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The prevention strategies of swine viruses related to xenotransplantation
Xenotransplantation is considered a solution for the shortage of organs, and pigs play an indispensable role as donors in xenotransplantation. The...
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Animal Models for Hepatitis E Virus
Animal models are one of the most important tools in the study of human hepatitis E virus (HEV) infection. They are particularly important in light... -
Pigs (Sus Scrofa) in Biomedical Research
Much of biomedical oriented research is conducted with animal models. Over the years, rodents (primarily rats and mice) have emerged as the preferred... -
Phylogeny and Genetic Diversity of Philippine Native Pigs (Sus scrofa) as Revealed by Mitochondrial DNA Analysis
Philippine native pigs (PhNP) are small black pigs domesticated in rural communities in the Philippines. They are valued locally for their various...
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Presence of porcine cytomegalovirus, a porcine roseolovirus, in wild boars in Italy and Germany
Porcine cytomegalovirus (PCMV), a porcine roseolovirus (PRV) that is closely related to human herpesviruses 6 and 7, is commonly found in commercial...
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Wireless closed-loop deep brain stimulation using microelectrode array probes
Deep brain stimulation (DBS), including optical stimulation and electrical stimulation, has been demonstrated considerable value in exploring...
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Recent advances in the use of the CRISPR-Cas system for the detection of infectious pathogens
Infectious diseases cause great economic loss and individual and even social anguish. Existing detection methods lack sensitivity and specificity,...
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Development of Molecular Markers Based on the L1 Retrotransposon Insertion Polymorphisms in Pigs (Sus scrofa) and Their Association with Economic Traits
AbstractMolecular markers based on retrotransposon insertion polymorphisms (RTIPs) have great potential in studies of animal genetics and breeding....
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Screening pigs for xenotransplantation in China: investigation of porcine endogenous retrovirus in Diannan small-eared pigs
Porcine endogenous retrovirus (PERV), which integrates as a provirus into the genome of pig cells, is an important biosafety issue in...
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Porcine models for studying complications and organ crosstalk in diabetes mellitus
The worldwide prevalence of diabetes mellitus and obesity is rapidly increasing not only in adults but also in children and adolescents. Diabetes is...
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See Teresa of Ávila. -
Delivery of human erythropoietin gene with an adeno-associated virus vector through parotid glands to treat renal anaemia in a swine model
Anaemia is a common complication of chronic kidney disease, for which there is presently no adequate treatment. The delivery of human erythropoietin...
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Hypothalamus
A major function of the nervous system is to maintain the constancy of the internal environment. In 1878, Claude Bernard pointed out the remarkable... -
Nanotechnology-based antiviral therapeutics
The host immune system is highly compromised in case of viral infections and relapses are very common. The capacity of the virus to destroy the host...
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Interleukin-7 and Immunorejuvenation
Estimates of the global population in 2016 suggest it to be approximately 7334 million of which more than 930 million are over 60 years of age. This... -
Interleukin-7 and Immunorejuvenation
Estimates of the global population in 2016 suggest it to be approximately 7334 million of which more than 930 million are over 60 years of age. This... -
Eukaryotic Genome Organization, Regulation, Evolution and Control
This chapter aims to show the vital components of eukaryotic genomes such as chromosome structure, genome duplications, transposons, satellite DNA.... -
History of Development of Gastrointestinal Physiology: From Antiquity to Modern Period and the Birth of Modern Digestive Physiology
Curiosity and the quest for addressing human maladies or problems of nature are possibly the key driving forces for discoveries in science. Apart... -
Miniature pigs of ICG as a model object for morphogenetic research
This paper provides a relatively complete description of the genesis, formation conditions, and the genealogic and genetic structure of the ICG...