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Chronic Valvular Heart Disease
Valvular heart disease (VHD) refers to a series of disorders that affect the heart valves by altering their correct functioning; they are divided...
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Trans-aortic Valvular Ejection Fraction for Monitoring Recovery of Patients with Ventricular Systolic Heart Failure
Durable mechanical circulatory support in the form of left ventricular (LV) assist device (LVAD) therapy is increasingly considered in the context of...
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Heart Valve Regeneration
The valves of the heart cannot regenerate spontaneously. Therefore, heart valve disease generally necessitates surgical repair or replacement of the...
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Anti-IL-17 Inhibits PINK1/Parkin Autophagy and M1 Macrophage Polarization in Rheumatic Heart Disease
Rheumatic heart disease (RHD) is an important and preventable cause of cardiovascular death and disability, but the lack of clarity about its exact...
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Is breathing frequency a potential means for monitoring exercise intensity in people with atrial fibrillation and coronary heart disease when heart rate is mitigated?
PurposeModerate-intensity aerobic exercise is safe and beneficial in atrial fibrillation (AF) and coronary heart disease (CHD). Irregular or rapid...
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The aetiology and incidence of infective endocarditis in people living with rheumatic heart disease in tropical Australia
PurposeTo define the incidence and microbiological aetiology of infective endocarditis (IE) in patients with rheumatic heart disease (RHD) in...
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Toward a diagnostic CART model for Ischemic heart disease and idiopathic dilated cardiomyopathy based on heart rate total variability
Diagnosis of etiology in early-stage ischemic heart disease (IHD) and dilated cardiomyopathy (DCM) patients may be challenging. We aimed at...
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Multiscale Finite Element Modeling of Left Ventricular Growth in Simulations of Valve Disease
Multiscale models of the cardiovascular system are emerging as effective tools for investigating the mechanisms that drive ventricular growth and...
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Design of ear-contactless stethoscope and improvement in the performance of deep learning based on CNN to classify the heart sound
Cardiac-related disorders are rapidly growing throughout the world. Accurate classification of cardiovascular diseases is an important research topic...
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Genome Editing and Heart Failure
Heart failure is a leading and growing cause of morbidity and mortality worldwide and clinically is defined by the presence of typical symptoms and...
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Outcome of carcinoid heart syndrome in patients enrolled in the SwissNet cohort
BackgroundCarcinoid heart disease is a rare disease which develops in patients with functional neuroendocrine tumors in an advanced tumor state....
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Patient-specific finite element analysis of heart failure and the impact of surgical intervention in pulmonary hypertension secondary to mitral valve disease
Pulmonary hypertension (PH), a chronic and complex medical condition affecting 1% of the global population, requires clinical evaluation of right...
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Survival of cancer patients with pre-existing heart disease
BackgroundWhile cancer outcomes have improved over time, in Northern Ireland they continue to lag behind those of many other developed economies. The...
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Palliative Care for People Living with Heart Failure
Heart failure (HF) is a clinical syndrome affecting approximately 5 million people worldwide, causing a significant symptom burden and reducing both...
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In Vivo Three-Dimensional Geometric Reconstruction of the Mouse Aortic Heart Valve
Aortic valve (AV) disease is a common valvular lesion in the United States, present in about 5% of the population at age 65 with increasing...
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Role of Renin Angiotensin System in the Pathophysiology of Coronary Heart Disease: Advancements in Diagnosis, Therapy and Preventive Strategies
The incidence of coronary heart diseaseCoronary heart disease (CHD) has been escalating over the years, and epidemiological data suggests that CHD...
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Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model
We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two...
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Expression of Circulating Rennin—Angiotensin—Aldosterone-Related microRNAs in Patients with Thyrotoxic Heart Disease
Thyrotoxic heart disease (THD) is a common and severe complication of hyperthyroidism and the etiology of this complication remains poorly...