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Article
Association between obstructive sleep apnea severity and depression risk: a systematic review and dose-response meta-analysis
Obstructive sleep apnea (OSA) has received considerable attention as a potential risk factor for depressive symptoms. The systematic review was conducted to confirm the dose‒response connection between OSA sev...
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Article
Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents
The age of onset of hypertension (HTN) is decreasing, and obesity is a significant risk factor. The prevalence and racial disparities in pediatric HTN and the association between body composition and blood pre...
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Article
Development and validation of a novel non-invasive test for diagnosing nonalcoholic fatty liver disease in Chinese children
With the exploding prevalence of obesity, many children are at risk of develo** nonalcoholic fatty liver disease. Using anthropometric and laboratory parameters, our study aimed to develop a model to quantit...
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Article
Open AccessThe role of nutrition in analysis of risk factors and short-term outcomes for late-onset necrotizing enterocolitis among very preterm infants: a nationwide, multicenter study in China
Necrotizing enterocolitis (NEC) is a serious gastrointestinal disease, primarily affects preterm newborns and occurs after 7 days of life (late-onset NEC, LO-NEC). Unfortunately, over the past several decades,...
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Article
Open AccessAssociations of maternal serum concentration of iron-related indicators with birth outcomes in Chinese: a pilot prospective cohort study
Previous studies of maternal iron and birth outcomes have been limited to single indicators that do not reflect the comprehensive relationship with birth outcomes. We aimed to investigate the relationship betw...
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Article
Pachyonychia Congenita
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Article
Diagnosis, treatment and prevention of severe acute respiratory syndrome coronavirus 2 infection in children: experts’ consensus statement updated for the Omicron variant
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Article
Open AccessCorrection to: Expert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children
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Article
Continuous age- and sex-specific reference ranges of liver enzymes in Chinese children and application in pediatric non-alcoholic fatty liver disease
Alanine aminotransferase (ALT) is widely used to screen patients with hepatic diseases. However, the current reference ranges (< 50 U/L) were developed by laboratories and have not been validated in population...
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Article
Open AccessClinical impact and in vitro characterization of ADNP variants in pediatric patients
Helsmoortel–Van der Aa syndrome (HVDAS) is a rare genetic disorder caused by variants in the activity-dependent neuroprotector homeobox (ADNP) gene; hence, it is also called ADNP syndrome. ADNP is a multitasking ...
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Article
Open AccessIncreased expression of NLRP3 associated with elevated levels of HMGB1 in children with febrile seizures: a case–control study
High mobility group box-1 (HMGB1) is an endogenous danger signal that mediates activation of the innate immune response including NLR pyrin domain containing 3 (NLRP3) inflammasome activation and proinflammato...
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Article
Correction to: Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents
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Article
Open AccessExpert consensus on the diagnosis, treatment, and prevention of respiratory syncytial virus infections in children
Respiratory syncytial virus (RSV) is the leading global cause of respiratory infections and is responsible for about 3 million hospitalizations and more than 100,000 deaths annually in children younger than 5 ...
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Current Mycoplasma pneumoniae epidemic among children in Shanghai: unusual pneumonia caused by usual pathogen
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Open AccessPrognostic factors for intermediate- or high-risk neuroblastomas in children in China
Evidence regarding the characteristics and prognosis of neuroblastoma (NBL) in China is limited. We aimed to investigate the characteristics and prognosis of intermediate- or high-risk NBL in children in China.
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Article
Clinical analysis of 2790 children with retinoblastoma: a single-center experience in China
In this study, we aimed to analyze the clinical characteristics and prognosis of children with retinoblastoma (RB) in a single center in China with a large sample collection spanning 17 years.
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Article
Open AccessInteractions between long interpregnancy interval and advanced maternal age on neonatal outcomes
After the implementation of the universal two-child policy in China, it was more frequent to have long interpregnancy intervals (IPIs) and advanced maternal age. However, the interactions between long IPIs and...
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Article
Open AccessReal-world evidence regarding the growth of very premature infants with small for gestational age after birth: a multicenter survey in China
To analyze the real-world growth pattern of very premature infants (VPI) with small for gestational age (SGA) after birth by using the ΔZ value of weight at discharge.
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Article
Open AccessCan radiomics be used to detect hypoxic–ischemic encephalopathy in neonates without magnetic resonance imaging abnormalities?
No study has assessed normal magnetic resonance imaging (MRI) findings to predict potential brain injury in neonates with hypoxic–ischemic encephalopathy (HIE).
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Article
Diagnosis, treatment, and prevention of monkeypox in children: an experts’ consensus statement
Monkeypox is a zoonotic disease. Since the first human monkeypox case was detected in 1970, it has been prevalent in some countries in central and western Africa. Since May 2022, monkeypox cases have been repo...