4 Result(s)

Article

ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells

Numerous signaling pathways have been demonstrated experimentally to affect the pathogenesis of cerebral cavernous malformations (CCM), a disease that can be caused by CCM3 deficiency. However, the understandi...

Kang Wang, Haixuan Chen, Zhongyang Zhou, Haifeng Zhang… in Cell & Bioscience (2021)

Article

METTL1-mediated m⁷G methylation maintains pluripotency in human stem cells and limits mesoderm differentiation and vascular development

7-Methylguanosine (m⁷G) is one of the most conserved modifications in nucleosides within tRNAs and rRNAs. It plays essential roles in the regulation of mRNA export, splicing, and translation. Recent studies highl...

Yujie Deng, Zhongyang Zhou, Weidong Ji, Shuibin Lin… in Stem Cell Research & Therapy (2020)

Article

Dynamic m⁶A mRNA methylation reveals the role of METTL3-m⁶A-CDCP1 signaling axis in chemical carcinogenesis

N6-methyladenosine (m⁶A) is the most abundant internal modification in mammalian mRNAs. Despite its functional importance in various physiological events, the role of m⁶A in chemical carcinogenesis remains largel...

Fan Yang, Huan **, Biao Que, Yinghui Chao, Haiqing Zhang, **aoling Ying… in Oncogene (2019)

Article

Next generation sequence analysis of the transcriptional response to neonatal hyperoxia

Soumyaroop Bhattacharya, Zhongyang Zhou, Min Yee, Ashley Lopez… in Molecular Cytogenetics (2014)