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Article
Open AccessMistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics
When processing microarray data sets, we recently noticed that some gene names were being changed inadvertently to non-gene names.
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Article
Comparing cDNA and oligonucleotide array data: concordance of gene expression across platforms for the NCI-60 cancer cells
Microarray gene-expression profiles are generally validated one gene at a time by real-time RT-PCR. We describe here a different approach based on simultaneous mutual validation of large numbers of genes using...
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Article
Open AccessMatchMiner: a tool for batch navigation among gene and gene product identifiers
MatchMiner is a freely available program package for batch navigation among gene and gene product identifier types commonly encountered in microarray studies and other forms of 'omic' research. The user inputs...
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Article
Open AccessGoMiner: a resource for biological interpretation of genomic and proteomic data
We have developed GoMiner, a program package that organizes lists of 'interesting' genes (for example, under- and overexpressed genes from a microarray experiment) for biological interpretation in the context ...
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Chapter
Lipid Model Membrane Studies on Immune Cytotoxic Mechanisms
The immune lysis of cells is thought to involve an initial breakdown of the membrane permeability barrier to small ions, with eventual colloid osmotic swelling and disruption of the cell. Lipid model membranes...