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Assembly of Large Icosahedral Double-Stranded RNA Viruses
Double-stranded RNA (dsRNA) viruses are a diverse group of viruses infecting hosts from bacteria to higher eukaryotes. Among the hosts are humans,...
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The genomic constellation of a novel avian orthoreovirus strain associated with runting-stunting syndrome in broilers
Avian orthoreoviruses (ARVs) are responsible for considerable economic losses in broiler chickens; yet, the genetic characterization of most ARV...
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Introduction: Nipah Virus—Discovery and Origin
Until the Nipah outbreak in Malaysia in 1999, knowledge of human infections with the henipaviruses was limited to the small number of cases...
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Functional investigation of grass carp reovirus nonstructural protein NS80
BackgroundGrass Carp Reovirus (GCRV), a highly virulent agent of aquatic animals, has an eleven segmented dsRNA genome encased in a multilayered...
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Suppression of RNA interference pathway in vitro by Grass carp reovirus
The means of survival of genomic dsRNA of reoviruses from dsRNA-triggered and Dicer-initiated RNAi pathway remains to be defined. The present study...
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Avian reovirus triggers autophagy in primary chicken fibroblast cells and Vero cells to promote virus production
Avian reovirus (ARV) is an important cause of disease in poultry. Although ARV is known to induce apoptosis in infected cells, the interaction...
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A potentially novel reovirus isolated from swine in northeastern China in 2007
We report a novel reovirus (MRV-HLJ/2007) isolated from swine in Heilongjiang Province, China. Genome sequence analysis indicated a close genetic...
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A novel sapelovirus-like virus isolation from wild boar
A novel sapelovirus-like virus was isolated from a wild boar ( Sus scrofa ). In this study, partial viral genomic nucleotide sequences were determined...
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The use of an in vitro microneutralization assay to evaluate the potential of recombinant VP5 protein as an antigen for vaccinating against Grass carp reovirus
BackgroundGrass carp reovirus (GCRV) is the causative pathogen of grass carp hemorrhagic disease, one of the major diseases damaging grass carp Ctenop...
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** River virus, a new bat reovirus isolated in southern China
Nelson Bay orthoreovirus (NBV) is a species in the genus Orthoreovirus , family Reoviridae , containing 4, possibly 5, members. Here, we report a...
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Avian reovirus S1133-induced DNA damage signaling and subsequent apoptosis in cultured cells and in chickens
In this study, intracellular signaling in ARV S1133-mediated apoptosis was investigated. A microarray was used to examine the gene expression...
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A novel totivirus and piscine reovirus (PRV) in Atlantic salmon (Salmo salar) with cardiomyopathy syndrome (CMS)
BackgroundCardiomyopathy syndrome (CMS) is a severe disease affecting large farmed Atlantic salmon. Mortality often appears without prior clinical...
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Characterization of the nonstructural protein NS80 of grass carp reovirus
Nonstructural proteins of members of the family Reoviridae are believed to play significant roles in the virus replication cycle. Phylogenetic...
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Expression of rice gall dwarf virus outer coat protein gene (S8) in insect cells
To obtain the P8 protein of Rice gall dwarf virus (RGDV) with biological activity, its outer coat protein gene S8 was expressed in Spodoptera...
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Rice black-streaked dwarf virus P6 self-interacts to form punctate, viroplasm-like structures in the cytoplasm and recruits viroplasm-associated protein P9-1
BackgroundRice black-streaked dwarf virus (RBSDV), a member of the genus Fijivirus within the family Reoviridae , can infect several graminaceous...
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Molecular analysis of grass carp reovirus HZ08 genome segments 1–3 and 5–6
A new grass carp reovirus, assigned HZ08, was isolated from a diseased grass carp case during routine examination in Huzhou City, Zhejiang Province,...
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ADARs: Viruses and Innate Immunity
Double-stranded RNA (dsRNA) functions both as a substrate of ADARs and also as a molecular trigger of innate immune responses. ADARs, adenosine...
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Rotavirus Cell Entry
Infecting nearly every child by age five, rotaviruses are the major causative agents of severe gastroenteritis in young children. While much is known...
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Reiseimpfungen und allgemein empfohlene Impfungen
Nach Schätzungen der World Tourism Organisation (WTO) verreisen jedes Jahr ca. 7,2 Millionen Deutsche nach Übersee. Hiervon entfällt ein Großteil auf...