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Inhalation Therapy in Pulmonary Tuberculosis
Tuberculosis (TB) is a historical disease that can trace its impact on humanityHumanity back in time thousands of years. A bacterial... -
Inhalation Lenalidomide-Loaded Liposome for Bleomycin-Induced Pulmonary Fibrosis Improvement
Idiopathic pulmonary fibrosis (IPF) is a progressive, fibrotic interstitial lung disease with unclear etiology and increasing prevalence. Pulmonary...
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Recent developments in dry powder inhalation (DPI) formulations for lung-targeted drug delivery
BackgroundDry powder inhalation (DPI) formulations have been widely studied for the treatment of respiratory diseases, including COVID-19, which have...
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Safety of Intravenous and Inhalation Anesthetics
Here is presented, in chronological order, the studies that established the standards and determined the parameters currently considered for the safe... -
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Toxicological inhalation studies in rats to substantiate grou** of zinc oxide nanoforms
BackgroundSignificant variations exist in the forms of ZnO, making it impossible to test all forms in in vivo inhalation studies. Hence, grou** and...
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Myrtenol Inhalation Mitigates Asthma-Induced Cognitive Impairments: an Electrophysiological, Behavioral, Histological, and Molecular Study
Asthma is an inflammatory disorder with significant health problems. It generally affects the lungs but can also impact brain performance via several...
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Antimicrobial Peptides and Proteins for Inhalation
Antimicrobial peptides and proteins (APPs) are gaining attraction as powerful agents against multidrug-resistant bacteria. The inhalation delivery of... -
Positive Neuroprotective Effect of Argon Inhalation after Photochemically Induced Ischemic Stroke Model in Rats
We studied the effect of 2-h inhalation of argon-oxygen mixture (Ar 70%/O 2 30%) after photochemically induced stroke and on days 2 and 3 after stroke...
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Effect of Xe/O2 Inhalation on Hemostasis in Experimental Thromboplastin Pneumonitis
We studied the effectiveness of Xe/O 2 mixture inhalation (30% Xe and 70% O 2 , 20 min for 5 days) in a model of experimental thromboplastin...
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Effect of Nasal Inhalation on Drug Particle Deposition and Size Distribution in the Upper Airway: With Soft Mist Inhalers
Delivery of drugs to the lungs is commonly achieved using nasal and/or oral breathing-assisted techniques. The route of inhalation can substantially...
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Toxicokinetics of silver element following inhalation of silver nitrate in rats
Silver (Ag) and its compounds are priority contaminants, for which toxicological effects are well documented, but their toxicokinetics are not fully...
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Spray Freeze Drying of Biologics: A Review and Applications for Inhalation Delivery
Biopharmaceuticals have established an indisputable presence in the pharmaceutical pipeline, enabling highly specific new therapies. However,...
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Adult consequences of repeated nicotine and Δ9-tetrahydrocannabinol (THC) vapor inhalation in adolescent rats
RationaleUse of electronic drug delivery systems (EDDS, “e-cigarettes”) to ingest nicotine and Δ 9 -tetrahydrocannabinol (THC) has surged in...
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Effects of chronic vapor inhalation on mouse body weight, lung morphology, and inflammatory cytokines using a low vapor exposure design
Electronic-cigarette (ECIG) use increased over the last decade as many find va** as a safe alternative to cigarettes; however, the safety of ECIGs...
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Advancements in Particle Engineering for Inhalation Delivery of Small Molecules and Biotherapeutics
Dry powder inhalation formulations have become increasingly popular for local and systemic delivery of small molecules and biotherapeutics. Powder...
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Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats
BackgroundExposure to micro- and nanoplastic particles (MNPs) in humans is being identified in both the indoor and outdoor environment. Detection of...