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Showing 1-20 of 2,883 results
  1. Transposable Element Structural Variants in Parkinson’s Disease: Focusing on Genoty** Alu Transposable Element Insertions with TypeTE

    Genetic variation contributes significantly to Parkinson’s disease (PD)Parkinson’s disease (PD) risk, onset, and progression. However, most of the...
    Kimberley Billingsley, Jainy Thomas, Clément Goubert in Genomic Structural Variants in Nervous System Disorders
    Protocol 2022
  2. Identification of transposable element families from pangenome polymorphisms

    Background

    Transposable Elements (TEs) are segments of DNA, typically a few hundred base pairs up to several tens of thousands bases long, that have...

    Pío Sierra, Richard Durbin in Mobile DNA
    Article Open access 26 June 2024
  3. Transposable element evolution in mammals

    Chiara Anania in Nature Genetics
    Article 12 June 2023
  4. Transposable elements: McClintock’s legacy revisited

    In 1983, Barbara McClintock was awarded the Nobel Prize in Physiology or Medicine for her discovery of transposable elements. This discovery was...

    Cédric Feschotte in Nature Reviews Genetics
    Article 18 September 2023
  5. Recurrent co-domestication of PIF/Harbinger transposable element proteins in insects

    Background

    Transposable elements (TEs) are selfish DNA sequences capable of moving and amplifying at the expense of host cells. Despite this, an...

    Dragomira N. Markova, Fatema B. Ruma, ... Esther Betrán in Mobile DNA
    Article Open access 30 November 2022
  6. Distribution of Small RNAs Along Transposable Elements in Vitis vinifera During Somatic Embryogenesis

    Metaviridae is a family of reverse-transcribing viruses, closely related to retroviruses; they exist within their host’s DNA as transposable...
    Silvia Rotunno, Paola Leonetti, ... Vitantonio Pantaleo in Viral Metagenomics
    Protocol 2024
  7. Towards targeting transposable elements for cancer therapy

    Transposable elements (TEs) represent almost half of the human genome. Historically deemed ‘junk DNA’, recent technological advancements have...

    Yonghao Liang, Xuan Qu, ... Ting Wang in Nature Reviews Cancer
    Article 16 January 2024
  8. The Role of Transposable Elements in Long-Term Memory Formation

    Abstract

    A number of experimental studies are described that challenge the significance of synaptic plasticity and prove the role of transposable...

    R. N. Mustafin, E. K. Khusnutdinova in Russian Journal of Genetics
    Article 01 April 2024
  9. Transposable elements in mammalian chromatin organization

    Transposable elements (TEs) are mobile DNA elements that comprise almost 50% of mammalian genomic sequence. TEs are capable of making additional...

    Heather A. Lawson, Yonghao Liang, Ting Wang in Nature Reviews Genetics
    Article 07 June 2023
  10. Transposable Elements: Emerging Therapeutic Targets in Neurodegenerative Diseases

    Neurodegenerative diseases, such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and amyotrophic lateral sclerosis (ALS), are characterized by...

    Shrishti Singh, Maheshkumar R. Borkar, Lokesh Kumar Bhatt in Neurotoxicity Research
    Article 25 January 2024
  11. Meeting report: transposable elements at the crossroads of evolution, health and disease 2023

    The conference “Transposable Elements at the Crossroads of Evolution, Health and Disease” was hosted by Keystone Symposia in Whistler, British...

    Irina R. Arkhipova, Kathleen H. Burns, ... Henry L. Levin in Mobile DNA
    Article Open access 27 November 2023
  12. Migrators within migrators: exploring transposable element dynamics in the monarch butterfly, Danaus plexippus

    Background

    Lepidoptera (butterflies and moths) are an important model system in ecology and evolution. A high-quality chromosomal genome assembly is...

    Tobias Baril, Alexander Hayward in Mobile DNA
    Article Open access 16 February 2022
  13. Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells

    Transposable elements (TEs) are parasitic DNA sequences accounting for over half of the human genome. Tight control of the repression and activation...

    Tongyu Sun, Yueyuan Xu, ... Yarui Diao in Nature Genetics
    Article 20 July 2023
  14. Reproducible evaluation of transposable element detectors with McClintock 2 guides accurate inference of Ty insertion patterns in yeast

    Background

    Many computational methods have been developed to detect non-reference transposable element (TE) insertions using short-read whole genome...

    **gxuan Chen, Preston J. Basting, ... Casey M. Bergman in Mobile DNA
    Article Open access 14 July 2023
  15. Transposable elements as essential elements in the control of gene expression

    Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile elements, make up a significant portion of the genomes of...

    Alemu Gebrie in Mobile DNA
    Article Open access 18 August 2023
  16. Orthoptera-TElib: a library of Orthoptera transposable elements for TE annotation

    Transposable elements (TEs) are a major component of eukaryotic genomes and are present in almost all eukaryotic organisms. TEs are highly dynamic...

    Xuanzeng Liu, Lina Zhao, ... Yuan Huang in Mobile DNA
    Article Open access 15 March 2024
  17. CRISPR-TE: a web-based tool to generate single guide RNAs targeting transposable elements

    Background

    The CRISPR/Cas systems have emerged as powerful tools in genome engineering. Recent studies highlighting the crucial role of transposable...

    Yixin Guo, Ziwei Xue, ... Wanlu Liu in Mobile DNA
    Article Open access 01 February 2024
  18. A pangenome-guided manually curated library of transposable elements for Zymoseptoria tritici

    Objectives

    High-quality species-specific transposable element (TE) libraries are required for studies to elucidate the evolutionary dynamics of TEs...

    Tobias Baril, Daniel Croll in BMC Research Notes
    Article Open access 16 November 2023
  19. The Dfam community resource of transposable element families, sequence models, and genome annotations

    Dfam is an open access database of repetitive DNA families, sequence models, and genome annotations. The 3.0–3.3 releases of Dfam ( https://dfam.org ...

    Jessica Storer, Robert Hubley, ... Arian F. Smit in Mobile DNA
    Article Open access 12 January 2021
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