473 Result(s)

Article

Investigating distinct clinical features and constructing a nomogram model for survival probability in adults with cerebellar high-grade gliomas

The clinical features of cerebellar high-grade gliomas (cHGGs) in adults have not been thoroughly explored. This large-scale, population-based study aimed to comprehensively outline these traits and construct ...

Tao Chang, Rui Zhang, Jiahao Gan, Yuan Yang, Yanhui Liu, Yan Ju, **aodong Niu… in BMC Cancer (2024)

Article

Author Correction: LINE-1 transcription activates long-range gene expression

**ufeng Li, Luyao Bie, Yang Wang, Yaqiang Hong, Ziqiang Zhou, Yiming Fan… in Nature Genetics (2024)

Article

Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial

Recent single-arm studies involving neoadjuvant camrelizumab, a PD-1 inhibitor, plus chemotherapy for resectable locally advanced esophageal squamous cell carcinoma (LA-ESCC) have shown promising results. This...

Jianjun Qin, Liyan Xue, Anlin Hao, **aofeng Guo, Tao Jiang, Yunfeng Ni… in Nature Medicine (2024)

Article

Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validation

Wilms tumor (WT) is the most common pediatric embryonal tumor. Improving patient outcomes requires advances in understanding and targeting the multiple genes and cellular control pathways, but its pathogenesis...

Qiang Zeng, Tingting Liu, Lilu Qin, Chen Wang, Guangbei Peng, Zhong Liu… in BMC Cancer (2024)

Article

Correction to: Preclinical studies of Flonoltinib Maleate, a novel JAK2/FLT3 inhibitor, in treatment of JAK2^V617F-induced myeloproliferative neoplasms

Mengshi Hu, Tao Yang, Linyu Yang, Lu Niu, **bing Zhu, Ailin Zhao… in Blood Cancer Journal (2024)

Article

A novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension

Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...

Jia-zhou Ye, Hua-ze Lu, Can Zeng, Guo Lei, **ao-bo Wang, Jie Chen, Tao Bai… in BMC Cancer (2024)

Article

Correlation between hemoglobin and the risk of common malignant tumors: a 1999–2020 retrospective analysis and causal association analysis

The role of hemoglobin (HGB) in common malignant tumors remains unclear.

Guo-Sheng Li, Tao Huang, **g-**ao Li, Jun Liu, **ang Gao, Nuo Yang… in BMC Cancer (2024)

Article

TACE combined Lenvatinib plus Camrelizumab versus TACE alone in efficacy and safety for unresectable hepatocellular carcinoma: a propensity score-matching study

To compare the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined Lenvatinib plus Camrelizumab (TLC) in unresectable hepatocellular carcinoma (uHCC) with those of TACE alone .

Zhihong Tang, Tao Bai, Tao Wei, **aobo Wang, Jie Chen, Jiazhou Ye, Shangqi Li… in BMC Cancer (2024)

Article

Genomic analyses reveal the stepwise domestication and genetic mechanism of curd biogenesis in cauliflower

Cauliflower (Brassica oleracea L. var. botrytis) is a distinctive vegetable that supplies a nutrient-rich edible inflorescence meristem for the human diet. However, the genomic bases of its selective breeding hav...

Rui Chen, Ke Chen, **ngwei Yao, **aoli Zhang, Yingxia Yang, **ao Su… in Nature Genetics (2024)

Article

Causal relationship between lipid-lowering drugs and ovarian cancer, cervical cancer: a drug target mendelian randomization study

The causal impact of lipid-lowering drugs on ovarian cancer (OC) and cervical cancer (CC) has received considerable attention, but its causal relationship is still a subject of debate. Hence, the objective of ...

**shuai Li, Zixian Yang, Tao Wang, Mengqi Li, **angjian Wu, **aoyan Fu… in BMC Cancer (2024)

Article

Clinical application of serum tumor abnormal protein in prostate cancer patients

To explore the clinical value of tumor abnormal protein (TAP) in the diagnosis and prognosis evaluation of prostate cancer.

Liusong Fu, Chi Zhang, Zewen Wang, Wei Tao, ** Zhu, Yibin Zhou… in BMC Cancer (2024)

Article

The role of adjuvant transcatheter arterial chemoembolization following repeated curative resection/ablation for hepatocellular carcinoma with early recurrence: a propensity score matching analysis

The role of adjuvant transcatheter arterial chemoembolization (TACE) following repeated resection/ablation for recurrent hepatocellular carcinoma (HCC) remains uncertain. The aim of this study was to assess th...

Kaiquan Huang, Tao Qian, Wen Chen, Mengyi Lao, Huiliang Li, Wei-Chiao Lin… in BMC Cancer (2024)

Article

Artificial intelligence-based prognostic model accurately predicts the survival of patients with diffuse large B-cell lymphomas: analysis of a large cohort in China

Diffuse large B-cell lymphomas (DLBCLs) display high molecular heterogeneity, but the International Prognostic Index (IPI) considers only clinical indicators and has not been updated to include molecular data....

Huilin Peng, Mengmeng Su, **ang Guo, Liang Shi, Tao Lei, Haifeng Yu, Jieyu Xu… in BMC Cancer (2024)

Article

UCHL5 promotes hepatocellular carcinoma progression by promoting glycolysis through activating Wnt/β-catenin pathway

Hepatocellular carcinoma (HCC) is highly malignant with a dismal prognosis, although the available therapies are insufficient. No efficient ubiquitinase has been identified as a therapeutic target for HCC desp...

Baishun Wan, Ming Cheng, Tao He, Ling Zhang in BMC Cancer (2024)

Article

Ferroptosis is a protective factor for the prognosis of cancer patients: a systematic review and meta-analysis

Cancer is a leading global cause of death. Conventional cancer treatments like surgery, radiation, and chemotherapy have associated side effects. Ferroptosis, a nonapoptotic and iron-dependent cell death, has ...

Shen Li, Kai Tao, Hong Yun, Jiaqing Yang, Yuanling Meng, Fan Zhang, Xuelei Ma in BMC Cancer (2024)

Article

Does depressurization of the portal vein before liver transplantation affect the recurrence of HCC? A nested case-control study

Portal hypertension (PHT) has been proven to be closely related to the development of hepatocellular carcinoma (HCC). Whether PHT before liver transplantation (LT) will affect the recurrence of HCC is not clear.

Guo Wei, Yong Zhao, Shifeng Feng, **gsheng Yuan, Gang Xu, Tao Lv, Jian Yang… in BMC Cancer (2024)

Article

Downregulation of GPX8 in hepatocellular carcinoma: impact on tumor stemness and migration

GPX8, which is found in the endoplasmic reticulum lumen, is a member of the Glutathione Peroxidases (GPXs) family. Its role in hepatocellular carcinoma (HCC) is unknown.

Chen-Yang Tao, **ao-Ling Wu, Shu-Shu Song, Zheng Tang, Yu-Fu Zhou… in Cellular Oncology (2024)

Article

Targeting PCSK9 to upregulate MHC-II on the surface of tumor cells in tumor immunotherapy

Proprotein convertase subtilisin/kexin type 9 (PCSK9), the last member of the proprotein convertase family, functions as a classic regulator of low-density lipoprotein (LDL) by interacting with low-density lip...

Hanbing Wang, **n Zhang, Yipeng Zhang, Tao Shi, Yue Zhang, Xueru Song… in BMC Cancer (2024)

Article

Real-world advantage and challenge of post-autologous stem cell transplantation MRD negativity in high-risk patients with double-hit multiple myeloma

Autologous stem-cell transplantation (ASCT) remains a beneficial approach for patients with newly diagnosed multiple myeloma (NDMM) in the age of novel therapeutic agents. Nevertheless, limited real-world data...

Yi Tao, Shiwei **, Dan Yang, Mengmeng Pan, Wanyan Ouyang, Yuanfang Liu… in BMC Cancer (2024)

Article

Author Correction: Anti-GD2 CAR-NKT cells in relapsed or refractory neuroblastoma: updated phase 1 trial interim results

Andras Heczey, **n Xu, Amy N. Courtney, Gengwen Tian… in Nature Medicine (2024)