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1. Dose–response prediction for in-vitro drug combination datasets: a probabilistic approach

   In this paper we propose PIICM, a probabilistic framework for dose–response prediction in high-throughput drug combination datasets. PIICM utilizes a...

   Leiv Rønneberg, Paul D. W. Kirk, Manuela Zucknick in BMC Bioinformatics

   Article Open access 21 April 2023
   

2. Trinexapac-Ethyl Dose–Response Curve for Eucalyptus Growth and Hormonal Crosstalk Between Leaf and Shoot Apical Bud

   Although recent studies have reported stimulatory effect of trinexapac-ethyl (TE) on eucalyptus growth, there is no consensus regarding the best dose...

   Allan Lopes Bacha, Renata Thaysa da Silva Santos, ... Pedro Luís da Costa Aguiar Alves in Journal of Plant Growth Regulation

   Article 05 July 2024
   

3. Design principles of improving the dose-response alignment in coupled GTPase switches

   “Dose-response alignment” (DoRA), where the downstream response of cellular signaling pathways closely matches the fraction of activated receptor,...

   Lingxia Qiao, Pradipta Ghosh, Padmini Rangamani in npj Systems Biology and Applications

   Article Open access 31 January 2023
   

4. Dose-response relationship of MSCs as living Bio-drugs in HFrEF patients: a systematic review and meta-analysis of RCTs

   Background

   Mesenchymal stem cells (MSCs) have emerged as living biodrugs for myocardial repair and regeneration. Recent randomized controlled trials...

   Ziyad T. Ahmed, Maha Saad Zain Al-Abeden, ... Khawaja Husnain Haider in Stem Cell Research & Therapy

   Article Open access 13 June 2024
   

5. Calcium regulates primary nitrate response associated gene transcription in a time- and dose-dependent manner

   Nitrate (NO ₃ ⁻ ) is the primary source of nitrogen preferred by most arable crops, including wheat. The pioneering experiment on primary nitrate...

   Sandeep B. Adavi, Lekshmy Sathee in Protoplasma

   Article 28 September 2023
   

6. Dose-response of pests to ethanedinitrile dose-response of weed seeds, soil borne pathogens, and plant-parasitic nematodes to ethanedinitrile

   Ethanedinitrile is a chemical soil fumigant with promising efficacy against several key pests including weeds, nematodes, and soil-borne pathogens....

   Swaminathan Thalavaiasundaram, Husein Ajwa, Mary C. Stevens in Australasian Plant Pathology

   Article Open access 25 January 2023
   

7. Dose-response associations of triglyceride to high-density lipoprotein cholesterol ratio and triglyceride–glucose index with arterial stiffness risk

   Background

   The triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and triglyceride-glucose (TyG) index are novel indexes for...

   Wenkai Zhang, Weifeng Huo, ... Yang Zhao in Lipids in Health and Disease

   Article Open access 20 April 2024
   

8. Dose–Response Assessment of Mitomycin C Genotoxic Effect on ApoE Knockout Mice

   Abstract

   Polychromatophilic erythrocytes (PCE) are a suitable target to assess both acute and chronic genotoxic stress in in vivo models. Mitomycin C...

   M. A. Asanov, M. Y. Sinitsky, ... A. V. Ponasenko in Journal of Evolutionary Biochemistry and Physiology

   Article 01 September 2023
   

9. Effects of camelina oil supplementation on lipid profile and glycemic control: a systematic review and dose‒response meta-analysis of randomized clinical trials

   Background

   This systematic review and dose–response meta-analysis of published randomized controlled trials (RCTs) was conducted to determine the...

   Cyrus Jalili, Sepide Talebi, ... Sajjad Moradi in Lipids in Health and Disease

   Article Open access 07 December 2022
   

10. Dose–Response Effect of Saccharomyces cerevisiae UFMG A-905 on the Prevention of Asthma in an Animal Model

    Probiotics should be administered in adequate amounts to confer health benefits. Probiotic dose–response studies are still missing. Saccharomyces...

    Thamires M. S. Milani, Camila M. Sandy, ... Marcos C. Borges in Probiotics and Antimicrobial Proteins

    Article 29 November 2022
    

11. Low-dose ionizing radiation generates a hormetic response to modify lipid metabolism in Chlorella sorokiniana

    Algal biomass is a viable source of chemicals and metabolites for various energy, nutritional, medicinal and agricultural uses. While stresses have...

    Marina Stanić, Mima Jevtović, ... Jon K. Pittman in Communications Biology

    Article Open access 06 July 2024
    

12. The dose-response relationship of serum uric acid with Dyslipidaemia and its components: a cross-sectional study of a Chinese multi-ethnic cohort

    Background

    The association between serum uric acid (SUA) and the components of dyslipidaemia and their dose-response relationships have not been...

    Lian Peng, Leilei Liu, ... Feng Hong in Lipids in Health and Disease

    Article Open access 03 April 2022
    

13. Zinc Supplementation in Individuals with Prediabetes and type 2 Diabetes: a GRADE-Assessed Systematic Review and Dose-Response Meta-analysis

    Zinc supplementation has therapeutic effects on cardiovascular disease (CVD) risk factors, including dyslipidemia, hyperglycemia, and inflammation as...

    Matin Nazari, Mahlagha Nikbaf-Shandiz, ... Matin Ghanavati in Biological Trace Element Research

    Article 23 October 2023
    

14. The Effect of Parenteral Selenium Therapy on Serum Concentration of Inflammatory Mediators: a Systematic Review and Dose-Response Meta-Analysis of Randomized Clinical Trials

    Selenium can protect against inflammation through its incorporation in selenoenzymes; therefore, in this study, we assessed the effect of parenteral...

    Mitra Hariri, Bahareh Amirkalali, ... Ali Gholami in Biological Trace Element Research

    Article 22 August 2023
    

15. Hormetic Response of Low Dose Gamma on Phaseolus Vulgaris L. Under Drought Stress: Proteinogenic Amino Acids Profile

    The hypothesis about the hormetic effect of low-dose gamma applications (0, 10, 20, 30, 40 Gy- ⁶⁰ Co) on common bean ( Phaseolus vulgaris L.) cultivars...

    Kamile Ulukapi, Ayse Gul Nasircilar in Gesunde Pflanzen

    Article 15 November 2022
    

16. Effect of Zinc Supplementation on Lipid Profile and Body Composition in Patients with Type 2 Diabetes Mellitus: A GRADE-Assessed Systematic Review and Dose-Response Meta-analysis

    The aim of this systematic review and meta-analysis of randomized controlled trials (RCTs) is to investigate the overall effects of zinc...

    Mahsa Khajeh, Shirin Hassanizadeh, ... Gholamreza Askari in Biological Trace Element Research

    Article 15 January 2024
    

17. Effect of Chromium Supplementation on Performance, Carcass Characteristics, Blood Biochemistry, and Immune Response of Unstressed Broiler Chickens: a Dose-Response Meta-Analysis

    Studies investigating the effects of Chromium (Cr) supplementation on unstressed broiler chickens have reported an inconsistent association between...

    Ali Hossein Piray, Saheb Foroutanifar in Biological Trace Element Research

    Article 17 January 2021
    

18. The rise and fall of photosynthesis: hormetic dose response in plants

    The recent recognition that low doses of herbicides, human and veterinary antibiotics, metallic elements, micro/nano-plastics, and various other...

    Evgenios Agathokleous in Journal of Forestry Research

    Article Open access 17 November 2020
    

19. Nitrate dose–response of morpho-physiological parameters in wheat seedlings at ambient and elevated CO₂ conditions

    Increasing atmospheric CO ₂ concentration is responsible for alteration in physiological processes in plants. This study aims at understanding nitrate...

    Birendra K. Padhan, Lekshmy Sathee in Plant Physiology Reports

    Article 06 August 2022
    

20. The Effect of Oral Magnesium Supplementation on Inflammatory Biomarkers in Adults: A Comprehensive Systematic Review and Dose–response Meta-analysis of Randomized Clinical Trials

    This is a comprehensive systematic review and dose–response meta-analysis evaluating the effects of oral magnesium supplementation on inflammatory...

    Sepide Talebi, Maryam Miraghajani, ... Hamed Mohammadi in Biological Trace Element Research

    Article 18 June 2021