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  1. No Access

    Article

    Cells expressing preproenkephalin mRNA in the rat pineal gland are not serotonin-producing pinealocytes: Evidence usingin Situ hybridization combined with immunocytochemistry for serotonin

    1. Preproenkephalin (PPEnk) mRNA expressing cells have been identified in rat pineal gland using radioactivein situ hybridization histochemistry.

    **-Tao Wang, George D. Pappas, Jacqueline Sagen in Cellular and Molecular Neurobiology (1996)

  2. No Access

    Article

    Multiple kinetic components of exocytosis distinguished by neurotoxin sensitivity

    The secretion of synaptic and other vesicles is a complex process involving multiple steps. Many molecular components of the secretory apparatus have been identified, but how they relate to the different stage...

    Tao Xu, Thomas Binz, Heiner Niemann, Erwin Neher in Nature Neuroscience (1998)

  3. No Access

    Article

    Glial cell responses, complement and apolipoprotein J expression following axon injury in the neonatal rat

    Immature motoneurons are highly susceptible to degeneration following axon injury. The response of perineuronal glia to axon injury may significantly influence neuronal survival and axon regeneration. We have ...

    Ran Tao, Håkan Aldskogius in Journal of Neurocytology (1999)

  4. No Access

    Article

    Visual input induces long-term potentiation of develo** retinotectal synapses

    Early visual experience is essential in the refinement of develo** neural connections. In vivo whole-cell recording from the tectum of Xenopus tadpoles showed that repetitive dimming-light stimulation applied t...

    Li I. Zhang, Hui-zhong W. Tao, Mu-ming Poo in Nature Neuroscience (2000)

  5. No Access

    Article

    Probing ion permeation and gating in a K+ channel with backbone mutations in the selectivity filter

    Potassium channels selectively conduct K+ ions across cell membranes, and use diverse mechanisms to control their gating. We studied ion permeation and gating of an inwardly rectifying K+ channel by individually ...

    Tao Lu, Alice Y. Ting, Joel Mainland, Lily Y. Jan, Peter G. Schultz in Nature Neuroscience (2001)

  6. No Access

    Article

    Role of the chemokine SDF-1 as the meningeal attractant for embryonic cerebellar neurons

    Migration of neuronal precursor cells from the external germinal layer (EGL) to the internal granular layer (IGL) is a crucial process in the development of the mammalian cerebellar cortex. These cells make up...

    Yan Zhu, Tao Yu, **ao-Chun Zhang, Takashi Nagasawa, Jane Y. Wu in Nature Neuroscience (2002)

  7. No Access

    Article

    Differential regulation of synaptic and extra-synaptic NMDA receptors

    A variety of processes limit NMDA (N-methyl-D-aspartate) receptor (NMDAR) activity in response to agonist exposure, including rundown—the decline of peak current with repeated, sustained agonist application1,2,3,

    Bo Li, Nansheng Chen, Tao Luo, Yo Otsu, Timothy H. Murphy in Nature Neuroscience (2002)

  8. Article

    Age-Related Changes in Cochlear Endolymphatic Potassium and Potential in CD-1 and CBA/CaJ Mice

    The CD-1 mouse strain is known to have early onset of hearing loss that is progressive with aging. We sought to determine whether a disturbance of K+ homeostasis and pathological changes in the cochlear lateral w...

    Tao Wu, Daniel C. Marcus in Journal of the Association for Research in Otolaryngology (2003)

  9. Article

    Localization and Functional Studies of Pendrin in the Mouse Inner Ear Provide Insight About the Etiology of Deafness in Pendred Syndrome

    Immunolocalization studies of mouse cochlea and vestibular end-organ were performed to study the expression pattern of pendrin, the protein encoded by the Pendred syndrome gene (PDS), in the inner ear. The protei...

    Ines E. Royaux, Inna A. Belyantseva, Tao Wu in Journal of the Association for Research in… (2003)

  10. No Access

    Article

    A novel model of motor learning capable of develo** an optimal movement control law online from scratch

    A computational model of a learning system (LS) is described that acquires knowledge and skill necessary for optimal control of a multisegmental limb dynamics (controlled object or CO), starting from “knowing”...

    Yury P. Shimansky, Tao Kang, Ji** He in Biological Cybernetics (2004)

  11. No Access

    Article

    Pharmacological study of the novel compound FLZ against experimental parkinson’s models and its active mechanism

    FLZ is a synthetic new derivative of squamosamide. Pharmacological study found that FLZ given orally improved the abnormal behavior caused by the functional disturbance of dopaminergic and cholinergic neurons ...

    WeiHong Feng, HuaiLing Wei, Geng Tao Liu in Molecular Neurobiology (2005)

  12. No Access

    Article

    bHLH genes and retinal cell fate specification

    The various cell types in the vertebrate retina arise from a pool of common progenitors. The way that the cell types are specified has been a long-standing issue. Decades of research have yielded a large body ...

    Run-Tao Yan, Wenxin Ma, Lina Liang, Shu-Zhen Wang in Molecular Neurobiology (2005)

  13. Article

    Open Access

    Role of spinal cord glutamate transporter during normal sensory transmission and pathological pain states

    Glutamate is a neurotransmitter critical for spinal excitatory synaptic transmission and for generation and maintenance of spinal states of pain hypersensitivity via activation of glutamate receptors. Understa...

    Yuan-**ang Tao, Jianguo Gu, Robert L Stephens Jr in Molecular Pain (2005)

  14. No Access

    Article

    Identification of Up-Regulated Genes After Complete Spinal Cord Transection in Adult Rats

    Spinal cord injury (SCI) initiates a cascade of events and these responses to injury are likely to be mediated and reflected by changes in mRNA concentrations. As a step towards understanding the complex mecha...

    Zhenlian Ma, Tao Liu, **n Li, Tao Zhou, in Cellular and Molecular Neurobiology (2006)

  15. No Access

    Article

    Molecular approaches to brain asymmetry and handedness

  16. The left and right hemispheres of the human brain have distinct functions: for example, the left is normally dominant for language and logical processing, wher...

  17. Tao Sun, Christopher A. Walsh in Nature Reviews Neuroscience (2006)

  18. No Access

    Article

    The virtue of simplicity

    Multiple local motions must be combined to determine the direction of object motion, which is harder than it seems. A new paper proposes an elegant and simple solution to this problem, eminently realizable in ...

    Tao Zhang, Kenneth H Britten in Nature Neuroscience (2006)

  19. Article

    Open Access

    Recent advances in basic neurosciences and brain disease: from synapses to behavior

    Understanding basic neuronal mechanisms hold the hope for future treatment of brain disease. The 1st international conference on synapse, memory, drug addiction and pain was held in beautiful downtown Toronto,...

    Guo-Qiang Bi, Vadim Bolshakov, Guojun Bu, Catherine M Cahill in Molecular Pain (2006)

  20. Article

    Open Access

    Inward currents induced by ischemia in rat spinal cord dorsal horn neurons

    Hypoxia and ischemia occur in the spinal cord when blood vessels of the spinal cord are compressed under pathological conditions such as spinal stenosis, tumors, and traumatic spinal injury. Here by using spin...

    Meng Chen, Yuan-**ang Tao, Jianguo G Gu in Molecular Pain (2007)

  21. Article

    Open Access

    Genetic knockout and pharmacologic inhibition of neuronal nitric oxide synthase attenuate nerve injury-induced mechanical hypersensitivity in mice

    Neuronal nitric oxide synthase (nNOS) is a key enzyme for nitric oxide production in neuronal tissues and contributes to the spinal central sensitization in inflammatory pain. However, the role of nNOS in neur...

    Yun Guan, Myron Yaster, Srinivasa N Raja, Yuan-**ang Tao in Molecular Pain (2007)

  22. No Access

    Article

    Defining cortical frequency tuning with recurrent excitatory circuitry

    Neurons in the recipient layers of sensory cortices receive excitatory input from two major sources: the feedforward thalamocortical and recurrent intracortical inputs. To address their respective functional r...

    Bao-hua Liu, Guangying K Wu, Robert Arbuckle, Huizhong W Tao in Nature Neuroscience (2007)

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