1,114 Result(s)
-
Article
Open AccessGenoMycAnalyzer: a web-based tool for species and drug resistance prediction for Mycobacterium genomes
Drug-resistant tuberculosis (TB) is a major threat to global public health. Whole-genome sequencing (WGS) is a useful tool for species identification and drug resistance prediction, and many clinical laborator...
-
Article
Open AccessFinely tuned ionizable lipid nanoparticles for CRISPR/Cas9 ribonucleoprotein delivery and gene editing
Nonviral delivery of the CRISPR/Cas9 system provides great benefits for in vivo gene therapy due to the low risk of side effects. However, in vivo gene editing by delivering the Cas9 ribonucleoprotein (RNP) is...
-
Article
Open AccessComparative analysis of malt quality and starch characteristics of three South Korean barley cultivars
In this study, malt was produced in pilot-scale facilities and conditioned using three barley (Hordeum vulgare L.) cultivars in South Korea (Heugho, Hopum, and Kwangmaeg). Quality and starch characteristics were ...
-
Article
Effects of alternative sweeteners with or without xanthan gum on the physicochemical properties of scone products
The physicochemical properties of scones made with alternative sweeteners (stevia, sucralose, and allulose) at different ratios (30, 70, and 100%) with or without xanthan gum were investigated. Nineteen sample...
-
Article
Open AccessAuthor Correction: Versatile spaceborne photonics with chalcogenide phase-change materials
-
Article
Open AccessA new model using deep learning to predict recurrence after surgical resection of lung adenocarcinoma
This study aimed to develop a deep learning (DL) model for predicting the recurrence risk of lung adenocarcinoma (LUAD) based on its histopathological features. Clinicopathological data and whole slide images ...
-
Article
Firm value, ownership structure, and strategic approaches to ESG activities
The strategic role of environmental, social, and governance (ESG) activities in firm performance has recently drawn increasing attention. In particular, the dynamics of ESG management in family-owned firms hav...
-
Article
Statistical analysis of discretely sampled semilinear SPDEs: a power variation approach
Motivated by problems from statistical analysis for discretely sampled SPDEs, first we derive central limit theorems for higher order finite differences applied to stochastic processes with arbitrary finitely ...
-
Article
Open AccessDysregulated CREB3 cleavage at the nuclear membrane induces karyoptosis-mediated cell death
Cancer cells often exhibit resistance to apoptotic cell death, but they may be vulnerable to other types of cell death. Elucidating additional mechanisms that govern cancer cell death is crucial for develo**...
-
Article
Dual suppressive effect of p-coumaric acid on pigmentation in B16F10 cells
Hyperpigmentation, frequently triggered by an excessive production of melanin, is a common issue within the realms of dermatology and cosmetology. In addition to regulating tyrosinase activity, the autophagy p...
-
Article
Open AccessVersatile spaceborne photonics with chalcogenide phase-change materials
Recent growth in space systems has seen increasing capabilities packed into smaller and lighter Earth observation and deep space mission spacecraft. Phase-change materials (PCMs) are nonvolatile, reconfigurabl...
-
Article
Modelling host–microbiome interactions in organ-on-a-chip platforms
The human microbiome orchestrates a variety of metabolic, immunological and regulatory functions in health and disease. However, experimentally dissecting host–microbiome interactions remains challenging. In t...
-
Article
Open AccessFLI-1 is expressed in a wide variety of hematolymphoid neoplasms: a special concern in the differential diagnosis
Friend Leukemia Virus Integration 1 (FLI-1) is a member of E26 transformation-specific family of transcription factors that participates in hematopoietic and vascular endothelial cell development. Immunohistoc...
-
Article
Open AccessMigraine is associated with the development of adult patients with inflammatory bowel disease: a nationwide, population-based study
It has been reported that migraine is more common in patients with inflammatory bowel disease (IBD) than in general. However, the impact of migraine on the development of IBD has not yet been elucidated. The a...
-
Article
Open AccessTRIM22 induces cellular senescence by targeting PHLPP2 in hepatocellular carcinoma
The ubiquitin-proteasome system is a vital protein degradation system that is involved in various cellular processes, such as cell cycle progression, apoptosis, and differentiation. Dysregulation of this syste...
-
Article
Open AccessPsychosocial Factors Associated with dizziness and chronic dizziness: a nationwide cross-sectional study
Dizziness is a common symptom in adults, and chronic dizziness, such as persistent postural-perceptual dizziness, is also frequently reported and affects the quality of life of patients. This study aimed to id...
-
Chapter and Conference Paper
Principal Component Analysis over the Boolean Circuit Within TFHE Scheme
In today’s information-driven world, the need to protect personal data while maintaining efficient data processing capabilities is crucial. Homomorphic Encryption (HE) has emerged as a potential solution, allo...
-
Article
Open AccessSpatial architectures of somatic mutations in normal prostate, benign prostatic hyperplasia and coexisting prostate cancer
This study aimed to identify somatic mutations in nontumor cells (NSMs) in normal prostate and benign prostatic hyperplasia (BPH) and to determine their relatedness to prostate cancer (PCA). From 22 PCA patien...
-
Article
Open AccessImpaired neuronal activity as a potential factor contributing to the underdeveloped cerebrovasculature in a young Parkinson’s disease mouse model
Misfolding of α-synuclein (α-Syn) in the brain causes cellular dysfunction, leading to cell death in a group of neurons, and consequently causes the progression of Parkinson’s disease (PD). Although many studi...
-
Article
Open AccessAuthor Correction: Multiparity increases the risk of diabetes by impairing the proliferative capacity of pancreatic β cells