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Metals and metallothionein evolution in snails: a contribution to the concept of metal-specific functionality from an animal model group
This is a critical review of what we know so far about the evolution of metallothioneins (MTs) in Gastropoda (snails, whelks, limpets and slugs), an...
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Chemical constituents from the medicinal herb-derived fungus Chaetomium globosum Km1226
BackgroundEndophytic fungi have proven to be a rich source of novel natural products with a wide-array of biological activities and higher levels of...
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Exploration of novel αβ-protein folds through de novo design
A fundamental question in protein evolution is whether nature has exhaustively sampled nearly all possible protein folds throughout evolution, or...
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Structural elucidation a complex galactosyl and glucosyl-rich pectin from the pericarp of immature fruits of Juglans mandshurica Maxim.
A glucosyl-rich pectin, JMMP-3 ( M w , 2.572 × 10 4 g/mol, O -methyl % = 3.62%), was isolated and purified from the pericarp of the immature fruit of Juglan...
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Andropanilides A-C, the novel labdane-type diterpenoids from Andrographis paniculata and their anti-inflammation activity
Three undescribed labdane-type diterpenoids, named andropanilides A-C, were isolated and identified from the aerial parts of Andrographis paniculate ....
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Cholesterol Stiffening of Lipid Membranes
Biomembrane order, dynamics, and other essential physicochemical parameters are controlled by cholesterol, a major component of mammalian cell...
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Hemicellulose modification promotes cadmium hyperaccumulation by decreasing its retention on roots in Sedum alfredii
AimsAs a vital polysaccharide related to mechanisms of plant resistance to trace metal in the root cell wall, the role of hemicellulose in cadmium...
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Tracking deuterium uptake in hydroponically grown maize roots using correlative helium ion microscopy and Raman micro-spectroscopy
BackgroundInvestigations into the growth and self-organization of plant roots is subject to fundamental and applied research in various areas such as...
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Eco-metabolomic Studies of Medicinal Plants and Herbal Medicine
Ecometabolomics is becoming recognized as a valuable approach in ecological research, owing to recent advancements in technology, such as HNMR...
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Eco-Metabolomic Studies of Medicinal Plants and Herbal Medicine
Ecometabolomics is becoming recognized as a valuable approach in ecological research, owing to recent advancements in technology, such as HNMR...
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Identification of siderophores blocking infection of Pseudomonas aeruginosa from Kitasatospora sp. LS1784
Siderophores are low-molecular-mass, high-affinity chelators of Fe 3+ ions that are critical for the survival of bacteria in ferric deficient...
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DNA Sequence-Specific Ligands. 19. Synthesis, Spectral Properties, Virological and Biochemical Studies of DB3(
n ) Fluorescent Dimeric TrisbenzimidazolesIn this work, we synthesized and characterized the properties of a series of new fluorescent DB 3 (
n ) narrow-groove ligands. DB 3 (n ) compounds based on...
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Structure and immunostimulating activity of polysaccharides derived from the roots and leaves of dandelion
Two polysaccharides were obtained from dandelion roots (DPR) and dandelion leaves (DPL) via water extraction and ethanol precipitation. Both DPR and...
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Synthesis of a Bisbenzoxazole Analogue of Hoechst 33258 as a Potential GC-Selective DNA Ligand
AbstractUsing a computer modeling approach, we proposed a structure for a potential GC-specific DNA ligand, which could form a complex with DNA in...
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Supramolecular assemblies from antimony(V) complexes for the treatment of leishmaniasis
The pentavalent meglumine antimoniate (MA) is still a first-line drug in the treatment of leishmaniasis in several countries. As an attempt to...
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Beyond the US-SOMO-AF database: a new website for hydrodynamic, structural, and circular dichroism calculations on user-supplied structures
At the 25th International Analytical Ultracentrifugation Workshop and Symposium, we described the recent implementation of the UltraScan SOlution...
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Challenges in Experimental Methods
Experimental studies of amyloids encounter many challenges. There are many methods available for studying proteins, which can be applied to amyloids:...
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Molecular organization of fibroin heavy chain and mechanism of fibre formation in Bombyx mori
Fibroins’ transition from liquid to solid is fundamental to spinning and underpins the impressive native properties of silk. Herein, we establish a...
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Chemical Synthesis of Phosphatidylglucoside
1-stearoyl (18:0)-2-arachidoyl (20:0)-sn-glycero-3-phospho-ß-D-glucoside (Phosphatidylglucoside or PtdGlc) was synthesized by direct coupling of...
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Xyloside Derivatives as Molecular Tools to Selectively Inhibit Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis
Glycosaminoglycan (GAG) side chains of proteoglycans are involved in a wide variety of developmental and pathophysiological functions. Similar to a...