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Article
The role of caspase-8 in amyloid-induced beta cell death in human and mouse islets
Reduced beta cell mass due to increased beta cell apoptosis is a key defect in type 2 diabetes. Islet amyloid, formed by the aggregation of human islet amyloid polypeptide (hIAPP), contributes to beta cell dea...
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Article
Establishing a cGMP pancreatic islet processing facility: the first experience in Iran
It has been predicted that one of the greatest increase in prevalence of diabetes will happen in the Middle East bear in the next decades. The aim of standard therapeutic strategies for diabetes is better cont...
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Article
An Odyssey of Islet Transplantation for Therapy of Type 1 Diabetes
Canadian surgical contributions to the field of islet transplantation have a rich heritage and a promising future. In this article, some seminal Canadian contributions to this field are reviewed, including con...
