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Atmospheric Pressure Plasma Therapy for Wound Healing and Disinfection: A Review

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Wound Healing Research

Abstract

In the past two decades, usage of non-thermal, cold atmospheric pressure (CAP) plasmas for medical application are widely studied as it can be used at room temperature and pressures without damaging the human skin. There are a lot of prospective applications of CAP plasma in various health-related applications like wound healing, cancer treatment, disinfection, dental, and many others. Cold atmospheric plasma has been explored for its use in dermatology, particularly for wound disinfection and as a curative remedy for skin diseases caused by pathogens, due to its antimicrobial properties. The cellular mechanisms involved in CAP plasma for wound healing have been well studied. Various plasma-based sources for wound healing have been developed. In this chapter, in the beginning, a brief overview of plasma and plasma sources along with its interaction with living cells is presented. In vitro and in vivo investigations for wound disinfection by various researchers along with clinical trials for wound healing have also been summarized. As this technology is novel, a lot of research and clearances are yet to be obtained for the medical community to be convinced of its safety and efficiency compared to the traditional and conventional therapeutic methods for wound healing.

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Authors and Affiliations

  1. Institute for Plasma Research (IPR), Gandhinagar, Gujarat, India

    Alphonsa Joseph, Ramkrishna Rane & Akshay Vaid

  2. Homi Bhabha National Institute, Mumbai, Maharashtra, India

    Alphonsa Joseph

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  1. Alphonsa Joseph
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  2. Ramkrishna Rane
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  3. Akshay Vaid
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Correspondence to Alphonsa Joseph .

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  1. Department of Chemical Engineering, Chungbuk National University, Cheongju, Korea (Republic of)

    Prasun Kumar

  2. Institute of Science, Nirma University, Ahmedabad, India

    Vijay Kothari

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Joseph, A., Rane, R., Vaid, A. (2021). Atmospheric Pressure Plasma Therapy for Wound Healing and Disinfection: A Review. In: Kumar, P., Kothari, V. (eds) Wound Healing Research. Springer, Singapore. https://doi.org/10.1007/978-981-16-2677-7_19

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