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Article
An optimization method of trochoidal radius for trochoidal milling hole based on the adaptive feed rate scheduling
The machining time is mainly related to the tool path and the corresponding feed speed, while the trochoidal tool path depends on the trochoidal step and trochoidal radius. The material removal rate is periodi...
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Article
Open AccessDelineating the early dissemination mechanisms of acral melanoma by integrating single-cell and spatial transcriptomic analyses
Acral melanoma (AM) is a rare subtype of melanoma characterized by a high incidence of lymph node (LN) metastasis, a critical factor in tumor dissemination and therapeutic decision-making. Here, we employ sing...
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Article
Open AccessValidation of the Chinese version of academic goals orientation questionnaire in nursing student: a study based on SEM and IRT multidimensional models
To translate the Academic Goals Orientation Questionnaire (AGOQ) into Chinese and to determine the validity and reliability of the (AGOQ) in Chinese nursing students based on SEM and IRT multidimensional models.
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Article
Analysis of the relationship between lens morphology and aberrations in patients with myopia: a cross-sectional study
To investigate the relationship between lens morphology and aberrations in patients with myopia.
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Article
Fabrication of graphene-assisted voltammetry platform for the detection of nitrate ions in PM2.5
This study presents the fabrication and application of a graphene-assisted voltammetry platform for the sensitive detection of nitrate ions in PM2.5 (atmospheric aerosols with a maximum diameter of 2.5 µm). Th...
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Article
Experimental investigation of the microstructural evolution of weakly cemented sandstone under seepage erosion
The coal-bearing strata in the Ordos Basin, China, formed in the Jurassic, and the associated sandstone aquifer is characterized by a short diagenesis time and weak cementation. Affected by seepage erosion, in...
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Article
Research progress on high-value-added application of lignocellulosic biomass based on deep eutectic solvent pretreatment
As an emerging green solvent, deep eutectic solvent (DES) was widely used in the pretreatment and high-value-added transformation of lignocellulose due to its unique physical, chemical, and biological advantag...
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Article
Open AccessDevelopment and validation of the OSASH score to predict overall survival of hepatocellular carcinoma after surgical resection: a dual-institutional study
To develop and validate a risk score based on preoperative clinical-radiological parameters for predicting overall survival (OS) in patients undergoing surgical resection for hepatocellular carcinoma (HCC).
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Article
Open AccessDecoding the metastatic potential and optimal postoperative adjuvant therapy of melanoma based on metastasis score
Metastasis is a formidable challenge in the prognosis of melanoma. Accurately predicting the metastatic potential of non-metastatic melanoma (NMM) and determining effective postoperative adjuvant treatments fo...
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Article
Open AccessDirectional transport of drug droplets based on structural and wettability gradients on antibacterial Janus wound plaster with hemostatic, antiextravasation, and prehealing properties
The failure of wound healing is majorly attributed to uncontrolled bleeding and bacterial infections. However, develo** a wound plaster that can stop bleeding, resist blood extravasation, and realize directi...
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Article
Open AccessA study on the “community-hospital-community” model of community nursing practice teaching for undergraduate nursing students
To improve the quality of community nursing teaching practice and cultivate undergraduate nursing students who meet the quality accreditation standards of our nursing profession, and to explore the establishme...
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Article
A novel ensemble model using artificial neural network for predicting wave-induced forces on coastal bridge decks
Due to the effects of climate change, coastal engineering structures are more vulnerable to the wave forces caused by natural hazards, especially for low-lying bridges. To facilitate the structural design and ...
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Article
Open AccessPrediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma
Melanoma is the deadliest form of skin tumor, and G protein-coupled receptors (GPCRs) play crucial roles in its carcinogenesis. Furthermore, the tumor microenvironment (TME) affects the overall survival (OS) a...
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Article
Open AccessFNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1
Regenerative therapy based on mesenchymal stem cells (MSCs) has great promise to achieve functional recovery in cerebral infarction patients. However, the survival rate of transplanted MSCs is extremely low be...
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Article
A circular waste bioeconomy development model in the Ecuadorian fishery industry: the impact of government strategy on supply chain integration and smart operations
This study develops a set of measures to address the interrelationship among circular waste-based bioeconomy (CWBE) attributes, including those of government strategy, digital collaboration, supply chain integ...
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Article
Ultra-low-frequency radio astronomy observations from a Seleno-centric orbit
This paper introduces the first results of observations with the Ultra-Long-Wavelength (ULW) —- Low Frequency Interferometer and Spectrometer (LFIS) on board the selenocentric satellite Longjiang-2. We present a ...
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Article
Design optimization of plastic scintillators with wavelength-shifting fibers and silicon photomultiplier readouts in the top veto tracker of the JUNO-TAO experiment
Plastic scintillators (PSs) embedded with wavelength-shifting fibers are widely used in high-energy particle physics, such as in muon taggers, as well as in medical physics and other applications. In this stud...
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Article
Leap of Li Metal Anodes from Coin Cells to Pouch Cells: Challenges and Progress
Li metal anodes have attracted tremendous attention in the last decade because of their high theoretical capacities and low electrochemical potentials. However, until now, there has only been limited success i...
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Article
Molecular recognition of two endogenous hormones by the human parathyroid hormone receptor-1
Parathyroid hormone (PTH) and PTH-related peptide (PTHrP) are two endogenous hormones recognized by PTH receptor-1 (PTH1R), a member of class B G protein- coupled receptors (GPCRs). Both PTH and PTHrP analogs ...
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Article
Open AccessLZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway
LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unk...
