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Article
Open AccessPrediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia: randomized trials and multiomics analysis
Choosing the appropriate antipsychotic drug (APD) treatment for patients with schizophrenia (SCZ) can be challenging, as the treatment response to APD is highly variable and difficult to predict due to the lac...
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Article
Open AccessRadiographic and α-fetoprotein response predict pathologic complete response to immunotherapy plus a TKI in hepatocellular carcinoma: a multicenter study
Pathologic complete response (pCR) following preoperative systemic therapy is associated with improved outcomes after subsequent liver transplant/resection in hepatocellular carcinoma (HCC). However, the relat...
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Article
Grape Seed Extract Attenuates Demyelination in Experimental Autoimmune Encephalomyelitis Mice by Inhibiting Inflammatory Response of Immune Cells
To examine the anti-inflammatory effect of grape seed extract (GSE) in animal and cellular models and explore its mechanism of action.
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Article
Open AccessPoricoic acid A suppresses renal fibroblast activation and interstitial fibrosis in UUO rats via upregulating Sirt3 and promoting β-catenin K49 deacetylation
Renal interstitial fibrosis is the common pathological process of various chronic kidney diseases to end-stage renal disease. Inhibition of fibroblast activation attenuates renal interstitial fibrosis. Our pre...
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Article
Effects of Surface Roughness on Interface Bonding Performance for 316H Stainless Steel in Hot-Compression Bonding
The metallurgical bonding quality of bonding joints is affected by the substrate surface state in hot-compression bonding (HCB), and the surface roughness is a core indicator of the surface state. However, the...
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Article
Prussian Blue/Cellulose Acetate Thin Film Composite Nanofiltration Membrane for Molecular Sieving and Catalytic Fouling Resistance
Nanofiltration (NF) membranes as high selective separators are appealing for molecular sieving, which still remains a great challenge for the mixed dyes with same charge. In this study, cellulose acetate (CA) ...
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Article
10-Hertz squeezed light source generation on the cesium D2 line using single photon modulation
Generation of squeezed light source is a promising technique to overcome the standard quantum limit in precision measurement. Here, we demonstrate an experimental generation of quadrature squeezing resonating ...
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Article
Open AccessMetavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes
The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcri...
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Chapter and Conference Paper
Characteristics and Main Controlling Factors of Giant Thick Lacustrine Carbonate Reservoirs of M Block
Block M is located in the A Basin, Brazil, and the main target layer is the Lower Cretaceous lacustrine carbonate rock. According to the data of cores, thin sections, logging and other data, the reservoir char...
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Chapter and Conference Paper
Proppant Combination Optimization and Flow Conductivity Research of Jimusaer Shale Oil
The proppant conductivity evaluation is mostly based on the water phase, but the average viscosity of Jimsar shale oil is 123.2 mpa·s, which is far higher than that of water. Therefore, the conductivity test w...
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Article
Open AccessTransition-metal free C–N bond formation from alkyl iodides and diazonium salts via halogen-atom transfer
Construction of C-N bond continues to be one part of the most significant goals in organic chemistry because of the universal applications of amines in pharmaceuticals, materials and agrochemicals. However, E2...
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Article
Naoxintong Capsule for Secondary Prevention of Ischemic Stroke: A Multicenter, Randomized, and Placebo-Controlled Trial
To examine whether the combination of Naoxintong Capsule with standard care could further reduce the recurrence of ischemic stroke without increasing the risk of severe bleeding.
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Article
Second-step lectotypification of the Linnaean name Artemisia dracunculus (Asteraceae-Anthemideae)
The lectotype sheet of the Linnaean name Artemisia dracunculus (Asteraceae-Anthemideae) was found to be mixed, containing two different taxa, A. dracunculus and A. glauca. Therefore, a second-step lectotypificati...
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Article
Open AccessIdentifying optimal candidates for postoperative adjuvant therapy among regional persistent/recurrent nasopharyngeal carcinoma patients after neck dissection
To analyze the clinical outcomes of patients with regional persistent/recurrent nasopharyngeal carcinoma (NPC) who received neck dissection, and to evaluate the clinical benefit of postoperative adjuvant thera...
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Article
Open AccessCorrection: Prefrontal cortex miR-29b-3p plays a key role in the antidepressant-like effect of ketamine in rats
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Article
Novel recombinant human thyroid-stimulating hormone in aiding postoperative assessment of patients with differentiated thyroid cancer—phase I/II study
Thyroid hormone withdrawal (THW) inevitably induced hypothyroidism in patients with differentiated thyroid cancer (DTC), and we aimed to evaluate the safety and efficacy of a novel recombinant human thyroid-st...
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Article
Tranexamic acid dosage for spinal surgery: a meta-analysis
We conducted this meta-analysis of randomized controlled trials (RCTs) to compare the efficacy of different doses of intravenous tranexamic acid (TXA) in spinal surgery.
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Article
Customized Non-uniform Discrete Variables Coordinated Optimization Coupling Nonlinear Mechanical Analysis on Complex Truss Structure
The use of nonlinear mechanical analysis in the optimization design process can achieve the precise numerical design of complex truss structures, which is a research hotspot and challenge in the field of struc...
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Article
Polarization-insensitive quantum key distribution using planar lightwave circuit chips
Self-stabilizing the quantum key distribution (QKD) system is essential to evaluate eavesdroppers’ information accurately. We develop and verify a polarization-insensitive time-bin decoder chip for QKD with th...
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Article
Open AccessPrognostic significance of AKR1C4 and the advantage of combining EBV DNA to stratify patients at high risk of locoregional recurrence of nasopharyngeal carcinoma
Distinguishing patients at a greater risk of recurrence is essential for treating locoregional advanced nasopharyngeal carcinoma (NPC). This study aimed to explore the potential of aldo–keto reductase 1C4 (AKR...
