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In-Silico Analysis of the High-Risk Missense Variants in PTH1R Gene and Association with Primary Failure of Tooth Eruption (PFE)
Primary eruption failure (PFE) is a rare condition characterized by the cessation of tooth eruption posteriorly. Due to a mutation in the PTH1R gene,...
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Genetic variability analysis of Russian cultivars of ryegrass (Lolium) based on SCoT markers
BackgroundRyegrass is a promising crop for the development of meadow farming in the world. More than 1000 cultivated varieties widely used in feed...
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In silico molecular and morphological analysis of rice blast resistant gene Pi-ta in Sri Lankan rice germplasm
BackgroundPi-ta is a major blast resistant gene, introgressed from indica rice varieties. In this study, diversity of the Pi-ta gene of 47 Sri...
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ApoB gene polymorphism (rs676210) and its pharmacogenetics impact on atorvastatin response among Iraqi population with coronary artery disease
BackgroundDrug response is below genetic influence, proven by the genetic variants. Pharmacogenetics trials are performed in many diseases, including...
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Optimization of High Resolution Melting (HRM) Method for Genoty** and Estimating the Frequency of SNP rs751402 on ERCC5 Gene in Vietnamese Breast Cancer Patients
Breast cancer (BC) is the leading cancer-causing death for women worldwide. Among BC-causing genes, ERCC5 plays an important role in DNA damage...
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Analysis of selected polymorphisms in FOXP3 gene in a cohort of Egyptian patients with schizophrenia
BackgroundSchizophrenia is a chronic mental disorder with different symptoms. The environmental and genetic factors are suggested to be the etiology...
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Heparanase (HPSE) gene polymorphism (rs12503843) contributes as a risk factor for hepatocellular carcinoma (HCC): a pilot study among Egyptian patients
BackgroundHeparanase activity was found to be included in human cancer development and growth. Heparanase ( HPSE ) gene single nucleotide...
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Computational Intelligence Methods for Predicting Cancer Susceptibility from SNP Data
Cancer is a chronic disease where cells inside the body grow abnormally. It is a complicated disease with various molecular changes brought on by...
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Lack of Association of CYP2C9:c.430C>T and SCN1A:c.3184A>G Polymorphisms with Epilepsy Risk or Drug Resistance in Childhood Epilepsy Syndromes in Lagos State, Nigeria
Pharmacoresistance has been a constant challenge in managing children with childhood epilepsy syndromes, and this has been attributable in part to...
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Optimization of HRM Method for Genoty** and Estimating the Frequency of SNP rs12325489 on Lincrna Gene in Vietnamese Breast Cancer Patients
Breast cancer (BC) is the most dangerous cancer in women worldwide. Among well—known BC penetrant genes, LincRNA plays an important role in the...
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Comparison of KNN and SVM Methods for the Accuracy of Individual Race Classification Prediction Based on SNP Genetic Data
A single nucleotide polymorphism (SNP) is a DNA sequence variation in a population. SNP is just a single nucleotide difference in the genome. Many...
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De novo assembly and comparative genome analysis for polyhydroxyalkanoates-producing Bacillus sp. BNPI-92 strain
BackgroundCertain Bacillus species play a vital role in polyhydroxyalkanoate (PHA) production. However, most of these isolates did not properly...
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Single to three nucleotide polymorphisms assay of miRNA-21 using DNA capped gold nanoparticle-electrostatic force microscopy system
Aberrant expression of microRNA (miRNA) in biological cells is crucial evidence for early diagnosis of cancer. Improvements in molecular detection...
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Prognostic Value of PFKM Polymorphisms and Susceptibility to Epithelial Ovarian Cancer in Han Women of Southwest China
Phosphofructokinase muscle (PFKM), encoded by PFKM on chromosome 12q13.11, is abundantly expressed in skeletal muscle. PFKM is a member of the...
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Design and characterization of a SYBR Green I-based melting curve method for investigation of HER2I655V polymorphism in breast cancer
BackgroundBreast cancer is a disease in which cell grows rapidly forming a mass in the breast. HER2 polymorphisms Ile655Val have been studied as...
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Suitability of target region amplified polymorphism (TRAP) markers to discern genetic variability in sweet sorghum
BackgroundSweet sorghum is an emerging biofuel candidate crop with multiple benefits as a source of biomass energy. Increase of biomass and sugar...
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Implementation of Exome Sequencing to Identify Rare Genetic Diseases
Modern high-throughput genomic testing using next-generation sequencing (NGS) has led to a significant increase in the successful diagnosis of rare...
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Genetic diversity, variation, and structure of two populations of bigfin reef squid (Sepioteuthis lessoniana d’Orbigny) in Con Dao and Phu Quoc islands, Vietnam
BackgroundBigfin squid is one of the economically important seafood resources in Vietnam’s fisheries and the waters around Con Dao and Phu Quoc...
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Genetic Polymorphism β-Lactoglobulin Gene in Dubska Pramenka Sheep Breed
Polymorphism exists in β-lactoglobulin (LGB) milk encoding gene in dairy animals, resulting in presence of different protein isoforms in milk. There...
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Determination of Genetic Diversity with ISSR Assay Among Barley Genotypes
Molecular markers are widely used to study genetic diversity and associations between genotypes. To extend the genetic base of the barley germplasm,...
