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Acid-Base Physiology and Pathophysiology

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Contemporary Nephrology

Abstract

In the past 2 years a considerable amount of new data has been introduced in acidbase physiology, to a large degree because of the emergence of technology for fluorometric measurement of intracellular pH. While fluorescence techniques have blossomed, the last 2 years witnessed very few studies performed with classic micropuncture, clearance, or balance techniques. Another major trend is the shift of interest to aspects of cell biology, including mechanisms of cell pH regulation and the roles of intracellular and extracellular messengers. Finally, the loudest discussions occurred regarding the role of urea metabolism in overall acid-base balance, despite the fact that few new data were produced in regard to the question.

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  1. Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, 79430, USA

    Melvin E. Laski & Neil A. Kurtzman

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  1. Melvin E. Laski
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  1. Washington University School of Medicine, St. Louis, Missouri, USA

    Saulo Klahr M.D.

  2. University of Southern California School of Medicine, Los Angeles, California, USA

    Shaul G. Massry M.D.

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© 1989 Plenum Publishing Corporation

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Laski, M.E., Kurtzman, N.A. (1989). Acid-Base Physiology and Pathophysiology. In: Klahr, S., Massry, S.G. (eds) Contemporary Nephrology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0829-4_4

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