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Assembling Au8 clusters on surfaces of bifunctional nanoimmunomodulators for synergistically enhanced low dose radiotherapy of metastatic tumor
BackgroundRadiotherapy is one of the mainstays of cancer therapy and has been used for treating 65–75% of patients with solid tumors. However,...
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Light-triggered multifunctional nanoplatform for efficient cancer photo-immunotherapy
Cancer immunotherapy is limited by the immune escape of tumor cells and adverse effects. Photo-immunotherapy, the combination of immunotherapy and...
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Enhancement of antitumor immunotherapy using mitochondria-targeted cancer cell membrane-biomimetic MOF-mediated sonodynamic therapy and checkpoint blockade immunotherapy
Immunotherapeutic interventions represent a promising approach to treating cancer, with strategies such as immune checkpoint blockade (ICB),...
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Cancer cell membrane-coated nanoparticles for bimodal imaging-guided photothermal therapy and docetaxel-enhanced immunotherapy against cancer
BackgroundMono-therapeutic modality has limitations in combating metastatic lesions with complications. Although emerging immunotherapy exhibits...
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Functional nanovesicles displaying anti-PD-L1 antibodies for programmed photoimmunotherapy
BackgroundPhotoimmunotherapy is one of the most promising strategies in tumor immunotherapies, but targeted delivery of photosensitizers and...
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Radiotherapy combined with nano-biomaterials for cancer radio-immunotherapy
Radiotherapy (RT) plays an important role in tumor therapy due to its noninvasiveness and wide adaptation. In recent years, radiation therapy has...
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Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity
SLC15A4 is an endolysosome-resident transporter linked with autoinflammation and autoimmunity. Specifically, SLC15A4 is critical for Toll-like...
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The quest for nanoparticle-powered vaccines in cancer immunotherapy
Despite recent advancements in cancer treatment, this disease still poses a serious threat to public health. Vaccines play an important role in...
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Methods to Activate the NLRP3 Inflammasome
The inflammasome-nucleating cytoplasmic sensor protein NLRP3 (NACHT-, LRR, and PYD domains-containing protein 3, also known as NOD-like receptor...
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Therapeutic and Diagnostic Uses of Magnetic Nanoparticles in Cancer
Magnetic nanoparticle (MNP)-based technologies are now often used in biological systems for therapeutic or diagnostic applications. Recent...
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Nanovaccine-based strategies for lymph node targeted delivery and imaging in tumor immunotherapy
Therapeutic tumor vaccines have attracted considerable attention in the past decade; they can induce tumor regression, eradicate minimal residual...
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Roles of MXenes in biomedical applications: recent developments and prospects
....With the development of nanomedical technology, the application of various novel nanomaterials in the biomedical field has been greatly developed...
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Nanomaterials: small particles show huge possibilities for cancer immunotherapy
With the economy's globalization and the population's aging, cancer has become the leading cause of death in most countries. While imposing a...
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Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate
BackgroundCitric acid is typically produced industrially by Aspergillus niger -mediated fermentation of a sucrose-based feedstock, such as molasses....
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Engineered extracellular vesicles-like biomimetic nanoparticles as an emerging platform for targeted cancer therapy
Nanotechnology offers the possibility of revolutionizing cancer theranostics in the new era of precision oncology. Extracellular vesicles (EVs)-like...
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Combination of polylactide with cellulose for biomedical applications: a recent overview
This review summarizes the use of cellulose and polylactide for medical applications with particular emphasis on modern dressings. Although classic...
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Recent developments in mesoporous polydopamine-derived nanoplatforms for cancer theranostics
Polydopamine (PDA), which is derived from marine mussels, has excellent potential in early diagnosis of diseases and targeted drug delivery owing to...
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Engineered extracellular vesicles: potentials in cancer combination therapy
Extracellular vesicles (EVs) are a group of secretory vesicles with cell-derived membrane and contents. Due to the cargo delivery capability, EVs can...
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Nano-immunotherapy: overcoming delivery challenge of immune checkpoint therapy
Immune checkpoint (ICP) molecules expressed on tumor cells can suppress immune responses against tumors. ICP therapy promotes anti-tumor immune...
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Injectable Hydrogels for Intratumoral Administration Against Breast Cancer
Breast cancer poses a significant health risk and remains the most prevalent cancer among women. The side effects associated with traditional...
