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Sensitive and Portable Detection of Bacteria Using Exonuclease-III (Exo-III) Assisted Signal Amplification and Personal Glucose Meters
Despite major advances in combating pathogenic bacteria caused infection, infectious diseases remain a major cause of death today. A variety of...
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Exonuclease III-propelled DNAzyme walker: an electrochemical strategy for microRNA diagnostics
MicroRNA detection is crucial for early infectious disease diagnosis and rapid cancer screening. However, conventional techniques like reverse...
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Exonuclease III assisted exponential amplification reaction (EXPAR) for specific miRNA-155 analysis during post-anesthetic nursing
The persistent obstacle in precise and sensitive identification of microRNAs (miRNAs) pertains to the advancement of expeditious and effective...
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Direct and accurate miRNA detection based on CRISPR/Cas13a-triggered exonuclease-iii-assisted colorimetric assay
The abnormally expressed microRNAs (miRNAs) serve as crucial indicators for disease diagnosis and are strongly associated with the progression of...
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An Exo III-powered closed-loop DNA circuit architecture for biosensing/imaging
With their regulated Boolean logic operations in vitro and in vivo, DNA logic circuits have shown great promise for target recognition and disease...
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Self-assembled Nanosheets of Perylene Monoamide Derivative as Sensitive Fluorescent Biosensor for Exonuclease III Activity
Enzymes containing 3′ → 5′ exonuclease activities play an important role in various key cellular and physiological processes. The development of...
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A highly sensitive fluorescence biosensor for aflatoxins B1 detection based on polydiacetylene liposomes combined with exonuclease III-assisted recycling amplification
A fluorescence biosensor for determination of aflatoxin B 1 (AFB 1 ) based on polydiacetylene (PDA) liposomes and exonuclease III (EXO III)-assisted...
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Exonuclease-III Assisted the Target Recycling Coupling with Hybridization Chain Reaction for Sensitive mecA Gene Analysis by Using PGM
In the field of neonatal infections nursing, methicillin-resistant Staphylococcus aureus (MRSA) is a major bacterial pathogen. Here, we present a...
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Exo-III Enzyme–Assisted Triple Cycle Signal Amplifications for Sensitive and Accurate Identification of Pathogenic Bacteria
Early determination of infectious pathogens is vitally important to select appropriate antibiotics, and to manage nosocomial infection. Herein, we...
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Target-mediated competitive hybridization of hairpin probes for kanamycin detection based on exonuclease III cleavage and DNAzyme catalysis
Based on aptamer recognition and target-mediated competitive hybridization of hairpin probes, we developed a fluorescence sensor for kanamycin (KAN)...
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A Graphene Oxide-based Assay for Sensitive Osteonecrosis of the Femoral Head (ONFH) related microRNA Detection via Exonuclease-III Assisted Dual Signal Cycle
Accurate detection of circulating microRNAs (miRNAs) plays a vital role in the diagnosis of various diseases. The current miRNA detection methods,...
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A low-noise ratiometric fluorescence biosensor for detection of Pb2+ based on DNAzyme and exonuclease III–assisted cascade signal amplification
As a common heavy metal ion with strong toxicity and wide distribution, lead ions (Pb 2+ ) had great harm to the human body. In this work, a low-noise...
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Graphene-based fluorometric determination of agrD gene transcription in methicillin-resistant Staphylococcus aureus using exonuclease III-aided target recycling and DNA walker cascade amplification
A graphene-based bioassay is described for the fluorometric determination of agrD gene transcription (mRNA) in methicillin-resistant Staphylococcus...
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Homogeneous photoelectrochemical biosensor for microRNA based on target-responsive hydrogel coupled with exonuclease III and nicking endonuclease Nb.BbvCI assistant cascaded amplification strategy
MicroRNAs can serve as biomarkers for many cancers, so it is significant to develop simple and sensitive strategies for microRNAs detection....
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A label-free electrochemical magnetic aptasensor based on exonuclease III–assisted signal amplification for determination of carcinoembryonic antigen
A novel label-free and exonuclease III (Exo III)–assisted signal amplification electrochemical aptasensor was constructed for the determination of...
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Ultrasensitive and colorimetric small extracellular vesicles (sEVs) analysis via dual-cycle signal tool
For the clinical diagnosis of diseases and for basic biological research, it is crucial to develop a trustworthy and efficient method for detecting...
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A fluorometric aptamer-based assay for ochratoxin A by using exonuclease III-assisted recycling amplification
A fluorometric assay is described for ochratoxin A (OTA) using an aptamer. The method is based on exonuclease-assisted recycling amplification. The...
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In situ generated CdTe quantum dot-encapsulated hafnium polymer membrane to boost electrochemiluminescence analysis of tumor biomarkers
Exploring the construction of an interface with bright emission, fabulous stability, and good function to develop high-performance...
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A gold nanoparticle-based colorimetric mercury(II) biosensor using a DNA probe with phosphorothioate RNA modification and exonuclease III-assisted signal amplification
Herein, we report a rapid and sensitive colorimetric detection of Hg 2+ by designing a specific DNA probe with phosphorothioate RNA modification...
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A novel DNA detection using spherical identification probe and strand displacement reaction-initiated silver nanocluster switch
Herein, we developed a novel fluorescent assay using spherical identification probes and toehold-mediated strand displacement reaction-initiated...