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Genome-wide association study identifies a novel locus for cannabis dependence

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  1. Article

    Open Access

    17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson’s disease are associated with LRRC37A/2 expression in astrocytes

    Parkinson’s disease (PD) is genetically associated with the H1 haplotype of the MAPT 17q.21.31 locus, although the causal gene and variants underlying this association have not been identified.

    Kathryn R. Bowles, Derian A. Pugh, Yiyuan Liu, Tulsi Patel in Molecular Neurodegeneration (2022)

  2. Article

    Open Access

    Genome-wide polygenic scores for age at onset of alcohol dependence and association with alcohol-related measures

    Age at onset of alcohol dependence (AO-AD) is a defining feature of multiple drinking typologies. AO-AD is heritable and likely shares genetic liability with other aspects of alcohol consumption. We examine wh...

    M Kapoor, Y-L Chou, H J Edenberg, T Foroud, N G Martin in Translational Psychiatry (2016)