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Metagenomic next-generation sequencing contributes to the diagnosis of mixed pulmonary infection: a case report
BackgroundPulmonary cryptococcosis (PC) and mixed pulmonary infection are difficult to be diagnosed due to the non-specificity and their overlap**...
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Activating A1 adenosine receptor signaling boosts early pulmonary neutrophil recruitment in aged mice in response to Streptococcus pneumoniae infection
BackgroundStreptococcus pneumoniae (pneumococcus) is a leading cause of pneumonia in older adults. Successful control of pneumococci requires robust...
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Metagenomic next-generation sequencing for rapid detection of pulmonary infection in patients with acquired immunodeficiency syndrome
BackgroundAcquired immunodeficiency syndrome (AIDS) is associated with a high rate of pulmonary infections (bacteria, fungi, and viruses). To...
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Virus infection induced pulmonary fibrosis
Pulmonary fibrosis is the end stage of a broad range of heterogeneous interstitial lung diseases and more than 200 factors contribute to it. In...
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Vein wall thickness and severity of pulmonary involvement due to sars n-cov2 virus infection
BackgroundAn observational study involving patients recovered from COVID-19 was conducted in order to evaluate the presence/absence of vein wall...
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Inefficient antiviral response in reconstituted small-airway epithelium from chronic obstructive pulmonary disease patients following human parainfluenza virus type 3 infection
Chronic obstructive pulmonary disease (COPD) affects over 250 million individuals globally and stands as the third leading cause of mortality....
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Epidemiological and clinical characteristics of psittacosis among cases with complicated or atypical pulmonary infection using metagenomic next-generation sequencing: a multi-center observational study in China
BackgroundChlamydia psittaci ( C. psittaci ) causes parrot fever in humans. Development of metagenomic next-generation sequencing (mNGS) enables the...
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Pulmonary Vascular Diseases
Pulmonary vascular diseases or pulmonary vasculopathies represent diseases of pulmonary vasculature that are associated with altered pulmonary...
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Inhalable Nanomedicines for the Treatment of Pulmonary Aspergillosis
Pulmonary aspergillosis is a serious pulmonary fungal infection and a major cause of morbidity and mortality in immunocompromised patients. The...
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Infectious Pulmonary Diseases
Different infectious pathogens like viruses, bacteria, and in rare occasion fungi infect the human respiratory tract leading to the onset of upper...
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A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection
It has been reported that IL-33 receptor ST2 deficiency mitigates Cryptococcus neoformans ( C. neoformans ) pulmonary infection in BALB/c mice. IL-33...
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Pulmonary Drug Delivery
This chapter provides an introductory overview on concepts related to drug delivery to the lungs. Physiological barriers to lung delivery are...
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Successful treatment of sino-pulmonary infection & skull base osteomyelitis caused by New Delhi metallo-β-lactamase-producing Pseudomonas aeruginosa in a renal transplant recipient by using an investigational antibiotic cefepime/zidebactam (WCK 5222)
A case of sino-pulmonary infection with skull base osteomyelitis due to XDR- Pseudomonas aeruginosa in renal transplant recipient was successfully...
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Inhalation Therapy in Pulmonary Tuberculosis
Tuberculosis (TB) is a historical disease that can trace its impact on humanityHumanity back in time thousands of years. A bacterial...
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Pulmonary Infection Caused by Strongyloides stercoralis
PurposeStrongyloidiasis is mainly prevalent in develo** countries with poor economic and sanitary conditions. The clinical manifestations of Strongy...
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CD146 deficiency promotes inflammatory type 2 responses in pulmonary cryptococcosis
Cryptococcus neoformans ( C. neoformans ) is an important opportunistic fungal pathogen for pulmonary cryptococcosis. Previously, we demonstrated that...
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Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2
Severe viral pneumonia caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by a hyperinflammatory state...
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Brief report: community-acquired Friedlander’s pneumonia and pulmonary metastatic Klebsiella pneumoniae infection caused by hypervirulent ST23 in the Netherlands
Infections with hypervirulent Klebsiella pneumoniae (hvKp) commonly presents with primary liver infection, bacteremia, and metastatic abscesses....
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Pulmonary Side Effects of Immunotherapy
The effectiveness of drugs known as immune checkpoint inhibitors in the treatment of cancer is increasingly well understood. The use of immunotherapy...
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Cytomegalovirus pneumonia with intermittent pulmonary hemorrhage leading to asphyxia death: a case report and literature review
Neonatal pulmonary hemorrhage is a late manifestation of various diseases. Premature delivery and low body weight are frequently observed as...
