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Surface Modification of Biomedical Scaffolds by Plasma Treatment

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Abstract

The effects of plasma treatment on the surface roughness and hydrophility of polymer materials used as biodegradable scaffolds (polylactide films, sponges, and nonwoven fibrous sheets) have been studied. Two methods have been used for quantitative estimation of changes: three-dimensional reconstruction of the scaffold surfaces using scanning electron microscopy (SEM) and BET physical adsorption analysis. Proceeding from the experimental results, it is established that plasma treatment forms nano- and micropits on the sample surface and thus increases its hydrophility (moreover, the surface morphology can be varied by changing the treatment duration). It is shown that plasma treatment is an efficient method for controlled increase in the roughness of polymer materials, which can lead to enhancement of adhesion and proliferation of cells.

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Funding

This study was supported by the Russian Science Foundation (grant no. 21-13-00321 “Deformation Behavior of Various Biodegradable Scaffolds under Mechanical Load”).

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Authors and Affiliations

  1. National Research Centre “Kurchatov Institute”, 123182, Moscow, Russia

    E. V. Yastremsky, T. D. Patsaev, A. A. Mikhutkin, R. V. Sharikov, R. A. Kamyshinsky, K. I. Lukanina, N. A. Sharikova, T. E. Grigoriev & A. L. Vasiliev

  2. Shubnikov Institute of Crystallography, Federal Scientific Research Centre “Crystallography and Photonics,” Russian Academy of Sciences, 119333, Moscow, Russia

    E. V. Yastremsky, R. A. Kamyshinsky & A. L. Vasiliev

  3. Moscow Institute of Physics and Technology (State University), 141701, Dolgoprudny, Moscow region, Russia

    A. L. Vasiliev

Authors
  1. E. V. Yastremsky
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  2. T. D. Patsaev
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  3. A. A. Mikhutkin
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  4. R. V. Sharikov
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  5. R. A. Kamyshinsky
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  6. K. I. Lukanina
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  7. N. A. Sharikova
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  8. T. E. Grigoriev
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  9. A. L. Vasiliev
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Correspondence to A. L. Vasiliev.

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Translated by Yu. Sin’kov

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Yastremsky, E.V., Patsaev, T.D., Mikhutkin, A.A. et al. Surface Modification of Biomedical Scaffolds by Plasma Treatment. Crystallogr. Rep. 67, 421–427 (2022). https://doi.org/10.1134/S1063774522030233

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  • DOI: https://doi.org/10.1134/S1063774522030233

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