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  1. Almond miRNA Expression and Horticultural Implications

    From the past, till now various improved almond cultivars with desired traits have been introduced through breeding programs based on classical and...
    Marzieh Karimi, Marjan Jafari, ... Behrouz Shiran in The Almond Tree Genome
    Chapter 2023
  2. Determining miRNA Expression Patterns in Xenopus

    Whole-mount in situ hybridization (WISH) is a technique that enables temporal and spatial visualization of RNA molecules in an embryo or whole tissue...
    Marco Antonaci, Alice M. Godden, Grant N. Wheeler in MicroRNA Detection and Target Identification
    Protocol 2023
  3. Evaluation of miRNA Expression in 3D In Vitro Scaffold-Based Cancer Models

    Accumulating experimental evidence suggests that 3D in vitro cancer models strengthen our understanding of vital processes in the tumor...
    Catherine Murphy, Ciara Gallagher, Olga Piskareva in MicroRNA Profiling
    Protocol 2023
  4. An Efficient CRISPR-Cas9 Method to Knock Out MiRNA Expression in Xenopus Tropicalis

    In recent years CRISPR-Cas9 knockouts (KO) have become increasingly utilized to study gene function. MicroRNAs (miRNAs) are short noncoding RNAs,...
    Alice M. Godden, Marco Antonaci, Grant N. Wheeler in MicroRNA Detection and Target Identification
    Protocol 2023
  5. Human umbilical cord-derived mesenchymal stromal cells improve myocardial fibrosis and restore miRNA-133a expression in diabetic cardiomyopathy

    Background

    Diabetic cardiomyopathy (DCM) is a serious health-threatening complication of diabetes mellitus characterized by myocardial fibrosis and...

    Boxin Liu, Yan Wei, ... Timothy O’Brien in Stem Cell Research & Therapy
    Article Open access 24 April 2024
  6. A preliminary study of the miRNA restitution effect on CNV-induced miRNA downregulation in CAKUT

    Background

    The majority of CAKUT-associated CNVs overlap at least one miRNA gene, thus affecting the cellular levels of the corresponding miRNA. We...

    Kristina Mitrovic, Ivan Zivotic, ... Ivan Jovanovic in BMC Genomics
    Article Open access 27 February 2024
  7. Bioinformatics Analysis of miRNA Sequencing Data

    The bioinformatics analysis of miRNA is a complicated task with multiple operations and steps involved from processing of raw sequence data to...
    Hrishikesh A. Lokhande in MicroRNA Profiling
    Protocol 2023
  8. Changes in miRNA expression in the lungs of pigs supplemented with different levels and forms of vitamin D

    Background

    Vitamin D is an immunomodulator, and its effects have been linked to many diseases, including the pathogenesis of cancer. However, the...

    Alicja Wierzbicka, Klaudia Pawlina-Tyszko, ... Maria Oczkowicz in Molecular Biology Reports
    Article Open access 12 December 2023
  9. Systematic analyzing a five- miRNA panel and its diagnostic value of plasma expression in colorectal cancer

    Background

    Aberrant expression of miRNAs have been implicated in cancers, but the role of miRNAs in colorectal cancer (CRC) remains need to be...

    Si-Qi Li, Li-Ye **e, ... Shu-Fang Ning in Molecular Biology Reports
    Article 07 July 2023
  10. iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes

    Recently, we reported that forkhead box A2 (FOXA2) is required for the development of human pancreatic α- and β-cells. However, whether miRNAs play a...

    Noura Aldous, Ahmed K. Elsayed, ... Essam M. Abdelalim in Stem Cell Reviews and Reports
    Article Open access 07 February 2023
  11. Maize—Azospirillum brasilense interaction: accessing maize’s miRNA expression under the effect of an inhibitor of indole-3-acetic acid production by the plant

    MicroRNA (miRNA) is a class of non-coding RNAs. They play essential roles in plants’ physiology, as in the regulation of plant development, response...

    Eliandro Espindula, Luciane Maria Pereira Passaglia in Brazilian Journal of Microbiology
    Article 12 January 2024
  12. Comprehensive analysis of the expression profiles of mRNA, lncRNA, circRNA, and miRNA in primary hair follicles of coarse sheep fetal skin

    Background

    The Qinghai Tibetan sheep, a local breed renowned for its long hair, has experienced significant deterioration in wool characteristics due...

    Dehong Tian, Quanbang Pei, ... Kai Zhao in BMC Genomics
    Article Open access 07 June 2024
  13. A comprehensive pan-cancer analysis reveals cancer-associated robust isomiR expression landscapes in miRNA arm switching

    MicroRNAs (miRNAs), important regulators of gene expression, play critical roles in various biological processes and tumorigenesis. To reveal the...

    Li Guo, Dekang Ren, ... Tingming Liang in Molecular Genetics and Genomics
    Article 23 February 2023
  14. Comparative analysis of miRNA expression profiles in flowering and non-flowering tissue of Crocus sativus L

    Crocus sativus is a valuable plant due to the presence of apocarotenoids in its stigma. Considerable work has been done in the past to understand the...

    Archana Bhat, Sonal Mishra, ... Manoj Kumar Dhar in Protoplasma
    Article 10 February 2024
  15. Association between Yili goose sperm motility and expression profiles of mRNA and miRNA in testis

    Background

    The study was conducted to find out the candidate microRNA (miRNA) and genes that associated with sperm motility of Yili goose through...

    Ying** Wu, Lihua Zhang, ... Ling Wang in BMC Genomics
    Article Open access 24 October 2023
  16. Identification of lncRNA, miRNA and mRNA expression profiles and ceRNA Networks in small cell lung cancer

    Background

    Small cell lung cancer (SCLC) is a highly lethal malignant tumor. It accounts for approximately 15% of newly diagnosed lung cancers. Long...

    Chenxi Zhang, Ying Zhou, ... **aoyuan Wu in BMC Genomics
    Article Open access 25 April 2023
  17. Plastid retrograde regulation of miRNA expression in response to light stress

    Background

    MicroRNAs (miRNAs) are a class of endogenous noncoding RNAs that play a pivotal role in the regulation of plant development and responses...

    Anna Barczak-Brzyżek, Grzegorz Brzyżek, ... Marcin Filipecki in BMC Plant Biology
    Article Open access 26 March 2022
  18. High-Temperature-Induced Differential Expression of miRNA Mediates Liver Inflammatory Response in Tsinling Lenok Trout (Brachymystax lenok tsinlingensis)

    High-temperature stress poses a significant environmental challenge for aquatic organisms, including tsinling lenok trout ( Brachymystax lenok...

    **aobin **e, Yibo Wang, ... **n Chen in Marine Biotechnology
    Article 22 April 2024
  19. nf-core/circrna: a portable workflow for the quantification, miRNA target prediction and differential expression analysis of circular RNAs

    Background

    Circular RNAs (circRNAs) are a class of covalenty closed non-coding RNAs that have garnered increased attention from the research community...

    Barry Digby, Stephen P. Finn, Pilib Ó Broin in BMC Bioinformatics
    Article Open access 24 January 2023
  20. Recent developments in miRNA based recombinant protein expression in CHO

    It is widely accepted that the growing demand for recombinant therapeutic proteins has led to the expansion of the biopharmaceutical industry and the...

    Masoume Bazaz, Ahmad Adeli, ... Noushin Davoudi in Biotechnology Letters
    Article 04 May 2022
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