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Article
Open AccessRetinal inflammation in murine models of type 1 and type 2 diabetes with diabetic retinopathy
The loss of pericytes surrounding the retinal vasculature in early diabetic retinopathy underlies changes to the neurovascular unit that lead to more destructive forms of the disease. However, it is unclear wh...
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Article
Chrysin ameliorates diabetes-associated cognitive deficits in Wistar rats
Chrysin (CH) is an important natural plant flavonoid and possesses diverse pharmacological activities. Our present investigations aimed to assess the neuroprotection of CH against diabetes-associated cognitive...
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Protocol
Measurement of Glomerular Filtration Rate in Conscious Mice
Glomerular filtration rate (GFR) is an important index of renal function and routinely used in patient care and basic research to evaluate progression of renal diseases or test the efficacy of novel therapeuti...
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Article
Examining diabetic nephropathy through the lens of mouse genetics
Although diabetic nephropathy occurs in only a minority of patients with diabetes, it is the major cause of end-stage renal disease in the United States. Hyperglycemia and hypertension are important factors pr...