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Shikonin attenuates hyperhomocysteinemia-induced CD4+ T cell inflammatory activation and atherosclerosis in ApoE−/− mice by metabolic suppression

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  1. Article

    Omega-3 PUFA ameliorates hyperhomocysteinemia-induced hepatic steatosis in mice by inhibiting hepatic ceramide synthesis

    Hyperhomocysteinemia (HHcy) is a key risk factor in hepatic steatosis. In this study, we applied a metabolomic approach to investigate the changes in the metabolite profile due to HHcy-induced hepatic steatosi...

    Yong-qiang Dong, **ng-zhong Zhang, Lu-lu Sun, Song-yang Zhang… in Acta Pharmacologica Sinica (2017)

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  2. Article

    High glucose stimulates TNFα and MCP-1 expression in rat microglia via ROS and NF-κB pathways

    To investigate whether high glucose stimulates the expression of inflammatory cytokines and the possible mechanisms involved.

    Yi Quan, Chang-tao Jiang, Bing Xue, Shi-gong Zhu, **an Wang in Acta Pharmacologica Sinica (2011)

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