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Conjugation of Lysozyme and Epigallocatechin Gallate for Improving Antibacterial and Antioxidant Properties
One of the main interests in the food industry is the preservation of food from spoilage by microorganisms or lipid oxidation. A novel alternative is...
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Enhancing Phosphate Uptake and Antifungal Activity in Tomato Plants via Bacillus licheniformis Mutagenesis: Evaluating Growth Parameters
The objective of the investigation was to improve phosphate solubilization in tomato plants by Bacillus licheniformis , a rhizobacterium that promotes...
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Factors influencing haulout behaviour of non-breeding weddell seals (Leptonychotes weddellii) at Cape Royds, Antarctica
The Weddell seal ( Leptonychotes weddellii ) is a fast-ice obligate species that plays an important role as both predator and prey within the...
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IL-4/IL-4R axis signaling drives resistance to immunotherapy by inducing the upregulation of Fcγ receptor IIB in M2 macrophages
In recent years, immunotherapy, particularly PD-1 antibodies, have significantly enhanced the outcome of gastric cancer patients. Despite these...
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A study on bioremoval of a neonicotinoid insecticide, imidacloprid, by a newly isolated Acremonium sclerotigenum
A neonicotinoid insecticide, imidacloprid (IMI), has been widely used by seed treatment to control the sucking and biting insects since the nineties....
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Biochemical characterisation and production kinetics of high molecular-weight (HMW) putative antibacterial proteins of insect pathogenic Brevibacillus laterosporus isolates
BackgroundBacterial genomes often encode structures similar to phage capsids (encapsulins) and phage tails which can be induced spontaneously or...
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The ubiquitin-like protein UBTD1 promotes colorectal cancer progression by stabilizing c-Myc to upregulate glycolysis
Dysfunction of the ubiquitin-proteasome system (UPS) is involved in the pathogenesis of various malignancies including colorectal cancer (CRC)....
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From yeast screening for suitability as single cell protein to fed-batch cultures
Purpose: Fed-batch cultures have rarely been used in single cell protein (SCP) research. This work evaluated multiple yeast species for suitability...
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KKL-35 inhibits growth of Staphylococcus aureus by systematically changing bacterial phenotypes
KKL-35 is a new oxadiazole compound with potent broad-spectrum antibacterial activity against a number of gram-positive and gram-negative bacteria....
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Green Extraction of Anthocyanins from Prunus domestica Using Natural Deep Eutectic Solvents: Anti-sickling Properties and Phenolic Impact Assessment
Natural Deep Eutectic Solvents (NADESs) are a form of green solvents used to extract phenolic compounds and are considered a more environmentally...
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A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage
Many CRISPR–Cas (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein) systems, which provide bacteria with...
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Nuclear alpha-synuclein accelerates cell senescence and neurodegeneration
BackgroundThe progression of Parkinson’s disease (PD) is related to ageing. The accumulation of nuclear alpha-synuclein (α-syn) may accelerate the...
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The excito-repellent activity of five essential oils extracted from local plants against dengue and malaria vectors in Burkina Faso
Using chemical insecticides remains the main way to prevent and manage dengue and malaria, two main mosquito-borne diseases. However, the vectors of...
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Orchestration of antiviral responses within the infected central nervous system
Many newly emerging and re-emerging viruses have neuroinvasive potential, underscoring viral encephalitis as a global research priority. Upon entry...
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AXDND1 is required to balance spermatogonial commitment and for sperm tail formation in mice and humans
Dynein complexes are large, multi-unit assemblies involved in many biological processes via their critical roles in protein transport and axoneme...
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An altered uterine microbiota with endometrial hyperplasia
BackgroundEndometrial hyperplasia (EH) is a precursor to endometrial cancer, and the role of the microbiome in its development is unclear.
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Comparative genomics of Vibrio toranzoniae strains
Vibrio toranzoniae is a marine bacterium belonging to the Splendidus clade that was originally isolated from healthy clams in Galicia (NW Spain). Its...
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Increased ONECUT2 induced by Helicobacter pylori promotes gastric cancer cell stemness via an AKT-related pathway
Helicobacter pylori (HP) infection initiates and promotes gastric carcinogenesis. ONECUT2 shows promise for tumor diagnosis, prognosis, and...
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Combined neurokinin-1 receptor antagonist and sorafenib is a promising approach for hepatocellular carcinoma therapy
BackgroundHCC (Hepatocellular carcinoma) is the most common primary malignant cancer in the liver. Treatment options to incurable HCC such as...