8,449 Result(s)
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Article
Distribution of glutamate-like and glutamine-like immunoreactivities in the rat organ of Corti: a light microscopic and semiquantitative electron microscopic analysis with a note on the localization of aspartate
The light- and electron microscopic localization of glutamate and glutamine in the rat organ of Corti was studied by means of antisera raised against the respective amino acids coupled to carrier proteins. The...
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Article
Effects of the triazole derivative loreclezole (R72063) on stimulus induced ionic and field potential responses and on different patterns of epileptiform activity induced by low magnesium in rat entorhinal cortex-hippocampal slices
Effects of loreclezole (R72063), a triazole derivative with anticonvulsant properties, were studied on field potentials in rat hippocampal slices and on different patterns of low Mg2+-induced epileptiform activit...
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Article
Somatostatin concentrations in cerebrospinal fluid and brain tissue of patients with refractory epilepsy
The somatostatin concentrations of cerebrospinal fluid (CSF) and brain tissue in 16 refractory epileptic patients were measured simultaneously by a radioimmunoassay (RIA) method. An increased level of somatost...
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Article
Immunocytochemical staining with antibodies against protein kinase C and its isozymes in the turtle retina
An LM immunocytochemical study has investigated the patterns of staining in turtle retina with monoclonal antibodies to the α, β and γ isozymes of protein kinase C. The protein kinase C-γ antibody reveals cell...
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Article
Expression of neuropeptides and neuropeptide mRNAs in spinal cord after axotomy in the rat, with special reference to motoneurons and galanin
The extent to which the plasticity in peptide expression observed in develo** spinal motoneurons occurs following proximal peripheral axotomy in the adult rat was examined using in situ hybridization and imm...
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Article
Characterization of the angiotensin II-receptor subtype in the longitudinal smooth muscle of the rat portal vein
The purpose of the present study was to identify the angiotensin II-receptor subtype involved in the enhancement of the amplitude of the phasic contractions by angiotensin II in the isolated rat portal vein pr...
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Article
Effect of peripheral nerve cut on neuropeptides in dorsal root ganglia and the spinal cord of monkey with special reference to galanin
Using the indirect immunofluorescence method andin situ hybridization, the localization and levels of immunoreactivities and mRNAs for several neuropeptides were studied in lumbar dorsal root ganglia and spinal c...
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Article
Magnetoencephalography using high temperature rf SQUIDs
We have developed high-critical-temperature radio-frequency Super conducting QUantum Interference Devices (SQUIDs) with step-edge grain-boundary Josephson junctions and large flux focusers. These planar device...
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Article
Positive inotropic action of angiotensin II in the pithed rat
The cardiovascular effects of angiotensin II were examined in aortic blood pressure-controlled and-uncontrolled pithed rats. Angiotensin II induced a dose-dependent increase in diastolic blood pressure, left v...
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Article
The ciliary ganglion of the cat: a light and electron microscopic study
The ciliary ganglia of eight healthy adult cats were studied by light and electron microscopy. The ganglion, measuring about 2 mm in length, was consistently found to be attached to the branch from the oculomo...
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Article
The competition of (−)-[3H]nicotine binding by the enantiomers of nicotine, nornicotine and anatoxin-a in membranes and solubilized preparations of different brain regions of rat
In order to characterize the properties of nicotinic acetylcholine receptor (nAChR) subtypes in the CNS, the enantiomers of nicotine, nornicotine and anatoxin-a were studied for their ability to displace (−)-[3H]...
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Article
Upper cervical inspiratory neurons in the rat: an electrophysiological and morphological study
Upper cervical inspiratory neurons form a distinct neuronal column located near the lateral edge of the intermediate grey matter in the rostral spinal segments. Previous studies conducted in cats have demonstr...
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Article
Nicotinic cholinoceptor-mediated excitatory postsynaptic potentials in rat nucleus ambiguus
In rat brainstem slice preparations, intracellular recording from neurons (n = 39) in the compact formation of the nucleus ambiguus (AMBc) revealed spontaneous and miniature excitatory postsynaptic potentials (EP...
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Article
Whole-cell recording of the Ca2+-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions
Using the whole-cell recording technique, we have examined the slow Ca2+-activated afterhyperpolarization (AHP) and its underlying current (I AHP) in hippocampal CA1 neurones of brain slices obtained from mature ...
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Article
Electrophysiological evidence for the presence of an apical H+-ATPase in Malpighian tubules of Formica polyctena: intracellular and luminal pH measurements
Cellular and luminal pH of isolated ant Malpighian tubules were measured in different bath K+ concentrations using double-barrelled pH microelectrodes. The electrochemical gradient for H+ across the basolateral a...
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Article
A functional role for nitric oxide in locus coeruleus: immunohistochemical and electrophysiological studies
Immunohistochemical analysis of the localization of nitric oxide synthase-(NOS)-like immunoreactivity revealed the presence of this enzyme in a few neuronal cell bodies and in dendritic and axonal processes wi...
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Article
Prolonged inhibition of brain nitric oxide synthase by short-term systemic administration of nitro-l-arginine methyl ester
We studied the dose-response characteristics and the temporal profile of inhibition of brain nitric oxide (NO) synthase (NOS) elicited by i.v. administration of the NOS inhibitor nitro-l-arginine methyl ester (L-...
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Article
Calcium dependency of the AT1-receptor mediated effects in the rat portal vein: influence of calcium antagonists
The calcium dependency of AT1-receptor mediated contractions was studied in isolated rat portal vein preparations.
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Article
Inhibitory effect of dithiothreitol on angiotensin II-induced contractions mediated by AT1-receptors in rat portal vein and rabbit aorta
The disulfide-reducing agent dithiothreitol (DTT) has been shown to reduce angiotensin II (Ang II) subtype 1 receptor (AT,) binding sites in various tissues. Its effect on Ang II-induced contractions was studi...
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Article
Insidious errors in dipole parameters due to shell model misspecification using multiple time-points
Insidious errors in dipole modeling due to shell model misspecification in a spherical model were examined analyzing multiple time-points using the constraints of a commonly-used DSL (Dipole Source Localizatio...
