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    Modulation of anthracycline-induced cytotoxicity by targeting the prenylated proteome in myeloid leukemia cells

    Deregulation of Ras/ERK signaling in myeloid leukemias makes this pathway an interesting target for drug development. Myeloid leukemia cell lines were screened for idarubicin-induced apoptosis, cell-cycle prog...

    Michael A. Morgan, Fredrick O. Onono, H. Peter Spielmann… in Journal of Molecular Medicine (2012)