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Antiviral activity of ouabain against a Brazilian Zika virus strain
Zika virus (ZIKV) is an emerging arbovirus associated with neurological disorders. Currently, no specific vaccines or antivirals are available to...
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Fluorinated 2-arylchroman-4-ones and their derivatives: synthesis, structure and antiviral activity
A number of new biologically interesting fluorinated 2-arylchroman-4-ones and their 3-arylidene derivatives were synthesized based on the p -toluenesul...
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Antiviral Activity of Technologically Processed Antibodies to CD4 Receptor against Influenza Infection
The antiviral activity of technologically processed antibodies to CD4 receptor was evaluated a model of sublethal A/California/04/2009...
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Antiviral activity of marine sulfated glycans against pathogenic human coronaviruses
Great interest exists towards the discovery and development of broad-spectrum antivirals. This occurs due to the frequent emergence of new viruses...
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Identification of herbal teas and their compounds eliciting antiviral activity against SARS-CoV-2 in vitro
BackgroundThe SARS-CoV-2/COVID-19 pandemic has inflicted medical and socioeconomic havoc, and despite the current availability of vaccines and broad...
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Synthesis of indole-based ferulic acid derivatives and in vitro evaluation of antiviral activity against SARS-CoV-2
The search for an effective small molecule against the severe acute respiratory syndrome related coronavirus 2 (SARS-CoV-2) is a challenge that...
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A conformational rearrangement of the SARS-CoV-2 host protein sigma-1 is required for antiviral activity: insights from a combined in-silico/in-vitro approach
The development of effective drugs to treat coronavirus infections remains a significant challenge for the scientific community. Recent evidence...
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Developments in Computer-Aided Drug Design for Antiviral Research
Computer-aided drug design (CADD) is a powerful tool for the rational design of new antivirals, allowing for the optimization of drug candidates... -
Exploring azomethine ylides reactivity with acrolein through cycloaddition reaction and computational antiviral activity assessment against hepatitis C virus
ContextThe regioselectivity and diastereoselectivity of the 1,3-dipolar cycloaddition reaction between azomethine ylides and acrolein were...
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Characterization and optimization of exopolysaccharide extracted from a newly isolated halotolerant cyanobacterium, Acaryochloris Al-Azhar MNE ON864448.1 with antiviral activity
Several antiviral agents lost their efficacy due to their severe side effects and virus mutations. This study aimed to identify and optimize the...
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Antiviral activity of nano-monocaprin against Phi6 as a surrogate for SARS-CoV-2
The COVID-19 pandemic involving SARS-CoV-2 has raised interest in using antimicrobial lipid formulations to inhibit viral entry into their host cells...
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Drug Resistance in Antiviral Therapy
Drug resistance in antiviral therapy is a major public health challenge. This resistance can occur among immunocompromised patients where persistent... -
New Antiviral Agent for Influenza: Baloxavir
It is estimated that a billion cases of influenza occur each year globally and that three to five million are serious infections with annual... -
Biofunctional Textiles: Functional Polymer-Carriers with Antiviral, Antibacterial, Antifungal, and Repellent Activity
In recent years, constant innovations have led to the applications of textile biotech, biomaterials, biotechnologies, and environmentally friendly... -
Diverse Glycosides from Gardenia latifolia with Antiviral Activity and Chemosystematic Significance
Several influenza pandemics have impacted our life, each with variable prevalence and severity. In a search for natural antivirals, further...
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Functional foods with antiviral activity
Viruses are known to cause a variety of diseases, ranging from mild respiratory diseases, such as the common cold, to fatal illnesses. Although the...
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Antiviral Activities of Cannabis
Despite the history of scientific evidence regarding plants and their products in prophylactics and therapeutics, their applications in healthcare... -
Alpha-sitosterol: a new antiviral agent produced by Streptomyces misakiensis and its potential activity against Newcastle disease virus
BackgroundNewcastle Disease Virus (NDV) causes severe economic losses in the poultry industry worldwide. Hence, this study aimed to discover a novel...
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Synthesis and antioxidant, antimicrobial, and antiviral activity of some pyrazole-based heterocycles using a 2(3H)-furanone derivative
Some pyrazole-based heterocycles such as pyrrolone, pyridazinone, and imidazole derivatives were synthesized utilizing the pyrazolyl-2(3 H )-furanone...
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Synthesis of N-heterocyclic amides based on (+)-camphoric acid and study of their antiviral activity and pharmacokinetics
Efficient conditions for the synthesis of nitrogen-containing heterocyclic derivatives of (1 R ,3 S )(+)-camphoric acid were selected. A series of...