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  1. Article

    Open Access

    HOXD3 targeted by miR-203a suppresses cell metastasis and angiogenesis through VEGFR in human hepatocellular carcinoma cells

    Hepatocellular carcinoma (HCC), one of the most common aggressive tumors worldwide has a relatively high mortality rate among malignant tumors. MicroRNAs (miRNAs), acting as tumor suppressors, are involved in ...

    Lumin Wang, Dongdong Tong, Qingqing Guo, **aofei Wang, Fei Wu in Scientific Reports (2018)

  2. Article

    Open Access

    Evaluation of animal-to-human and human-to-human transmission of influenza A (H7N9) virus in China, 2013–15

    A novel avian-origin influenza A(H7N9) virus emerged in China in March 2013 and by 27 September 2017 a total of 1533 laboratory-confirmed cases have been reported. Occurrences of animal-to-human and human-to-h...

    Victor Virlogeux, Luzhao Feng, Tim K. Tsang, Hui Jiang, Vicky J. Fang in Scientific Reports (2018)

  3. Article

    Open Access

    Transcriptomic profiling of Alternaria longipes invasion in tobacco reveals pathogenesis regulated by AlHK1, a group III histidine kinase

    Tobacco brown spot, caused by Alternaria species, is a devastating tobacco disease. To explore the role of a group III histidine kinase (AlHK1) on A. longipes pathogenesis, the invasion progress of A. longipes wa...

    Juan Yang, Zhi-Qun Yin, Zi-Teng Kang, Chen-Jian Liu, **-Kui Yang in Scientific Reports (2017)

  4. Article

    Open Access

    Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A

    Rare ent-abietane-rosane diterpenoid heterodimers, Bisebracteolasins A and B (1 and 2, respectively), were isolated from the roots of Euphorbia ebracteolata Hayata. Their structures and absolute configurations we...

    Wen-Juan Yuan, **ao Ding, Zhe Wang, Bi-Juan Yang, **ao-Nian Li in Scientific Reports (2017)

  5. Article

    Open Access

    Selective binding of choline by a phosphate-coordination-based triple helicate featuring an aromatic box

    In nature, proteins have evolved sophisticated cavities tailored for capturing target guests selectively among competitors of similar size, shape, and charge. The fundamental principles guiding the molecular r...

    Chuandong Jia, Wei Zuo, Dong Yang, Yanming Chen, Li** Cao in Nature Communications (2017)

  6. Article

    Open Access

    Lipid levels and new-onset diabetes in a hypertensive population: the China Stroke Primary Prevention Trial

    This study aimed to provide insights into the relationship between lipid levels and new-onset diabetes (NOD) in 14,864 Chinese hypertensive patients without diabetes (6056 men and 8808 women) aged 45–75 years ...

    Leliang Li, ** Li, Juan Yang, **ao Huang, Huihui Bao, Chunyan Zhang in Scientific Reports (2017)

  7. Article

    Open Access

    Utilization of a Wheat660K SNP array-derived high-density genetic map for high-resolution map** of a major QTL for kernel number

    In crop plants, a high-density genetic linkage map is essential for both genetic and genomic researches. The complexity and the large size of wheat genome have hampered the acquisition of a high-resolution gen...

    Fa Cui, Na Zhang, **ao-li Fan, Wei Zhang, Chun-hua Zhao, Li-juan Yang in Scientific Reports (2017)

  8. Article

    Open Access

    Serum glycopattern and Maackia amurensis lectin-II binding glycoproteins in autism spectrum disorder

    The pathophysiology of autistic spectrum disorder (ASD) is not fully understood and there are no diagnostic or predictive biomarkers. Glycosylation modified as many as 70% of all human proteins can sensitively...

    Yannan Qin, Yanni Chen, Juan Yang, Fei Wu, Lingyu Zhao, Fuquan Yang in Scientific Reports (2017)

  9. Article

    Open Access

    Effects of drought on leaf carbon source and growth of European beech are modulated by soil type

    Drought potentially affects carbon balance and growth of trees, but little is known to what extent soil plays a role in the trade-off between carbon gain and growth investment. In the present study, we analyze...

    Jian-Feng Liu, Matthias Arend, Wen-Juan Yang, Marcus Schaub in Scientific Reports (2017)

  10. Article

    Open Access

    Aortic arch calcification and risk of cardiovascular or all-cause and mortality in dialysis patients: A meta-analysis

    Studies on aortic arch calcification (AAC) and mortality risk in maintenance dialysis patients have yielded conflicting findings. We conducted this meta-analysis to investigate the association between the pres...

    Ao Zhang, Shiji Wang, Hongxiang Li, Juan Yang, Hui Wu in Scientific Reports (2016)

  11. Article

    Open Access

    Sanguisorba officinalis L synergistically enhanced 5-fluorouracil cytotoxicity in colorectal cancer cells by promoting a reactive oxygen species-mediated, mitochondria-caspase-dependent apoptotic pathway

    Sanguisorba officinalis L. radix is a widely used herb called DiYu (DY) in China and has an extensive range of bioactivities, including anti-cancer, anti-inflammatory, and anti-oxidative activities. However, ther...

    Meng-** Liu, Min Liao, Cong Dai, Jie-feng Chen, Chun-juan Yang in Scientific Reports (2016)

  12. Article

    Open Access

    Identification of novel serum peptide biomarkers for high-altitude adaptation: a comparative approach

    We aimed to identify serum biomarkers for screening individuals who could adapt to high-altitude hypoxia at sea level. HHA (high-altitude hypoxia acclimated; n = 48) and HHI (high-altitude hypoxia illness; n = 48...

    Juan Yang, Wenhua Li, Siyuan Liu, Dongya Yuan, Yijiao Guo, Cheng Jia in Scientific Reports (2016)

  13. Article

    Open Access

    Trait self-esteem and neural activities related to self-evaluation and social feedback

    Self-esteem has been associated with neural responses to self-reflection and attitude toward social feedback but in different brain regions. The distinct associations might arise from different tasks or task-r...

    Juan Yang, **aofan Xu, Yu Chen, Zhenhao Shi, Shihui Han in Scientific Reports (2016)

  14. Article

    Open Access

    Synthesis and antitumor activity of novel N-substituted carbazole imidazolium salt derivatives

    A series of novel N-substituted carbazole imidazolium salt derivatives has been prepared and investigated for their cytotoxic activity against five human tumor cell lines by MTS assay. The results indicated that ...

    Lan-**ang Liu, Xue-Quan Wang, Bei Zhou, Li-Juan Yang, Yan Li in Scientific Reports (2015)

  15. Article

    Open Access

    Latency of auditory evoked potential monitoring the effects of general anesthetics on nerve fibers and synapses

    Auditory evoked potential (AEP) is an effective index for the effects of general anesthetics. However, it’s unknown if AEP can differentiate the effects of general anesthetics on nerve fibers and synapses. Pre...

    Bowan Huang, Feixue Liang, Lei Zhong, Minlin Lin, Juan Yang in Scientific Reports (2015)

  16. Article

    Open Access

    Heralded Quantum Entanglement between Distant Matter Qubits

    We propose a scheme to realize heralded quantum entanglement between two distant matter qubits using two Λ atom systems. Our proposal does not need any photon interference. We also present a general theory of ...

    Wen-Juan Yang, **ang-Bin Wang in Scientific Reports (2015)

  17. Article

    Open Access

    Re-annotation of presumed noncoding disease/trait-associated genetic variants by integrative analyses

    Using RefSeq annotations, most disease/trait-associated genetic variants identified by genome-wide association studies (GWAS) appear to be located within intronic or intergenic regions, which makes it difficul...

    Geng Chen, Dianke Yu, Jiwei Chen, Ruifang Cao, Juan Yang, Huan Wang in Scientific Reports (2015)

  18. No Access

    Article

    Chirality-specific growth of single-walled carbon nanotubes on solid alloy catalysts

    Single-walled carbon nanotubes of a single chirality can be produced with an abundance of more than 92 per cent when using tungsten-based bimetallic alloy nanocrystals as catalysts.

    Feng Yang, **ao Wang, Daqi Zhang, Juan Yang, Da Luo, Ziwei Xu, Jiake Wei in Nature (2014)

  19. Article

    Open Access

    Diameter-controlled growth of aligned single-walled carbon nanotubes on quartz using molecular nanoclusters as catalyst precursors

    Molecular nanoclusters containing Fe and Mo atoms have been used as catalyst precursors for the growth of single-walled carbon nanotubes (SWNTs) on stable temperature (ST)-cut quartz substrates by chemical vap...

    Fei Peng, Da Luo, Hao Sun, **Yong Wang, Feng Yang, RuoMing Li in Chinese Science Bulletin (2013)

  20. Article

    Open Access

    Deposition of bio-mimicking graphene sheets with lotus leaf-like and cell-like structures on the nickel substrate

    Bio-mimicking graphene films, deposited on textured nickel substrates, were synthesized by the following method: replicating the surface textures of the lotus leaf by polymer duplication, fabricating textured ...

    Juan Yang, **ngBin Yan, Ying Wang, BaoMin Luo, Li** Wang in Chinese Science Bulletin (2012)

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