33 Result(s)

Article

LRP4 is required for the olfactory association task in the piriform cortex

Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, ...

Min Yan, Mingtao **ong, Yongqiang Wu, Dong Lin, Peng Chen, Jiang Chen… in Cell & Bioscience (2022)

Article

Activating Parkin-dependent mitophagy alleviates oxidative stress, apoptosis, and promotes random-pattern skin flaps survival

The random-pattern skin flap is a crucial technique in reconstructive surgery and flap necrosis caused by ischemia/reperfusion injury is a major postoperative complication. Herein, we investigated the mechanis...

Zhengtai Chen, Hongqiang Wu, Jianxin Yang, Baolong Li, Jian Ding… in Communications Biology (2022)

Article

Peripheral immune cell profiling of double-hit lymphoma by mass cytometry

Double-hit or Triple-hit lymphoma (DHL/THL) is a subset of high-grade B cell lymphoma harboring rearrangements of MYC and BCL2 and/or BCL6, and usually associate with aggressive profile, while current therapies t...

Tao Lei, Gongqiang Wu, Yong** Xu, Weihao Zhuang, Jialiang Lu, Shuiyun Han… in BMC Cancer (2023)

Article

Identification of mitochondrial respiratory chain signature for predicting prognosis and immunotherapy response in stomach adenocarcinoma

Stomach adenocarcinoma (STAD) is the third leading cause of cancer-related deaths and the fifth most prevalent malignancy worldwide. Mitochondrial respiratory chain complexes play a crucial role in STAD pathog...

**g Yang, Feifan **, Huanjuan Li, Yuhuan Shen, Weilin Shi… in Cancer Cell International (2023)

Article

High-quality chromosome-level de novo assembly of the Trifolium repens

White clover (Trifolium repens L.), an excellent perennial legume forage, is an allotetraploid native to southeastern Europe and southern Asia. It has high nutritional, ecological, genetic breeding, and medicinal...

Hongjie Wang, Yongqiang Wu, Yong He, Guoyu Li, Lichao Ma, Shuo Li… in BMC Genomics (2023)

Article

Stromal cells in the tumor microenvironment: accomplices of tumor progression?

The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular component), and cellular components include cancer cells and non-malignant cells such as immune cells and stromal cel...

Yan Zhao, Meili Shen, Liangqiang Wu, Haiqin Yang, Yixuan Yao… in Cell Death & Disease (2023)

Article

Tyrosine-kinase inhibitor combined with iodine-125 seed brachytherapy for hepatocellular carcinoma refractory to transarterial chemoembolization: a propensity-matched study

To investigate the efficacy and safety of tyrosine-kinase inhibitor (TKI) combined with iodine-125 seed brachytherapy (TKI-I) versus TKI alone for patients with hepatocellular carcinoma (HCC) refractory to tra...

Yongjian Guo, **gqiang Wu, Licong Liang, Kangshun Zhu, **gwen Zhou… in Cancer Imaging (2023)

Article

Author Correction: Research on Homogeneity and Service Performance under the Liquid Core Forging Process

Yongqiang Wu, Yongshan Wang, Kaikun Wang… in Metallography, Microstructure, and Analysis (2023)

Article

Evaluation of the efficacy of Biejia decoction pill combined with entecavir in the treatment of hepatitis B liver fibrosis/cirrhosis by VCTE

The vibration controlled transient elastography (VCTE) technique was used to assess the effectiveness of a Biejia Decoction pill in combination with Entecavir in the treatment of hepatitis B liver fibrosis/cir...

Lijun Wan, Chungen Hu, Fenfen Wang, Kedong Xu, Fan Li, Bo He… in Scientific Reports (2023)

Article

DTX2 promotes glioma development via regulation of HLTF

Human Deltex 2 (DTX2) is a ubiquitin E3 ligase that functions as an oncogene and has been shown to participate in many human cancers. However, the role of DTX2 in glioma progression has remained obscure. In th...

Ren Li, Yang Chen, Biao Yang, Ziao Li, Peize Li, Yu Chen, Jiayu Li… in Biology Direct (2024)

Article

Safety and feasibility of anti-CD19 CAR T cells expressing inducible IL-7 and CCL19 in patients with relapsed or refractory large B-cell lymphoma

Although CD19-specific chimeric antigen receptor (CAR) T cells are curative for patients with relapsed or refractory large B-cell lymphoma (R/R LBCL), disease relapse with tumor antigen-positive remains a chal...

Wen Lei, Ai Zhao, Hui Liu, Chunmei Yang, Cheng Wei, Shanshan Guo… in Cell Discovery (2024)

Article

Screening and verification of hub genes in esophageal squamous cell carcinoma by integrated analysis

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors. However, the mechanisms underlying ESCC tumorigenesis have not been fully elucidated. Thus, we aimed to determine the key g...

Hongqiang Wu, Peiyao Zhu, Peng Shu, Shuguang Zhang in Scientific Reports (2024)

Article

Identification of metabolism-related key genes as potential biomarkers for pathogenesis of immune thrombocytopenia

Immune thrombocytopenia (ITP), an acquired autoimmune disease, is characterized by immune-mediated platelet destruction. A biomarker is a biological entity that contributes to disease pathogenesis and reflects...

**angmei Xu, Jiamin Zhang, Hongyun **ng, Liying Han, **aoming Li… in Scientific Reports (2024)