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Protein-rich tryptic soy broth biomaterial for improving solid polymer electrolyte lithium-ion battery performance
Aiming toward sustainable, economic, safe, and environmentally friendly energy storage, biomaterials and bio-inspired designs are increasingly...
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Silver nanoparticle toxicity on Artemia parthenogenetica nauplii hatched on axenic tryptic soy agar solid medium
The use of gnobiotic brine shrimp ( Artemia spp.) for ecotoxicology and bacteria-host interaction studies is common. However, requirements for axenic...
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The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII
Due to the limited effects of conventional antibiotics on the increasing emergence of drug-resistant bacteria and fungi, novel antimicrobial agents...
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Human Hepatic Transporter Signature Peptides for Quantitative Targeted Absolute Proteomics: Selection, Digestion Efficiency, and Peptide Stability
PurposeQuantitative targeted absolute proteomics (QTAP) quantifies proteins by measuring the signature peptides produced from target proteins by...
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Bottom-Up Analysis of Proteins by Peptide Mass Fingerprinting with tCITP-CZE-ESI-TOF MS After Tryptic Digest
The identification of proteins in samples of moderate to complex composition is primarily done by bottom-up approaches. Therefore, proteins are...
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Immobilized enzyme microreactors for analysis of tryptic peptides in β-casein and β-lactoglobulin
In this study, our primary objective was to develop an effective analytical method for studying trypsin-digested peptides of two proteins commonly...
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Tryptic Stability and Antimicrobial Activity of the Derivatives of Polybia-CP with Fine-Tuning Modification in the Side Chain of Lysine
Antimicrobial peptides (AMPs) were believed to be a class of promising antimicrobials to combat the increasing resistant microbes. However, AMPs...
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The stability of Staphylococcal bacteriophage in presence of local vancomycin concentrations used in clinical practice
PurposeTo evaluate the stability of a clinically used Staphylococcal bacteriophage with doses of vancomycin that are encountered with local...
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In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution
Protein stability is an essential property for biological function. In contrast to the vast knowledge on protein stability in vitro, little is known...
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Long-term stability of aerophilic metallic surfaces underwater
Aerophilic surfaces immersed underwater trap films of air known as plastrons. Plastrons have typically been considered impractical for underwater...
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Engineering stringent genetic biocontainment of yeast with a protein stability switch
Synthetic biology holds immense promise to tackle key problems in resource use, environmental remediation, and human health care. However,...
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Stability of enzyme immobilized on the nanofluidic channel surface
The lifetime of an enzyme is critical to prevent system failure and optimize maintenance schedules in biological and analytical chemistry. The...
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Impact of C- and N-terminal protection on the stability, metal chelation and antimicrobial properties of calcitermin
The main limitation to the use of antimicrobial peptides (AMPs) as regular drugs, against antibiotic and antifungal resistance, mainly relates to...
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Modeling study of long-term stability of the monoclonal antibody infliximab and biosimilars using liquid-chromatography–tandem mass spectrometry and size-exclusion chromatography–multi-angle light scattering
Monoclonal antibodies (mAbs) represent a dynamic class of biopharmaceutical products, as evidenced by an increasing number of market authorizations...
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Tuning phenylalanine fluorination to assess aromatic contributions to protein function and stability in cells
The aromatic side-chains of phenylalanine, tyrosine, and tryptophan interact with their environments via both hydrophobic and electrostatic...
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Cefoperazone rapidly and sensitive quantitative assessment via a validated RP-HPLC method for different dosage forms, in-use stability, and antimicrobial activities
Cefoperazone (Cfz) is a member of the third generation of parenteral cephalosporin antibiotics. It is used on a wide scale in prescribed antibiotic...
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Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15
DNA replication and repair defects or genotoxic treatments trigger interferon (IFN)-mediated inflammatory responses. However, whether and how IFN...
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RACK1 facilitates breast cancer progression by competitively inhibiting the binding of β-catenin to PSMD2 and enhancing the stability of β-catenin
The receptor for activated C kinase 1 (RACK1) is a key scaffolding protein with multifunctional and multifaceted properties. By mediating...
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Peptidylarginine deiminase 2 plays a key role in osteogenesis by enhancing RUNX2 stability through citrullination
Peptidylarginine deiminase (PADI) 2 catalyzes the post-translational conversion of peptidyl-arginine to peptidyl-citrulline in a process called...
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Novel hydroxyapatite nanoparticle-based antibiotic alternative to combat methicillin-resistant S. aureus: A mechanism by targeting the structural and functional stability of MRSA membrane protein
In order to overcome the growing bacterial resistance, increasing effective and efficient utilization of antibiotics or the development of newer...
