994 Result(s)

Article

Human serum albumin-based drug-free macromolecular therapeutics induce apoptosis in chronic lymphocytic leukemia patient cells by crosslinking of CD20 and/or CD38 receptors

This study explores the efficacy of human serum albumin (HSA)-based Drug-Free Macromolecular Therapeutics (DFMT) in treating Chronic Lymphocytic Leukemia (CLL), a prevalent adult leukemia subtype. DFMT, a nove...

Jiahui Li, M. Tommy Gambles, Brandt Jones… in Drug Delivery and Translational Research (2024)

Article

HDAC1 Promotes Mitochondrial Pathway Apoptosis and Inhibits the Endoplasmic Reticulum Stress Response in High Glucose-Treated Schwann Cells via Decreased U4 Spliceosomal RNA

Dysfunction of Schwann cells, including cell apoptosis, autophagy inhibition, dedifferentiation, and pyroptosis, is a pivotal pathogenic factor in induced diabetic peripheral neuropathy (DPN). Histone deacetyl...

Tingting **, Ziming Wang, Fan Fan, Wandi Wei, Chenming Zhou… in Neurochemical Research (2024)

Article

Prenatal Inflammatory Exposure Predisposes Offspring to Chronic Kidney Diseases Via the Activation of the eIF2α-ATF4 Pathway

It has recently become more recognized that renal diseases in adults can originate from adverse intrauterine (maternal) environmental exposures. Previously, we found that prenatal lipopolysaccharide (LPS) expo...

Jie Liu, **n Chen, Jie Liu, Cui** Peng, Fangjie Wang, **aoyong Huang… in Inflammation (2024)

Article

Colorectal cancer screening: results from the World Trade Center Health Registry cohort

Little is known about colorectal cancer screening in 9/11 World Trade Center (WTC)-exposed populations. We utilized survey data from the WTC Health Registry (WTCHR) to examine associations between enrollees’ c...

Hannah M. Thompson, Janette Yung, Jiehui Li, James Cone in Cancer Causes & Control (2024)

Article

Qualitative and Quantitative Analysis of Three-Dimensional Fluorescence Spectra by Improved Parallel Factor Analysis with Internal Standard Sample Embedding

The strategy of parallel factor analysis, combined with the internal standard method, has been increasingly applied to the qualitative and quantitative analysis of three-dimensional fluorescence spectra of unk...

Hubin Liu, Li Zhang, Guimin Cai, Zhixiang Zhang, Jiachen Li… in Journal of Fluorescence (2024)

Article

Seedling root system adaptation to water availability during maize domestication and global expansion

The maize root system has been reshaped by indirect selection during global adaptation to new agricultural environments. In this study, we characterized the root systems of more than 9,000 global maize accessi...

Peng Yu, Chunhui Li, Meng Li, **aoming He, Danning Wang, Hongjie Li… in Nature Genetics (2024)

Article

Resveratrol ameliorates DSS-induced ulcerative colitis by acting on mouse gut microbiota

Ulcerative colitis (UC) is a multi-faceted, recurrent immune disorder caused by dextran sulfate sodium (DSS). The intestinal microbiota has multiple functions in the host, so UC requires long-term potent medic...

Bing Yu, Ying Wang, Zekai Tan, Zhengyi Hong, Lewen Yao… in Inflammopharmacology (2024)

Article

Donkey-like kirkovirus is associated with diarrhea in piglets

Kirkovirus (kirV), a seemingly novel virus family, has been found in horses and donkeys. The study’s objectives are to investigate the presence of the virus in swine. In this study, donkey-like kirV was detect...

Panpan Tong, Zunbao Wang, Yueyi Dang, Lei Zhang, Guangwei Song… in Virus Genes (2024)

Article

Effect of the CYBA C242T Polymorphism on Preeclampsia Pathogenesis in the Chinese Population

Although the mechanisms responsible for the pathogenesis of preeclampsia (PE) have not been entirely clarified, oxidative stress is thought to be its leading cause. As a major component responsible for reactiv...

Ru Zhang, Shuhui Liu, ** Tan, Zihan Guo, Huabin Hou, Shiguo Liu… in Biochemical Genetics (2024)

Article

UDPG: Maintaining the true nature of sugar

Ronghui Yang, Binghui Li in Cellular & Molecular Immunology (2024)

Article

Fluoxetine Successfully Treats Intracranial Enterovirus E18 Infection in a Patient with CD79a Deficiency Arising from Segmental Uniparental Disomy of Chromosome 19

The pre BCR complex plays a crucial role in B cell production, and its successful expression marks the B cell differentiation from the pro-B to pre-B. The CD79a and CD79b mutations, encoding Igα and Igβ respec...

Lang Yu, Yishi Zhang, Wenhui Li, **xiao Mao, Yulin Li… in Journal of Clinical Immunology (2024)

Article

PRDX1 Interfering Peptide Disrupts Amino Acids 70–90 of PRDX1 to Inhibit the TLR4/NF-κB Signaling Pathway and Attenuate Neuroinflammation and Ischemic Brain Injury

Ischemic stroke ranks among the leading causes of death and disability in humans and is accompanied by motor and cognitive impairment. However, the precise mechanisms underlying injury after stroke and effecti...

**ang-Yu Ma, Cheng-yu Qi, **ng-yi Xu, Hui Li, Chang-Dong Liu… in Molecular Neurobiology (2024)

Article

EVA1A reverses lenvatinib resistance in hepatocellular carcinoma through regulating PI3K/AKT/p53 signaling axis

Lenvatinib is a commonly used first-line drug for the treatment of advanced hepatocellular carcinoma (HCC). However, its clinical efficacy is limited due to the drug resistance. EVA1A was a newly identified tu...

**aokun Liu, **ao Gao, Yuling Yang, Di Yang, Qingming Guo, Lianhui Li… in Apoptosis (2024)

Article

Multiclass motor imagery classification with Riemannian geometry and temporal-spectral selection

Motor imagery (MI) based brain-computer interfaces (BCIs) decode the users’ intentions from electroencephalography (EEG) to achieve information control and interaction between the brain and external devices. I...

Zhaohui Li, **aohui Tan, **nyu Li… in Medical & Biological Engineering & Computi… (2024)