Search
Search Results
-
Traditional Chinese Medicine and renal regeneration: experimental evidence and future perspectives
Repair of acute kidney injury (AKI) is a typical example of renal regeneration. AKI is characterized by tubular cell death, peritubular capillary...
-
ACSF2 and lysine lactylation contribute to renal tubule injury in diabetes
AimsLactate accumulation is reported to be a biomarker for diabetic nephropathy progression. Lactate drives lysine lactylation, a newly discovered...
-
Sex differences in renal transporters: assessment and functional consequences
Mammalian kidneys are specialized to maintain fluid and electrolyte homeostasis. The epithelial transport processes along the renal tubule that match...
-
Evaluation of proximal tubule functions in children with COVID-19: a prospective analytical study
BackgroundThere are limited numbers of studies focusing on renal effects of coronavirus disease 2019 (COVID-19) infection and proximal tubular...
-
Correlation between albuminuria and interstitial injury marker reductions associated with SGLT2 inhibitor treatment in diabetic patients with renal dysfunction
BackgroundWe investigated the effects of sodium–glucose cotransporter 2 inhibitor (SGLT2i) administration focusing on its involvement in...
-
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis
ObjectiveDiagnosis of immunoglobulin A nephropathy (IgAN) requires the evaluation of renal biopsy specimens. However, renal biopsy is an invasive...
-
Sodium glucose cotransporter 2 inhibitor suppresses renal injury in rats with renal congestion
Renal congestion is an issue of cardiorenal syndrome in patients with heart failure. Recent clinical and basic studies suggest a renoprotective...
-
The pathophysiology of distal renal tubular acidosis
The kidneys have a central role in the control of acid–base homeostasis owing to bicarbonate reabsorption and production of ammonia and ammonium in...
-
A renal aplasia case mimicking radiologically as unilateral renal agenesis in a child with spina bifida, atresia ani and unilateral undescended testis: a case report
BackgroundAs a result of the failure of embryogenic kidney formation, a condition can occur where not a single kidney appears and this phenomenon is...
-
ZNF692 promotes the migration and response to immunotherapy of clear cell renal cell carcinoma cells by targeting metabolic pathway
Clear cell renal cell carcinoma (ccRCC), with high mortality and poor prognosis, is the most common type of renal malignancy. It is necessary to...
-
Ipsilateral synchronous papillary renal neoplasm with reverse polarity and urothelial carcinoma in a renal transplant recipient: a rare case report with molecular analysis and literature review
BackgroundRenal transplant recipients (RTRs) have a 3- to 5-fold higher risk of develo** malignant tumors than the general population, with new...
-
Kangxianling formula attenuates renal fibrosis by regulating gut microbiota
BackgroundRenal fibrosis (RF) produced adverse effect on kidney function. Recently, intestinal dysbiosis is a key regulator that promotes the...
-
Physiological principles underlying the kidney targeting of renal nanomedicines
Kidney disease affects more than 10% of the global population and is associated with considerable morbidity and mortality, highlighting a need for...
-
Urinary citrate as a marker of renal function in patients with autosomal dominant polycystic kidney disease
IntroductionAutosomal dominant polycystic kidney disease (ADPKD) is frequent to find low urinary citrate levels. Recently, it has been suggested that...
-
Renal effects of SGLT2 inhibitors in cardiovascular patients with and without chronic kidney disease: focus on heart failure and renal outcomes
The kidney has a prominent role in maintaining glucose homeostasis by using glucose as a metabolic substrate. This occurs by generating glucose...
-
Effect of high density lipoprotein cholesterol (HDL-C) on renal outcome in patients with nephrotic syndrome complicated with steroid-induced diabetes mellitus(SIDM)
ObjectiveWe aimed to investigate the renal prognosis of patients with idiopathic nephrotic syndrome (INS) complicated with steroid-induced diabetes...
-
Renal tubular necrosis associated with anagrelide administration: a case report
A 62-year-old female patient with essential thrombocythemia experienced rapid renal dysfunction and was subsequently referred to our hospital....
-
Role of the Renal Lymphatic System in Heart Failure
Purpose of ReviewThe lymphatic system plays a major but overlooked role in maintaining fluid homeostasis. Given the unique fluid homeostasis...
-
Ocular manifestations of renal ciliopathies
Renal ciliopathies are a common cause of kidney failure in children and adults, and this study reviewed their ocular associations. Genes affected in...
-
Drug toxicity in the proximal tubule: new models, methods and mechanisms
The proximal tubule (PT) reabsorbs most of the glomerular filtrate and plays an important role in the uptake, metabolism and excretion of...
