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  1. Article

    Activation of synovial fibroblasts via Toll-like receptor signaling

    D Kyburz, M Pierer, J Rethage, R Seibl, RE Gay, DA Carson, S Gay in Arthritis Res Ther (2003)

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  2. Article

    Combination of cellular imaging and molecular analysis for evaluation of cellular gene therapy of RA

    IH Tarner, E Neumann, M Judex, J Schölmerich, S Gay, U Müller-Ladner in Arthritis Res Ther (2003)

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  3. Article

    Increased susceptibility of osteoarthritis tenocytes to FasL-induced apoptosis is associated with elevated expression of Fas receptor but no alterations in the expression of Sentrin-1/SUMO-1

    A Machner, A Baier, A Drynda, S Drynda, G Pap, S Gay, W Neumann… in Arthritis Res Ther (2003)

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    Article

    Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3

    Matrix metalloproteinases (MMPs) are believed to be pivotal enzymes in the invasion of articular cartilage by synovial tissue in rheumatoid arthritis (RA). Here, we investigated the effects of gene transfer of...

    W H van der Laan, P H A Quax, C A Seemayer, L G M Huisman, E J Pieterman… in Gene Therapy (2003)

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    Article

    Inhibition of cartilage destruction by double gene transfer of IL-1Ra and IL-10 involves the activin pathway

    The objective of the study was to determine the effects and the molecular background of interleukin-1 receptor antagonist (IL-1Ra) and vIL-10 double gene transfer into human synovial fibroblasts from patients ...

    E Neumann, M Judex, F Kullmann, J Grifka, P D Robbins, T Pap, R E Gay… in Gene Therapy (2002)

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    Article

    Chemokines and chemokine receptors in the pathogenesis of systemic sclerosis

     Activation of the immune system and increased synthesis of extracellular matrix proteins by fibroblasts are hallmarks in the pathogenesis of systemic sclerosis (SSc). The mechanisms that initiate the accumula...

    O. Distler, J. Distler, O. Kowal-Bielecka, R. E. Gay… in Modern Rheumatology (2002)

  7. Article

    Efficacy of retroviral gene transfer into synovial fibroblasts is reduced by co-transduction with adenoviral vectors

    U Müller-Ladner, O Distler, S Gay, E Neumann, M Judex… in Arthritis Research & Therapy (2002)

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  8. Article

    HIF-1 mediated upregulation of VEGF and VEGF-R in systemic sclerosis (SSc): Imbalance with angiostatic factors suggests VEGF as a novel option for the treatment of ischemia in patients with SSc

    O Distler, A Scheid, A Del Rosso, J Rethage, M Neidhart… in Arthritis Research & Therapy (2002)

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  9. Article

    Bacterial peptidoglycan stimulates integrin expression and MMP production of synovial fibroblasts

    DK Kyburz, J Rethage, R Seibl, BA Michel, RE Gay, DA Carson… in Arthritis Research & Therapy (2002)

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  10. Article

    Differential gene expression of proliferating synovial fibroblasts in rheumatoid arthritis

    KM Masuda, R Masuda, M Neidhart, BR Simmen, BA Michel… in Arthritis Research & Therapy (2002)

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  11. Article

    Expression of galectin-3 in rheumatoid arthritis synovium

    M Neidhart, S Kuchen, C Seemayer, RE Gay, BA Michel, S Gay in Arthritis Research & Therapy (2002)

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  12. Article

    Effects of TIMP-1 and TIMP-3 gene transfer on invasiveness, proliferation and apoptosis of rheumatoid arthritis (RA) synovial fibroblasts (RA-SF)

    T Pap, A Drynda, CA Seemayer, PHA Quax, JH Verheijen… in Arthritis Research & Therapy (2002)

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    Chapter

    Rolle der Zytokine bei der Progredienz der rheumatoiden Arthritis

    Mit rasanter Geschwindigkeit werden neue Informationen über die molekularen und zellulären „pathways“ der rheumatischen Erkrankungen erzielt. Die Anzahl der neu entdeckten Gensequenzen, die für neue Transkript...

    S. Gay, M. Neidhart, T. Pap… in Der IL-1-Rezeptor-Antagonist im Zytokin-Ne… (2002)

  14. Article

    Éjaculation provoquée par le vibromassage ou l’électrostimulation endorectale chez le blessé médullaire: injection intracytoplasmique de spermatozoïdes obtenus par stimulation endorectale chez neuf couples

    Moins de 15% des hommes avec une lésion complète de la moelle obtiennent une éjaculation lors de rapports sexuels ou de la masturbation. Le vibromassage du pénis permet d’obtenir une éjaculation pour au moins ...

    G. Egon, A. Scobai, A. L. Ferrapie, D. Domessent, P. Sigogneau, S. Gay in Andrologie (2001)

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    Article

    Die Rheumatoide Arthritis: Neuentwicklungen in der Pathogenese unter besonderer Berücksichtigung der synovialen Fibroblasten

    Die Pathophysiologie der rheumatoiden Arthritis (RA) ist durch eine synoviale Hyperplasie, pathologische Immunphänomene und eine progressive Gelenkzerstörung gekennzeichnet. Eine Vielzahl verschiedener Zellty...

    C. A. Seemayer, O. Distler, S. Kuchen, U. Müller-Ladner… in Zeitschrift für Rheumatologie (2001)

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    Article

    "Inverse wrap": an improved implantation technique for virus-transduced synovial fibroblasts in the SCID mouse model for rheumatoid arthritis

    The SCID mouse model for rheumatoid arthritis (RA) is an established and reliable approach to examining the distinct mechanisms operative in RA synovium, and evaluating novel gene therapy strategies. However,...

    M. Judex, E. Neumann, M. Fleck, T. Pap, J. D. Mountz, R. E. Gay… in Modern Rheumatology (2001)

  17. Article

    Transfer of protease inhibitors to inhibit cartilage destruction

    WH van der Laan, T Pap, PHA Quax, JM TeKoppele… in Arthritis Research & Therapy (2001)

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  18. Article

    Delivery of antisense constructs and ribozymes to inhibit cartilage destruction in the SCID mouse model of RA

    T Pap, J Schedel, U Müller-Ladner, RE Gay, W Zacharias… in Arthritis Research & Therapy (2001)

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  19. Article

    Double and triple gene transfer in arthritis

    U Müller-Ladner, E Neumann, M Fleck, T Pap, RE Gay… in Arthritis Research & Therapy (2001)

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  20. No Access

    Chapter

    Proteomics and Mass Spectrometry

    W. V. Bienvenut, M. Müller, P. M. Palagi… in Mass Spectrometry and Genomic Analysis (2001)

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