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Article
Open AccessPrenatal, perinatal and parental risk factors for autism spectrum disorder in China: a case- control study
Autism spectrum disorder (ASD) is heritable neurodevelopmental disorders (NDDs), but environmental risk factors have also been suggested to a play a role in its development. Prenatal, perinatal and parental fa...
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Article
Preparation of Porous TiO2/PVDF/CA Fibers for Photocatalytic Degradation of Dyes by Centrifugal Spinning
A facile method for the preparation of porous micro/nano fibers was demonstrated. The TiO2/PVDF/CA-composite micro/nano fibers were prepared by centrifugal spinning and then CA was removed by a selective dissolut...
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Article
The Divergence of Inequality in Healthcare Utilization Between Poor- and Rich-Medical Resource Regions: Evidence from the Middle-Aged and Older Adults in China
The healthcare utilization inequality among middle-aged and older adults has been a serious concern shared in the aging process. Successful policy implementation regarding the supply of medical resources and t...
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Article
Open AccessPhenotypic characterisation of regulatory T cells in patients with gestational diabetes mellitus
Gestational diabetes mellitus (GDM) is a common complication that occurs during pregnancy. Emerging evidence suggests that immune abnormalities play a pivotal role in the development of GDM. Specifically, regu...
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Article
Natural variation of Grain size 3 allele differentially functions in regulating grain length in xian/indica and geng/japonica rice
Grain yield in rice is largely determined by grain size. Grain Size 3 (GS3) is a major quantitative trait locus for grain size. The C–A natural variation in the second exon of GS3 was reported to play an importan...
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Article
Open AccessComprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer
As the largest transporter family impacting on tumor genesis and development, the prognostic value of solute carrier (SLC) members has not been elucidated in colorectal cancer (CRC). We aimed to identify a pro...
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Article
Open AccessTreatment for locally resectable stage IIIC1r cervical cancer: surgery or chemoradiotherapy?
The aim of this study was to compare the therapeutic value and treatment-related complications of radical hysterectomy with those of concurrent chemoradiotherapy (CCRT) for locally resectable (T1a2–T2a1) stage...
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Article
Open AccessKetogenic diet-produced β-hydroxybutyric acid accumulates brain GABA and increases GABA/glutamate ratio to inhibit epilepsy
Ketogenic diet (KD) alleviates refractory epilepsy and reduces seizures in children. However, the metabolic/cell biologic mechanisms by which the KD exerts its antiepileptic efficacy remain elusive. Herein, we...
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Article
Open AccessAssociations between cardiometabolic multimorbidity and cerebrospinal fluid biomarkers of Alzheimer’s disease pathology in cognitively intact adults: the CABLE study
Cardiometabolic multimorbidity is associated with an increased risk of dementia, but the pathogenic mechanisms linking them remain largely undefined. We aimed to assess the associations of cardiometabolic mult...
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Article
Retraction Note: Autophagy regulated by lncRNA HOTAIR contributes to the cisplatin-induced resistance in endometrial cancer cells
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Article
Impact of metabolic dysfunction-associated fatty liver disease on liver transplant recipients with hepatitis B virus-related hepatocellular carcinoma
Metabolic dysfunction-associated fatty liver disease was proposed by international consensus to redefine the metabolic abnormal condition. However, its impact on liver transplant recipients with hepatitis B vi...
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Article
Mechanism of high-energy pulsed current-assisted rolling of 08AL carbon steel ultra-thin strip
To improve the plastic deformation performance of a 08AL carbon steel ultra-thin strip, a pulsed electric field was integrated into the plastic processing of the ultra-thin strip, and the effects of high-energ...
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Article
Predicting Risk Stratification in Early-Stage Endometrial Carcinoma: Significance of Multiparametric MRI Radiomics Model
Endometrial carcinoma (EC) risk stratification prior to surgery is crucial for clinical treatment. In this study, we intend to evaluate the predictive value of radiomics models based on magnetic resonance imag...
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Article
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies
Extracellular matrix metalloproteinase inducer CD147 is a glycoprotein on the cell surface. There is minimal expression of CD147 in normal epithelial and fetal tissues, but it is highly expressed in a number o...
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Article
Potential protective effects of sodium butyrate on glycinin-induced oxidative stress, inflammatory response, and growth inhibition in Cyprinus carpio
Investigated mitigating effects of sodium butyrate (SB) on the inflammatory response, oxidative stress, and growth inhibition of common carp (Cyprinus carpio) (2.94 ± 0.2 g) are caused by glycinin. Six isonitroge...
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Article
Molecular Mechanism of Polysaccharides Extracted from Chinese Medicine Targeting Gut Microbiota for Promoting Health
The accumulating evidence revealed that gut microbiota plays an important role in pathological process of disease including obesity, type 2 diabetes mellitus, heart failure, and non-alcoholic fatty liver disea...
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Article
AMPK role in epilepsy: a promising therapeutic target?
Epilepsy is a complex and multifaceted neurological disorder characterized by spontaneous and recurring seizures. It poses significant therapeutic challenges due to its diverse etiology and often-refractory na...
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Article
Open AccessRetraction Note: MiR-125 family improves the radiosensitivity of head and neck squamous cell carcinoma
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Article
Open AccessCRP, IL-1α, IL-1β, and IL-6 levels and the risk of breast cancer: a two-sample Mendelian randomization study
Epidemiological studies have reported a positive association between chronic inflammation and cancer risk. However, the causal association between chronic inflammation and breast cancer (BC) risk remains uncle...
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Article
Open AccessHydrogen-bonded organic frameworks in solution enables continuous and high-crystalline membranes
Hydrogen-Bonded organic frameworks (HOFs) are a type of emerging porous materials. At present, little research has been conducted on their solution state. This work demonstrates that HOFs fragment into small p...
