33 Result(s)

Article

New advances of NG2-expressing cell subset in marrow mesenchymal stem cells as novel therapeutic tools for liver fibrosis/cirrhosis

Bone marrow-derived mesenchymal stem cell (_BMMSC)-based therapy has become a major focus for treating liver fibrosis/cirrhosis. However, although these cell therapies promote the treatment of this disease, the he...

Deyu Hu, Jiejuan Lai, Quanyu Chen, Lianhua Bai in Stem Cell Research & Therapy (2024)

Article

Genome assembly of M. spongiola and comparative genomics of the genus Morchella provide initial insights into taxonomy and adaptive evolution

Morchella spongiola is a highly prized mushroom for its delicious flavor and medical value and is one of the most flourishing, representative, and dominant macrofungi in the Qilian Mountains of the Qinghai-Tibet ...

Qing Meng, Zhanling **e, Hongyan Xu, **g Guo, Qingqing Peng, Yanyan Li… in BMC Genomics (2024)

Article

De novo and somatic structural variant discovery with SVision-pro

Long-read-based de novo and somatic structural variant (SV) discovery remains challenging, necessitating genomic comparison between samples. We developed SVision-pro, a neural-network-based instance segmentati...

Songbo Wang, Jiadong Lin, Peng Jia, Tun Xu, **ujuan Li… in Nature Biotechnology (2024)

Article

Dietary inflammation index is associated with dyslipidemia: evidence from national health and nutrition examination survey, 1999–2019

This study aimed to investigate the association between the Dietary Inflammatory Index (DII) and dyslipidemia, as well as to evaluate the mortality risk associated with DII in participants with dyslipidemia.

**aozhe Chen, Chunlei Hou, Lei Yao, Jianhua Li, Mingtai Gui… in Lipids in Health and Disease (2023)

Article

Integrated analysis of the ubiquitination mechanism reveals the specific signatures of tissue and cancer

Ubiquitination controls almost all cellular processes. The dysregulation of ubiquitination signals is closely associated with the initiation and progression of multiple diseases. However, there is little compr...

Deyu Long, Ruiqi Zhang, Changjian Du, Jiapei Tong, Yu Ni, Yaqi Zhou… in BMC Genomics (2023)

Article

Correction to: Develo** a salinity tolerance indicator for tree varieties at challenging sites and urban forests based on inferences of physiological responses: an example of Ulmus pumila

Deyu Mu, Chen Ding in Trees (2023)

Article

CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity

cGAS/DncV-like nucleotidyltransferase (CD-NTase) family members are immune sensors that synthesize diverse nucleotide signals to initiate antiviral response in bacteria and animals. As a founding member of CD-...

Hansen Liu, Zhenzhen Yan, Deyu Zhu, Haiyan Xu, Feng Liu… in Cell Death & Differentiation (2023)

Article

NtMYB12 requires for competition between flavonol and (pro)anthocyanin biosynthesis in Narcissus tazetta tepals

The color of flowers is one of the main characteristics adopted for plants to attract pollinators to ensure the reproductive success of the plant, they are also important in their ornamental appeal in Narcissus p...

**gwen Yang, ** Wu, Cristina belen Aucapiña, Deyu Zhang… in Molecular Horticulture (2023)

Article

SSELM-neg: spherical search-based extreme learning machine for drug–target interaction prediction

The experimental verification of a drug discovery process is expensive and time-consuming. Therefore, efficiently and effectively identifying drug–target interactions (DTIs) has been the focus of research. At ...

Lingzhi Hu, Chengzhou Fu, Zhonglu Ren, Yongming Cai, ** Yang… in BMC Bioinformatics (2023)

Article

Hepatocyte growth factor-mediated apoptosis mechanisms of cytotoxic CD8⁺ T cells in normal and cirrhotic livers

Intrahepatic stem/progenitor cells and cytotoxic CD8⁺ T cells (CD8⁺ T cells) in the cirrhotic liver undergo apoptosis, which potentially facilitates progression to cancer. Here, we report that hepatocyte growth f...

Quanyu Chen, Min Yan, Heng Lin, Jiejuan Lai, Zhiqing Yang, Deyu Hu… in Cell Death Discovery (2023)

Article

Correction to: DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis

A Correction to this paper has been published: https://doi.org/10.1038/s41418-021-00736-9

Menglang Yuan, **nsheng Zhang, **gbo Zhang, Keyong Wang… in Cell Death & Differentiation (2022)

Article

A glucose-like metabolite deficient in diabetes inhibits cellular entry of SARS-CoV-2

The severity and mortality of COVID-19 are associated with pre-existing medical comorbidities such as diabetes mellitus. However, the underlying causes for increased susceptibility to viral infection in patien...

Liangqin Tong, Min Li, Shisong Fang, Enhao Ma, ** Yu… in Nature Metabolism (2022)

Article

Ferroptosis-associated DNA methylation signature predicts overall survival in patients with head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a common cancer characterized by late diagnosis and poor prognosis. The aim of this study was to identify a novel ferroptosis-related DNA methylation signature ...

Yuanyuan Xu, Min Hong, Deyu Kong, Jun Deng, Zhaoming Zhong, ** Liang in BMC Genomics (2022)

Article

Avibactam potentiated the activity of both ceftazidime and aztreonam against S. maltophilia clinical isolates in vitro

Treatment options for Stenotrophomonas maltophilia (S. maltophilia) infections were limited. We assessed the efficacy of ceftazidime (CAZ), ceftazidime-avibactam (CAZ-AVI), aztreonam (ATM), and aztreonam-avibacta...

Qiuxia Lin, Hua Zou, **an Chen, Menglu Wu, Deyu Ma, Hanbing Yu… in BMC Microbiology (2021)

Article

miR-362-5p promotes cell proliferation and cell cycle progression by targeting GAS7 in acute myeloid leukemia

Recently, miR-362-5p has attracted special interest as a novel prognostic predictor in acute myeloid leukemia (AML). However, its biological function and underlying molecular mechanism in AML remain to be furt...

Fuqun Wu, Changxin Yin, Junhua Qi, Deyu Duan, ** Jiang, Jianhua Yu… in Human Cell (2020)

Article

Comparative transcriptomics of stem bark reveals genes associated with bast fiber development in Boehmeria nivea L. gaud (ramie)

Boehmeria nivea L. Gaud (Ramie) produces one of the longest natural fibers in nature. The bark of ramie mainly comprises of the phloem tissue of stem and is the raw material for fiber. Therefore, identifying the ...

Jiyong **e, Jiaqi Li, Yucheng Jie, Deyu **e, Di Yang, Huazhong Shi… in BMC Genomics (2020)

Article

DC-SIGN–LEF1/TCF1–miR-185 feedback loop promotes colorectal cancer invasion and metastasis

DC-SIGN is previously focused on its physiologic and pathophysiologic roles in immune cells. Little is known about whether DC-SIGN is expressed in malignant epithelial cells and how DC-SIGN participates in tum...

Menglang Yuan, **nsheng Zhang, **gbo Zhang, Keyong Wang… in Cell Death & Differentiation (2020)

Article

MicroRNA-153-3p enhances cell radiosensitivity by targeting BCL2 in human glioma

Glioma is the most prevalent malignant tumor in human central nervous systems. Recently, the development of resistance to radiotherapy in glioma patients markedly vitiates the therapy outcome. MiR-153-3p has b...

Deyu Sun, Yi Mu, Haozhe Piao in Biological Research (2018)

Article

The PilZ domain of MrkH represents a novel DNA binding motif

Feng Wang, Qing He, Kaixuan Su, Fei Gao, Yan Huang, Zong Lin, Deyu Zhu… in Protein & Cell (2016)

Article

PslG, a self-produced glycosyl hydrolase, triggers biofilm disassembly by disrupting exopolysaccharide matrix

Biofilms are surface-associated communities of microorganism embedded in extracellular matrix. Exopolysaccharide is a critical component in the extracellular matrix that maintains biofilm architecture and prot...

Shan Yu, Tiantian Su, Huijun Wu, Shiheng Liu, Di Wang, Tianhu Zhao… in Cell Research (2015)