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    Article

    Evaluation of fragility fracture risk using deep learning based on ultrasound radio frequency signal

    It was essential to identify individuals at high risk of fragility fracture and prevented them due to the significant morbidity, mortality, and economic burden associated with fragility fracture. The quantitat...

    Wenqiang Luo, Jionglin Wu, Zhiwei Chen, Peidong Guo, Qi Zhang, Baiying Lei in Endocrine (2024)

  2. Article

    Open Access

    A membrane associated tandem kinase from wild emmer wheat confers broad-spectrum resistance to powdery mildew

    Crop wild relatives offer natural variations of disease resistance for crop improvement. Here, we report the isolation of broad-spectrum powdery mildew resistance gene Pm36, originated from wild emmer wheat, that...

    Miaomiao Li, Huaizhi Zhang, Huixin **ao, Keyu Zhu, Wenqi Shi in Nature Communications (2024)

  3. Article

    Open Access

    Improving enteral nutrition tolerance and protein intake maybe beneficial to intensive care unit patients

    Enteral nutrition (EN) is important for critically ill patients. This study investigated the current situation of EN treatment in SHANGHAI intensive care units (ICUs). We hypothesized that improving EN practic...

    Ming Zhong, Yuzhen Qiu, Tingting Pan, Ruilan Wang, Yuan Gao in Scientific Reports (2023)

  4. Article

    Open Access

    In-vivo programmable acoustic manipulation of genetically engineered bacteria

    Acoustic tweezers can control target movement through the momentum interaction between an acoustic wave and an object. This technology has advantages over optical tweezers for in-vivo cell manipulation due to ...

    Ye Yang, Yaozhang Yang, Dingyuan Liu, Yuanyuan Wang, Minqiao Lu in Nature Communications (2023)

  5. Article

    Open Access

    Phase-separation facilitated one-step fabrication of multiscale heterogeneous two-aqueous-phase gel

    Engineering heterogeneous hydrogels with distinct phases at various lengths, which resemble biological tissues with high complexity, remains challenging by existing fabricating techniques that require complica...

    Feipeng Chen, **ufeng Li, Yafeng Yu, Qingchuan Li, Haisong Lin in Nature Communications (2023)

  6. Article

    Accuracy of the intermittently scanned continuous glucose monitoring system in critically ill patients: a prospective, multicenter, observational study

    Continuous glucose monitoring (CGM) has the potential to improve glucose control in the intensive care unit (ICU) setting. We sought to evaluate the accuracy of the intermittently scanned CGM (isCGM) system in...

    Weifeng Huang, Siwan Li, **gyi Lu, Yun Shen, Yaxin Wang, Yufei Wang in Endocrine (2022)

  7. Article

    Open Access

    Chemical forms of cadmium in soil and its distribution in French marigold sub-cells in response to chelator GLDA

    The use of degradable chelating agents to facilitate phytoextraction is a promising low-cost method for the remediation of heavy metal-contaminated soils. However, there are few studies on how plants and soils...

    Hongchuan Li, Deming Kong, Borui Zhang, Yusef Kianpoor Kalkhajeh in Scientific Reports (2022)

  8. Article

    Open Access

    Author Correction: Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways

    Yingchuan Li, Zhen Zeng, Yongmei Cao, Yu**g Liu, Feng ** in Scientific Reports (2022)

  9. Article

    Open Access

    Author Correction: Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways

    Yingchuan Li, Zhen Zeng, Yongmei Cao, Yu**g Liu, Feng ** in Scientific Reports (2021)

  10. Article

    Open Access

    Non-associative phase separation in an evaporating droplet as a model for prebiotic compartmentalization

    The synthetic pathways of life’s building blocks are envisaged to be through a series of complex prebiotic reactions and processes. However, the strategy to compartmentalize and concentrate biopolymers under p...

    Wei Guo, Andrew B. Kinghorn, Yage Zhang, Qingchuan Li in Nature Communications (2021)

  11. Article

    Open Access

    Bi/BiOCl Nanosheets Enriched with Oxygen Vacancies to Enhance Photocatalytic CO2 Reduction

    BiOCl has been used in the photoreduction of CO2, but exhibits limited photocatalytic activity. In this study, Bi was in situ reduced and deposited on the surface of (001)-dominated BiOCl nanosheets by NaBH4 to f...

    Shuqi Wu, Junbu Wang, Qingchuan Li, Zeai Huang in Transactions of Tian** University (2021)

  12. Article

    Open Access

    Adjuvant chemotherapy after radical nephroureterectomy improves the survival outcome of high-risk upper tract urothelial carcinoma patients with cardiovascular comorbidity

    This prospective randomized comparative trial study aimed to evaluate the therapeutic outcomes of radical nephroureterectomy and adjuvant chemotherapy (ACT) used in combination in high risk upper tract urothel...

    Yong Luo, Bingfu Feng, Dechao Wei, Yili Han, Mingchuan Li in Scientific Reports (2020)

  13. Article

    Open Access

    Programmed magnetic manipulation of vesicles into spatially coded prototissue architectures arrays

    In nature, cells self-assemble into spatially coded tissular configurations to execute higher-order biological functions as a collective. This mechanism has stimulated the recent trend in synthetic biology to ...

    Qingchuan Li, Shubin Li, **angxiang Zhang, Weili Xu, **aojun Han in Nature Communications (2020)

  14. Article

    Open Access

    Flow cytometric characterisation of the complex polyploid genome of Saccharum officinarum and modern sugarcane cultivars

    Sugarcane (Saccharum spp.) is a globally important crop for sugar and bioenergy production. Its highly polyploid, complex genome has hindered progress in understanding its molecular structure. Flow cytometric sor...

    Cushla J. Metcalfe, **gchuan Li, Debora Giorgi, Jaroslav Doležel in Scientific Reports (2019)

  15. Article

    Open Access

    Genetic map** and evolutionary analysis of human-expanded cognitive networks

    Cognitive brain networks such as the default-mode network (DMN), frontoparietal network, and salience network, are key functional networks of the human brain. Here we show that the rapid evolutionary cortical ...

    Yongbin Wei, Siemon C. de Lange, Lianne H. Scholtens in Nature Communications (2019)

  16. Article

    Open Access

    Genome sequence of the progenitor of the wheat D genome Aegilops tauschii

    A combination of advanced sequencing and map** techniques is used to produce a reference genome of Aegilops tauschii, progenitor of the wheat D genome, providing a valuable resource for comparative genetic stud...

    Ming-Cheng Luo, Yong Q. Gu, Daniela Puiu, Hao Wang, Sven O. Twardziok in Nature (2017)

  17. Article

    Open Access

    Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways

    Acute respiratory distress syndrome (ARDS) caused by severe sepsis remains a major challenge in intensive care medicine. ACE2 has been shown to protect against lung injury. However, the mechanisms of its prote...

    Yingchuan Li, Zhen Zeng, Yongmei Cao, Yu**g Liu, Feng ** in Scientific Reports (2016)

  18. Article

    Open Access

    Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis prevents lipopolysaccharide–induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF–κB pathways

    ACE2 and Ang–(1–7) have important roles in preventing acute lung injury. However, it is not clear whether upregulation of the ACE2/Ang–(1–7)/Mas axis prevents LPS–induced injury in pulmonary microvascular endo...

    Yingchuan Li, Yongmei Cao, Zhen Zeng, Mengfan Liang, Ying Xue in Scientific Reports (2015)