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Translation, cross-cultural adaptation and measurement proprieties of the German version of the Allodynia Symptom Checklist (ASC-12)
BackgroundCutaneous allodynia is highly prevalent among migraineurs and is associated with a poor prognosis. The Allodynia Symptom Checklist (ASC-12)...
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Cutaneous allodynia as predictor for treatment response in chronic migraine: a cohort study
BackgroundCentral sensitisation is an important mechanism in migraine chronification. It is presumed to occur in second and third order neurons...
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Endophilin A2 controls touch and mechanical allodynia via kinesin-mediated Piezo2 trafficking
BackgroundTactile and mechanical pain are crucial to our interaction with the environment, yet the underpinning molecular mechanism is still elusive....
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Neurovascular Compression-Induced Intracranial Allodynia May Be the True Nature of Migraine Headache: an Interpretative Review
Purpose of ReviewSurgical deactivation of migraine trigger sites by extracranial neurovascular decompression has produced encouraging results and...
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Loss of lumbar disc height with age and its impact on pain and sensitivity associated behaviors in mice
PurposeAging is a risk factor for several debilitating conditions including those related to chronic back pain and intervertebral disc degeneration,...
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The outcome of polyethylene glycol fusion augmented by electrical stimulation in a delayed setting of nerve repair following neurotmesis in a rat model
PurposePolyethylene glycol is known to improve recovery following its use in repair of acute peripheral nerve injury. The duration till which PEG...
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Protective Mechanism of Electroacupuncture on Peripheral Neurotoxicity Induced by Oxaliplatin in Rats
ObjectiveTo study the effect of electroacupuncture (EA) on oxaliplatin-induced peripheral neuropathy (OIPN) in rats.
MethodsMale Sprague-Dawley rats...
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Does pain intensity after total knee arthroplasty depend on somatosensory functioning in knee osteoarthritis patients? A prospective cohort study
The objective of this study is to determine whether the change in pain intensity over time differs between somatosensory functioning evolution...
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Pain mechanisms in complex regional pain syndrome: a systematic review and meta-analysis of quantitative sensory testing outcomes
BackgroundComplex regional pain syndrome (CRPS) is a chronic condition following inciting events such as fractures or surgeries with sensorimotor and...
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Clinical usefulness of quantitative thermal sensory testing in the diagnosis and surgical treatment of women with pudendal neuropathy
BackgroundThe aim of this study, conducted on women with pudendal neuropathy, was to evaluate the usefulness of quantitative thermal sensory testing...
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Time-dependent photobiomodulation management of neuropathic pain induced by spinal cord injury in male rats
Neuropathic pain (NP) following spinal cord injury (SCI) often lasts for a long time and causes a range of problems that reduce the quality of life....
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TRPM8 genetic variant is associated with chronic migraine and allodynia
BackgroundMany single nucleotide polymorphisms (SNPs) have been reported to be associated with migraine susceptibility. However, evidences for their...
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Protective effects of Labisia pumila against neuropathy in a diabetic rat model
PurposeDiabetes accelerates peripheral, distal symmetric polyneuropathy, small fiber predominant neuropathy, radiculoplexopathy, and autonomic...
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Neuropeptide Y in the medial habenula alleviates migraine-like behaviors through the Y1 receptor
BackgroundMigraine is a highly disabling health burden with multiple symptoms; however, it remains undertreated because of an inadequate...
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Shank2 identifies a subset of glycinergic neurons involved in altered nociception in an autism model
BackgroundAutism Spectrum Disorders (ASD) patients experience disturbed nociception in the form of either hyposensitivity to pain or allodynia. A...
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Recent advances in our understanding of the organization of dorsal horn neuron populations and their contribution to cutaneous mechanical allodynia
The dorsal horns of the spinal cord and the trigeminal nuclei in the brainstem contain neuron populations that are critical to process sensory...
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Danggui Sini decoction alleviates oxaliplatin-induced peripheral neuropathy by regulating gut microbiota and potentially relieving neuroinflammation related metabolic disorder
BackgroundDanggui Sini decoction (DSD), a traditional Chinese medicine formula, has the function of nourishing blood, warming meridians, and...
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Pre- and post-headache phases of migraine: multi-country results from the CaMEO – International Study
BackgroundIndividuals with migraine frequently experience pre- and post-headache symptoms. This analysis aimed to characterize the relative frequency...
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Compromised trigemino-coerulean coupling in migraine sensitization can be prevented by blocking beta-receptors in the locus coeruleus
BackgroundMigraine is a disabling neurological disorder, characterized by recurrent headaches. During migraine attacks, individuals often experience...
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Excess abdominal fat is associated with cutaneous allodynia in individuals with migraine: a prospective cohort study
ObjectiveTo investigate the specific relationship between cutaneous allodynia (CA) and the percentages of body fat (BF) and abdominal fat in...
