulin-induce...
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Article
Device for measuring the energy density of laser radiation with the aid of a ferromagnetic element