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A Global Perspective of Cancer Prevalence: The Causative Agent, the Environment, or the Genes?
Cancer is among the most leading causes of death worldwide, while breast and prostate cancers are the leading causes of cancers among females and...
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Oral Cancer and Oxidative Stress
Oral squamous cell carcinoma (OSCC) is one of the common forms of oral cancer associated with significant morbidity and mortality. Over several...
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Diagnostic accuracy of intraoperative frozen section for margin evaluation of oral cavity squamous cell carcinoma
ObjectivesIntraoperative frozen-section evaluation is a valuable technique for detecting positive margins intraoperatively for oral squamous cell...
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Rituximab in combination with gemcitabine plus cisplatin in patients with recurrent and metastatic head and neck squamous cell carcinoma: a phase I trial
BackgroundThe treatment of recurrent or metastatic head and neck squamous-cell carcinoma (R/M HNSCC) remains challenging. Preclinical studies...
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Nrf2/HO-1 Alleviates Disulfiram/Copper-Induced Ferroptosis in Oral Squamous Cell Carcinoma
Accumulating evidence indicates that the disulfiram/copper complex (DSF/Cu) has been shown to have potent antitumor activity against various cancers....
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Association between smokeless tobacco use and oral cavity cancer risk in women compared with men: a systematic review and meta-analysis
BackgroundThe impact of smokeless tobacco (SLT) use on the risk of oral cavity cancer (OCC) has been confirmed; however, the sex-based difference in...
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Cancer Genomics and Diagnostics: Northeast Indian Scenario
Cancer genomics, which deals with the study of the sum of DNA sequence and differences in patterns of gene expression between cancerous cells and...
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Human Family 1–4 cytochrome P450 enzymes involved in the metabolic activation of xenobiotic and physiological chemicals: an update
This is an overview of the metabolic activation of drugs, natural products, physiological compounds, and general chemicals by the catalytic activity...
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Comparative proteomics of oral squamous cell carcinoma tissue in consumers and non-consumers of tobacco
BackgroundTobacco is a risk factor for oral squamous cell carcinoma (OSCC). Some cases of OSCC occur without any known cause and is called idiopathic...
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Risk Factors for Oral Squamous Cell Carcinoma in the Indian Population
Oral cancer is caused by a combination of multiple extrinsic and intrinsic risk factors acting over a long period of time. Tobacco is the primary...
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Polyphenol-based targeted therapy for oral submucous fibrosis
Oral submucous fibrosis (OSF) is a chronic, progressive, and precancerous condition mainly caused by chewing areca nut. Currently, OSF therapy...
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Securin overexpression correlates with the activated Rb/E2F1 pathway and histone H3 epigenetic modifications in raw areca nut-induced carcinogenesis in mice
BackgroundRaw areca nut (RAN) consumption induces oral, esophageal and gastric cancers, which are significantly associated with the overexpression of...
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Cholinergic Receptors and Addiction
Human behavior can be controlled by physical or psychological dependencies associated with addiction. One of the most insidious addictions in our...
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Recurrence of oral squamous cell carcinoma in surgically treated patients at Khartoum Teaching Dental Hospital retrospective cross-sectional study
BackgroundIn terms of survival rate, recurrent oral squamous cell carcinoma (OSCC) after primary surgery is considered as a poor prognostic indicator.
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Betel Quid Use and Oral Cancer in a High-Risk Refugee Community in the USA: The Effectiveness of an Awareness Initiative
Betel nut (BN) is a psychoactive oral carcinogen that is commonly used among Asian communities. This study aims to investigate BN usage patterns and...
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Reactive Oxygen Species in Oral Squamous Cell Carcinoma Progression and Importance of Stem Cells in Cancer Therapeutics
Oral squamous cell carcinoma is the most frequent oral malignancy worldwide classified under the head and neck cancer category. Reactive oxygen...
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Reactive Oxygen Species in Oral Squamous Cell Carcinoma Progression and Importance of Stem Cells in Cancer Therapeutics
Oral squamous cell carcinoma is the most frequent oral malignancy worldwide classified under the head and neck cancer category. Reactive oxygen...
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Effects of educational interventions based on the theory of planned behavior on oral cancer-related knowledge and tobacco smoking in adults: a cluster randomized controlled trial
BackgroundThe theory of planned behavior (TPB) is an effective model for facilitating behavioral change. The aim of the present study was to evaluate...
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Missed radiation therapy sessions in first three weeks predict distant metastasis and less favorable outcomes in surgically treated patients with oral cavity squamous cell carcinoma
BackgroundWe sought to investigate the prognostic impact of missed RT sessions in patients who had undergone surgery for oral cavity squamous cell...
