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EsmTemp - Transfer Learning Approach for Predicting Protein Thermostability
Protein thermostability is one of the most important features of bio-engineered proteins with significant scientific and industrial applications....
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Forster Resonance Energy Transfer (FRET) to Visualize Protein–Protein Interactions in the Plant Cell
Forster resonance energy transfer (FRET) is an efficient method to visualize the protein–protein interaction in living cells. This technique is based...
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Measuring Protein–Protein Interactions in Cells using Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET) Assay
Protein–protein interactions (PPIsProtein-protein interactions (PPIs)) are increasingly recognized for their roles in functional cellular networks...
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LVPocket: integrated 3D global-local information to protein binding pockets prediction with transfer learning of protein structure classification
BackgroundPrevious deep learning methods for predicting protein binding pockets mainly employed 3D convolution, yet an abundance of convolution...
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Electron transfer in protein modifications: from detection to imaging
Signal pathways participate in vital biological processes and regulate complex life activities through protein modifications. Protein modifications...
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Photophysical Properties of Indotricarbocyanine Dyes Complexed with Lipid-Transfer Protein Ns-LTP1
The interaction of indotricarbocyanine dyes with lipid-transfer protein Ns-LTP1 in Dulbecco's phosphate-buffered saline (PBS) was studied. An...
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Cross-protein transfer learning substantially improves disease variant prediction
BackgroundGenetic variation in the human genome is a major determinant of individual disease risk, but the vast majority of missense variants have...
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Deep transfer learning for inter-chain contact predictions of transmembrane protein complexes
Membrane proteins are encoded by approximately a quarter of human genes. Inter-chain residue-residue contact information is important for structure...
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Discovery of novel cholesteryl ester transfer protein (CETP) inhibitors by a multi-stage virtual screening
Cholesteryl ester transfer protein (CETP) is a promising therapeutic target for cardiovascular diseases. It effectively lowers the low-density...
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Subcellular Protein Patterns Classification Using Extreme Gradient Boosting with Deep Transfer Learning as Feature Extractor
Proteins are essential structural and functional components of human cells. Understanding and identifying proteins can provide valuable insights into...
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C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia
High serum levels of triglycerides (TG) and low levels of high-density lipoprotein cholesterol (HDL-C) increase the risk of coronary heart disease in...
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Structure-based mechanism and inhibition of cholesteryl ester transfer protein
Purpose of ReviewCholesteryl ester transfer proteins (CETP) regulate plasma cholesterol levels by transferring cholesteryl esters (CEs) among...
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KT-AMP: Enhancing Antimicrobial Peptide Functions Prediction Through Knowledge Transfer on Protein Language Model
As the overuse of antibiotics enhances the resistance of various microbial pathogens to antibiotics, antimicrobial peptides (AMPs) have the potential...
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Protein–Protein Interactions: Co-immunoprecipitation
Proteins often do not function as single substances but rather as team players in a dynamic network. Growing evidences show that protein–protein...
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Lipid Transfer Protein Genes Are Differently Expressed in Rat Soleus Muscle at Early and Later Periods of Muscle Disuse
AbstractThis work reports analysis of lipid transfer protein (LTPs) mRNA levels in rat soleus muscle after 12-h and 14-day hindlimb suspension (HS)....
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Roles of peripheral lipoproteins and cholesteryl ester transfer protein in the vascular contributions to cognitive impairment and dementia
This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to...
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Selection of red fluorescent protein for genetic labeling of mitochondria and intercellular transfer of viable mitochondria
The phenomenon of intercellular mitochondrial transfer has attracted great attention in various fields of research, including stem cell biology....
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Resonance Energy Transfer
One way that an excited molecule can return to the ground state is to transfer the excitation energy to another molecule. This process, resonance...
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Studying Protein–Protein Interactions at Plasmodesmata by Measuring Förster Resonance Energy Transfer
Plasmodesmata (PD) provide interconnectivity between plant cells to enable the intercellular transport and communication that is requisite to...
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Measuring Protein-Protein Interactions of Melatonin Receptors by Bioluminescence Resonance Energy Transfer (BRET)
The melatonin receptor subfamily belongs to the G protein-coupled receptor superfamily and consists of three members in mammals, MT1, MT2, and GPR50....