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Coumarins as Emerging Anti-Viral Compounds from Natural Origins: Ethnopharmacology, Chemistry, Mechanism of Action, Clinical and Preclinical Studies, and Future Perspectives
From the natural origin, more than 1300 coumarins have already been recognized. Coumarins are natural products and secondary metabolites in plants,...
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Electrochemical biosensor based on antibody-modified Au nanoparticles for rapid and sensitive analysis of influenza A virus
To cope with the easy transmissibility of the avian influenza A virus subtype H1N1, a biosensor was developed for rapid and highly sensitive...
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Lysosomal escaped protein nanocarriers for nuclear-targeted siRNA delivery
In the process of drug carrier design, lysosome degradation in cells is often neglected, which makes a considerable number of drugs not play a role....
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Nanostructures for prevention, diagnosis, and treatment of viral respiratory infections: from influenza virus to SARS-CoV-2 variants
Viruses are a major cause of mortality and socio-economic downfall despite the plethora of biopharmaceuticals designed for their eradication....
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Plants Showing Antiviral Activity with Emphasis on Secondary Metabolites and Biological Screening
Plants have been used for centuries in traditional medicine systems for their therapeutic properties. In recent years, there has been growing...
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Camphecene and ginsamide: dynamics of potential interactions with the influenza virus M2 channel
The structure of the full-size M2 channel of influenza virus generated using neural networks and homology modeling was considered. The binding...
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Voltammetric Determination of Measles Virus Antibodies Using a Glassy Carbon Electrode Modified with 2-Propargyltio-6-nitro-7-hydroxy-4H-1,2,4-triazolo-4,7-dihydro[5,1-c]-1,2,4-triazine
AbstractA method is proposed for the voltammetric determination of measles antibodies using a glassy carbon electrode modified with...
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Tobacco-Based Vaccines, Hopes, and Concerns: A Systematic Review
Emerging infectious diseases have vigorously devastated the global economy and health sector; cost-effective plant-based vaccines (PBV) can be the...
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Photoinduced Hydrophilicity and Antimicrobial Activity by Photocatalysis
Biodegradable plastics that are decomposed by microorganisms are attracting attention as marine pollution caused by microplastics becomes more...
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Reverse Genetics and Its Usage in the Development of Vaccine Against Poultry Diseases
Vaccines are the most effective and economic way of combating poultry viruses. However, the use of traditional live-attenuated poultry vaccines has...
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An aggregation-induced emission fluorogen/DNA probe carrying an endosome esca** pass for tracking reduced thiol compounds in cells
The fluorescent nanoprobes for reduced thiol compounds (represented by glutathione, GSH) are constructed based on the aggregation-induced emission...
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Coumarins as Emerging Antiviral Compounds from Natural Origins: Ethnopharmacology, Chemistry, Mechanism of Action, Clinical, Preclinical Studies, and Future Perspectives
From the natural origin, more than 1300 coumarins have already been recognized. Coumarins are natural products and secondary metabolites in plants,...
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Neuraminidase Inhibitory Activities of Some Alcoholic Plant Extracts and Chemical Compounds
AbstractIn today’s world, disease rates are increasing day after day because of environmental factors, lifestyles and technology. Although there are...
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Lectin-Like Activity of Hemocyanin in Freshwater Prawn, Macrobrachium rosenbergii
Lectins are proteins that bind to the carbohydrate moieties on surface of bacteria, erythrocytes and other cells of invertebrates causing...
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Anti-Viral Potential of Curcumins: Ethnopharmacology, Chemistry, and Clinical Studies Focusing on Mechanism of Action and Future Perspectives
Viruses have always been a serious public health concern, and scientists have worked diligently to make new anti-viral medicines. Virus infections...
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Extraction of the outer membrane protein pertactin from Bordetella pertussis with urea for the production of acellular pertussis vaccine
Pertactin (PRN), a non-fimbrial outer membrane protein of Bordetella pertussis , is the limiting component of the acellular pertussis vaccine because...
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Global Health and Viral Diseases: Past, Present, and Future
Viral diseases are one of the most common and rapidly contagious ways to impair one’s health. Hence, finding new ways to combat the spread and treat...
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Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
Nonsense mutations generating premature termination codons (PTCs) in various genes are frequently associated with somatic cancer and hereditary human...
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DNA Vaccines in Pigs: From Immunization to Antigen Identification
DNA vaccinationVaccination is one of the most fascinating vaccine strategies currently in development. Two of the main advantages of DNA...
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Management of Antinutrients in Forages
Fulfilling the nutritional requirements of neonatal, growing and breeding livestock is important for a successful livestock operation. The...